Experiment set10S181 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 5mM Inosine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS00375 +5.2 26.6 ammonium transporter compare
MMP_RS08320 +5.0 8.5 molybdopterin molybdotransferase MoeA compare
MMP_RS04885 +4.4 27.3 sulfite exporter TauE/SafE family protein compare
MMP_RS02885 +4.2 13.6 molybdopterin biosynthesis protein compare
MMP_RS02225 +3.6 16.4 carbohydrate kinase family protein compare
MMP_RS08310 +2.7 3.9 TMEM165/GDT1 family protein compare
MMP_RS06325 +2.4 2.7 hypothetical protein compare
MMP_RS03340 +2.2 1.7 ABC transporter ATP-binding protein compare
MMP_RS08275 +2.0 8.6 hypothetical protein compare
MMP_RS01435 +2.0 5.1 DMT family transporter compare
MMP_RS05355 +1.9 1.2 hypothetical protein compare
MMP_RS00325 +1.9 2.1 RNA-binding protein compare
MMP_RS00130 +1.9 1.7 nickel-responsive transcriptional regulator NikR compare
MMP_RS08160 +1.8 4.7 EamA family transporter compare
MMP_RS08940 +1.8 1.7 MetS family NSS transporter small subunit compare
MMP_RS08725 +1.8 1.2 Ni/Fe hydrogenase subunit alpha compare
MMP_RS01430 +1.7 6.5 mechanosensitive ion channel family protein compare
MMP_RS09055 +1.6 1.1 CAP domain-containing protein compare
MMP_RS06345 +1.6 7.9 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS07765 +1.6 6.3 sodium:alanine symporter family protein compare
MMP_RS05975 +1.6 1.7 hypothetical protein compare
MMP_RS08750 +1.5 4.3 hypothetical protein compare
MMP_RS02495 +1.5 2.7 hypothetical protein compare
MMP_RS08760 +1.4 2.3 hypothetical protein compare
MMP_RS08555 +1.4 2.8 hypothetical protein compare
MMP_RS08280 +1.3 2.9 proteasome assembly chaperone family protein compare
MMP_RS03320 +1.3 2.0 metal-dependent transcriptional regulator compare
MMP_RS03065 +1.3 1.8 AzlC family ABC transporter permease compare
MMP_RS06720 +1.3 3.4 response regulator transcription factor compare
MMP_RS07835 +1.3 4.0 TldD/PmbA family protein compare
MMP_RS06685 +1.3 4.9 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08930 +1.3 1.5 hypothetical protein compare
MMP_RS07915 +1.3 3.3 DUF4870 domain-containing protein compare
MMP_RS07800 +1.2 3.6 ATP-binding cassette domain-containing protein compare
MMP_RS00430 +1.2 1.7 hypothetical protein compare
MMP_RS09050 +1.2 2.2 CAP domain-containing protein compare
MMP_RS06365 +1.2 2.0 hypothetical protein compare
MMP_RS08485 +1.1 2.8 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS08665 +1.1 5.1 hypothetical protein compare
MMP_RS00385 +1.1 3.0 P-II family nitrogen regulator compare
MMP_RS00390 +1.1 4.4 ammonium transporter compare
MMP_RS00940 +1.1 3.5 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS06585 +1.1 1.3 DMT family protein compare
MMP_RS06515 +1.0 0.8 UPF0489 family protein compare
MMP_RS00710 +1.0 1.9 hypothetical protein compare
MMP_RS05175 +1.0 1.7 hypothetical protein compare
MMP_RS03550 +1.0 1.6 DUF2124 domain-containing protein compare
MMP_RS01135 +1.0 3.4 molybdate ABC transporter substrate-binding protein conserved
MMP_RS03910 +1.0 1.7 hypothetical protein compare
MMP_RS04125 +1.0 1.7 TetR/AcrR family transcriptional regulator compare
MMP_RS08400 +1.0 2.2 MJ0307 family thioredoxin compare
MMP_RS02835 +1.0 1.4 CGGC domain-containing protein compare
MMP_RS09025 +1.0 0.7 hypothetical protein compare
MMP_RS07560 +1.0 1.8 prefoldin subunit alpha compare
MMP_RS08075 +0.9 3.6 DUF749 domain-containing protein compare
MMP_RS08415 +0.9 1.5 radical SAM protein compare
MMP_RS07155 +0.9 3.1 MFS transporter compare
MMP_RS06905 +0.9 1.5 hypothetical protein compare
MMP_RS01200 +0.9 1.6 hypothetical protein compare
MMP_RS01495 +0.9 2.9 TraB/GumN family protein compare
MMP_RS08590 +0.9 1.4 flagellin compare
MMP_RS08830 +0.9 1.4 GTP-binding protein compare
MMP_RS05830 +0.9 1.7 peptidyl-prolyl cis-trans isomerase compare
MMP_RS04225 +0.9 1.9 hypothetical protein compare
MMP_RS02985 +0.9 2.1 hypothetical protein compare
MMP_RS05470 +0.9 3.1 DUF523 and DUF1722 domain-containing protein compare
MMP_RS01785 +0.8 1.9 hypothetical protein compare
MMP_RS01550 +0.8 3.5 DUF1624 domain-containing protein compare
MMP_RS02815 +0.8 1.7 hypothetical protein compare
MMP_RS05090 +0.8 2.2 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS05665 +0.8 2.1 phosphate ABC transporter permease subunit PstC compare
MMP_RS03250 +0.8 1.0 MJ1244 family protein compare
MMP_RS08615 +0.8 1.2 flagellar protein G compare
MMP_RS08770 +0.8 4.1 hypothetical protein compare
MMP_RS07890 +0.8 1.1 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS03215 +0.8 3.6 MBL fold metallo-hydrolase compare
MMP_RS01660 +0.8 1.7 hypothetical protein compare
MMP_RS05985 +0.8 1.3 hypothetical protein compare
MMP_RS00830 +0.8 1.3 purine phosphoribosyltransferase family protein compare
MMP_RS00760 +0.8 3.0 branched-chain-amino-acid transaminase compare
MMP_RS03425 +0.8 2.7 hypothetical protein compare
MMP_RS01650 +0.8 0.6 sulfurtransferase TusA family protein compare
MMP_RS08285 +0.8 2.6 serine/threonine protein kinase compare
MMP_RS01195 +0.8 0.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06150 +0.8 3.2 hypothetical protein compare
MMP_RS01055 +0.8 1.6 hypothetical protein compare
MMP_RS02405 +0.8 1.7 hypothetical protein compare
MMP_RS08235 +0.7 2.3 hypothetical protein compare
MMP_RS02790 +0.7 0.6 class III signal peptide-containing protein compare
MMP_RS00930 +0.7 2.4 ABC transporter permease compare
MMP_RS06965 +0.7 1.6 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS03880 +0.7 4.5 Fic family protein compare
MMP_RS08430 +0.7 2.1 HAD family hydrolase compare
MMP_RS04305 +0.7 1.3 hypothetical protein compare
MMP_RS04410 +0.7 1.8 hypothetical protein compare
MMP_RS08380 +0.7 1.7 phosphatase PAP2 family protein compare
MMP_RS05785 +0.7 3.9 ATP-binding protein compare
MMP_RS06440 +0.7 2.3 CBS domain-containing protein compare
MMP_RS06840 +0.7 0.4 DNA-directed RNA polymerase subunit N compare
MMP_RS06500 +0.7 2.5 ATP-binding protein compare
MMP_RS01960 +0.7 0.5 hypothetical protein compare
MMP_RS08675 +0.7 0.8 class III signal peptide-containing protein compare
MMP_RS00475 +0.7 2.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS00250 +0.7 3.6 Flp pilus assembly complex ATPase component TadA compare
MMP_RS08700 +0.7 1.8 hypothetical protein compare
MMP_RS08640 +0.7 3.0 TIM barrel protein compare
MMP_RS00245 +0.7 4.2 type II secretion system F family protein compare
MMP_RS02540 +0.7 1.8 DUF2283 domain-containing protein compare
MMP_RS02395 +0.7 2.0 hypothetical protein compare
MMP_RS08775 +0.7 1.2 methanogenesis marker 9 domain-containing protein compare
MMP_RS07895 +0.7 0.7 cytochrome c compare
MMP_RS03780 +0.7 1.4 4Fe-4S binding protein compare
MMP_RS07715 +0.7 2.7 YfcE family phosphodiesterase compare
MMP_RS02545 +0.6 1.2 hypothetical protein compare
MMP_RS03465 +0.6 0.6 adenine phosphoribosyltransferase compare
MMP_RS01280 +0.6 3.2 DUF515 domain-containing protein compare
MMP_RS05720 +0.6 1.8 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS06075 +0.6 2.0 class I SAM-dependent methyltransferase compare
MMP_RS01160 +0.6 1.8 DMT family transporter compare
MMP_RS05790 +0.6 2.2 HDIG domain-containing protein compare
MMP_RS00240 +0.6 3.4 type II secretion system F family protein compare
MMP_RS07625 +0.6 1.2 cobalt ECF transporter T component CbiQ compare
MMP_RS02390 +0.6 0.8 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS05035 +0.6 2.6 hypothetical protein compare
MMP_RS04310 +0.6 1.2 hypothetical protein compare
MMP_RS06590 +0.6 1.0 GNAT family N-acetyltransferase compare
MMP_RS01415 +0.6 0.9 DUF2067 domain-containing protein compare
MMP_RS01940 +0.6 1.4 MoxR family ATPase compare
MMP_RS05070 +0.6 1.7 4Fe-4S dicluster domain-containing protein compare
MMP_RS06545 +0.6 1.4 ferredoxin family protein compare
MMP_RS01290 +0.6 2.7 class III signal peptide-containing protein compare
MMP_RS05490 +0.6 1.9 IMPACT family protein compare
MMP_RS02605 +0.6 0.3 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS09065 +0.6 2.8 hypothetical protein compare
MMP_RS01965 +0.6 0.8 DUF1616 domain-containing protein compare
MMP_RS04630 +0.6 1.8 3'-5' exonuclease compare
MMP_RS07910 +0.6 2.0 NAD(P)H-hydrate dehydratase compare
MMP_RS02475 +0.6 1.1 hypothetical protein compare
MMP_RS00435 +0.6 2.9 CPBP family intramembrane metalloprotease compare
MMP_RS04985 +0.6 1.4 DUF2180 family protein compare
MMP_RS09030 +0.6 1.7 hypothetical protein compare
MMP_RS07550 +0.6 2.4 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha compare
MMP_RS07420 +0.6 1.9 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06525 +0.6 0.5 YciI family protein compare
MMP_RS03405 +0.6 1.6 RNA 3'-terminal phosphate cyclase compare
MMP_RS00910 +0.6 1.9 2-phosphosulfolactate phosphatase compare
MMP_RS00290 +0.6 1.3 hypothetical protein compare
MMP_RS00185 +0.6 2.7 potassium channel protein compare
MMP_RS05965 +0.6 1.0 carboxymuconolactone decarboxylase family protein compare
MMP_RS03100 +0.6 0.9 hypothetical protein compare
MMP_RS01475 +0.6 1.4 phosphosulfolactate synthase compare
MMP_RS01680 +0.6 2.5 phenylacetate--CoA ligase compare
MMP_RS02500 +0.6 1.0 minichromosome maintenance protein MCM compare
MMP_RS06485 +0.6 0.3 zinc ribbon domain-containing protein compare
MMP_RS00955 +0.6 2.3 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS08890 +0.6 3.0 glycosyltransferase family 4 protein compare
MMP_RS06320 +0.6 1.8 hypothetical protein compare
MMP_RS02365 +0.5 1.4 nitrogen fixation compare
MMP_RS06715 +0.5 2.3 cache domain-containing protein compare
MMP_RS01090 +0.5 2.2 ABC transporter substrate-binding protein compare
MMP_RS08995 +0.5 0.5 hypothetical protein compare
MMP_RS03130 +0.5 1.6 hypothetical protein compare
MMP_RS01655 +0.5 1.2 DsrE family protein compare
MMP_RS04105 +0.5 1.6 MarR family transcriptional regulator compare
MMP_RS06975 +0.5 0.7 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS05770 +0.5 1.5 YkgJ family cysteine cluster protein compare
MMP_RS06530 +0.5 1.0 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS01145 +0.5 1.5 ABC transporter ATP-binding protein compare
MMP_RS08455 +0.5 1.3 multiprotein bridging factor aMBF1 compare
MMP_RS08385 +0.5 1.4 ABC transporter substrate-binding protein compare
MMP_RS01165 +0.5 0.9 DUF434 domain-containing protein compare
MMP_RS04495 +0.5 1.4 cation:proton antiporter compare
MMP_RS07840 +0.5 0.5 ribonuclease III compare
MMP_RS07615 +0.5 1.1 energy-coupling factor ABC transporter permease compare
MMP_RS07590 +0.5 2.0 hypothetical protein compare
MMP_RS08670 +0.5 1.5 metallophosphoesterase compare
MMP_RS02020 +0.5 1.0 gamma-glutamylcyclotransferase compare
MMP_RS01855 +0.5 1.3 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS02695 +0.5 1.5 formylmethanofuran dehydrogenase subunit A compare
MMP_RS05960 +0.5 2.1 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS05235 +0.5 1.5 exodeoxyribonuclease III compare
MMP_RS07805 +0.5 2.0 ABC transporter permease compare
MMP_RS00125 +0.5 0.4 DUF2798 domain-containing protein compare
MMP_RS03980 +0.5 2.1 hypothetical protein compare
MMP_RS02300 +0.5 0.9 NAD(P)H-dependent oxidoreductase compare
MMP_RS06065 +0.5 2.4 iron ABC transporter substrate-binding protein compare
MMP_RS02590 +0.5 1.6 low molecular weight phosphatase family protein compare
MMP_RS06660 +0.5 2.0 glycosyltransferase family 4 protein compare
MMP_RS01295 +0.5 1.7 hypothetical protein compare
MMP_RS02635 +0.5 1.5 class I SAM-dependent methyltransferase compare
MMP_RS02530 +0.5 2.1 type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family compare
MMP_RS00965 +0.5 0.5 hypothetical protein compare
MMP_RS07100 +0.5 1.8 hypothetical protein compare
MMP_RS02325 +0.5 1.2 epoxyqueuosine reductase compare
MMP_RS06650 +0.4 1.9 glycoside hydrolase family 57 protein compare
MMP_RS04270 +0.4 1.3 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06560 +0.4 1.6 hypothetical protein compare
MMP_RS03735 +0.4 1.6 indolepyruvate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01285 +0.4 1.6 hypothetical protein compare
MMP_RS03900 +0.4 1.4 minichromosome maintenance protein MCM compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source Inosine in Methanococcus maripaludis S2

For nitrogen source Inosine across organisms