Experiment set10S180 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM Thymidine

200 most important genes:

  gene name fitness t score description  
MMP_RS06400 -6.7 -2.1 4Fe-4S binding protein compare
MMP_RS01020 -6.5 -1.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS03960 -5.8 -1.8 hypothetical protein compare
MMP_RS01005 -5.0 -1.3 riboflavin synthase compare
MMP_RS03435 -5.0 -2.7 ketol-acid reductoisomerase compare
MMP_RS02675 -4.9 -4.7 hypothetical protein compare
MMP_RS07345 -4.8 -9.7 glycine synthesis protein GlyXL (from data) compare
MMP_RS04710 -4.8 -2.7 hypothetical protein compare
MMP_RS02145 -4.8 -15.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS04465 -4.8 -25.3 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS02010 -4.8 -11.2 PHP domain-containing protein compare
MMP_RS01755 -4.7 -1.2 DUF2097 domain-containing protein compare
MMP_RS04450 -4.7 -19.2 P-II family nitrogen regulator compare
MMP_RS06475 -4.6 -7.6 FAD-dependent oxidoreductase compare
MMP_RS04460 -4.6 -23.6 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS01830 -4.6 -2.3 tRNA-Val compare
MMP_RS04445 -4.6 -10.5 P-II family nitrogen regulator compare
MMP_RS04455 -4.5 -22.2 nitrogenase subunit alpha compare
MMP_RS05345 -4.5 -10.3 hypothetical protein compare
MMP_RS04470 -4.4 -19.6 nitrogenase compare
MMP_RS02355 -4.4 -4.9 30S ribosomal protein S27ae compare
MMP_RS08165 -4.4 -4.0 phosphoglycerate dehydrogenase compare
MMP_RS02670 -4.4 -14.6 ATP-binding cassette domain-containing protein compare
MMP_RS04890 -4.4 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS04440 -4.3 -14.4 nitrogenase iron protein compare
MMP_RS05500 -4.3 -13.8 2-isopropylmalate synthase compare
MMP_RS06285 -4.3 -3.3 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03600 -4.2 -3.3 triose-phosphate isomerase compare
MMP_RS03450 -4.2 -3.2 glycine synthesis protein GlyXS (from data) compare
MMP_RS02680 -4.1 -8.0 ABC transporter permease compare
MMP_RS00555 -4.1 -12.3 MFS transporter compare
MMP_RS02685 -4.1 -10.5 molybdate ABC transporter substrate-binding protein compare
MMP_RS01545 -4.1 -1.5 CBS domain-containing protein compare
MMP_RS08720 -4.1 -2.4 4Fe-4S binding protein compare
MMP_RS07635 -4.1 -13.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS01455 -4.1 -10.5 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS07845 -4.0 -3.6 LL-diaminopimelate aminotransferase compare
MMP_RS01500 -4.0 -3.0 CBS domain-containing protein compare
MMP_RS05920 -4.0 -0.7 50S ribosomal protein L37e compare
MMP_RS00300 -4.0 -1.0 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS07380 -3.8 -3.2 transcription elongation factor Spt5 compare
MMP_RS06915 -3.8 -10.8 metallophosphoesterase compare
MMP_RS01725 -3.8 -7.2 class I SAM-dependent methyltransferase family protein compare
MMP_RS07185 -3.8 -17.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS09020 -3.8 -2.5 hypothetical protein compare
MMP_RS06920 -3.7 -16.7 AAA family ATPase compare
MMP_RS07730 -3.7 -2.7 pyruvate synthase subunit beta compare
MMP_RS01385 -3.7 -0.9 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03035 -3.7 -4.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS07525 -3.7 -9.6 4Fe-4S binding protein compare
MMP_RS08860 -3.7 -7.3 MinD/ParA family protein compare
MMP_RS07365 -3.7 -15.3 2-phosphoglycerate kinase compare
MMP_RS00455 -3.6 -10.5 orotate phosphoribosyltransferase-like protein compare
MMP_RS06725 -3.6 -16.4 hypothetical protein compare
MMP_RS02730 -3.6 -12.9 ModD protein compare
MMP_RS01175 -3.6 -4.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03700 -3.6 -11.1 sodium:proton antiporter compare
MMP_RS01380 -3.5 -8.7 PHP domain-containing protein compare
MMP_RS02245 -3.5 -4.0 hypothetical protein compare
MMP_RS03110 -3.5 -8.1 glycosyltransferase family 2 protein compare
MMP_RS00040 -3.4 -7.7 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS03025 -3.4 -9.0 molybdenum cofactor guanylyltransferase compare
MMP_RS08635 -3.4 -2.5 UbiA family prenyltransferase compare
MMP_RS08650 -3.4 -5.3 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS04215 -3.4 -11.2 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS08645 -3.4 -11.1 UPF0179 family protein compare
MMP_RS06375 -3.4 -7.4 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS07435 -3.3 -3.2 GMP synthase subunit A compare
MMP_RS04090 -3.3 -3.8 hypothetical protein compare
MMP_RS07445 -3.3 -7.3 helix-turn-helix domain-containing protein compare
MMP_RS07390 -3.3 -3.6 cell division protein FtsZ compare
MMP_RS02195 -3.3 -5.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07600 -3.2 -3.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS00915 -3.2 -10.2 DUF116 domain-containing protein compare
MMP_RS08660 -3.2 -10.5 DHH family phosphoesterase compare
MMP_RS08500 -3.2 -7.2 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS07005 -3.2 -0.8 4Fe-4S binding protein compare
MMP_RS04780 -3.1 -3.9 ribonuclease P compare
MMP_RS00515 -3.1 -1.1 DUF655 domain-containing protein compare
MMP_RS06730 -3.1 -2.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS01225 -3.1 -6.8 DUF5379 domain-containing protein compare
MMP_RS06270 -3.1 -6.9 TIGR00300 family protein compare
MMP_RS02340 -3.1 -2.8 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08435 -3.0 -3.3 Era-like GTP-binding protein compare
MMP_RS06670 -3.0 -7.5 glucose-6-phosphate isomerase compare
MMP_RS04585 -3.0 -12.3 AIR synthase related protein compare
MMP_RS06120 -3.0 -3.3 UPF0147 family protein compare
MMP_RS06975 -3.0 -2.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS00685 -3.0 -5.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07200 -3.0 -8.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00310 -3.0 -13.1 CBS domain-containing protein compare
MMP_RS00735 -2.9 -3.7 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS00725 -2.9 -9.0 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS04685 -2.9 -4.2 DUF126 domain-containing protein compare
MMP_RS08715 -2.8 -3.2 formylmethanofuran dehydrogenase subunit B compare
MMP_RS05430 -2.8 -6.6 TIGR00288 family NYN domain-containing protein compare
MMP_RS07605 -2.8 -4.4 diadenylate cyclase compare
MMP_RS05925 -2.8 -5.5 small nuclear ribonucleoprotein compare
MMP_RS07075 -2.8 -4.5 phosphomannomutase/phosphoglucomutase compare
MMP_RS05250 -2.7 -2.1 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01875 -2.7 -11.7 N-acetyltransferase compare
MMP_RS00730 -2.7 -10.4 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS04790 -2.7 -13.7 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS00985 -2.7 -7.2 CDC48 family AAA ATPase compare
MMP_RS01900 -2.7 -15.7 hypothetical protein compare
MMP_RS01925 -2.7 -11.2 DUF1616 domain-containing protein compare
MMP_RS06295 -2.7 -7.5 methanogenesis marker 14 protein compare
MMP_RS06625 -2.7 -2.2 DNA primase compare
MMP_RS08210 -2.7 -2.7 phosphatidylglycerophosphatase A compare
MMP_RS06230 -2.7 -3.3 helix-turn-helix domain-containing protein compare
MMP_RS02900 -2.6 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS02240 -2.6 -4.6 methanogenesis marker 7 protein compare
MMP_RS07695 -2.6 -9.3 DUF3236 domain-containing protein compare
MMP_RS01220 -2.6 -8.0 hypothetical protein compare
MMP_RS04850 -2.6 -19.0 UPF0254 family protein compare
MMP_RS00810 -2.6 -9.2 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07355 -2.6 -1.1 transcription factor S compare
MMP_RS06395 -2.5 -5.1 ThiF family adenylyltransferase compare
MMP_RS02345 -2.5 -4.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01265 -2.5 -2.3 hypothetical protein compare
MMP_RS03580 -2.5 -4.3 signal recognition particle-docking protein FtsY compare
MMP_RS03445 -2.5 -1.4 methanogenesis marker 17 protein compare
MMP_RS08195 -2.4 -10.8 hypothetical protein compare
MMP_RS03485 -2.4 -6.2 TIGR00267 family protein compare
MMP_RS00750 -2.4 -2.6 fumarate hydratase compare
MMP_RS06855 -2.4 -9.2 hypothetical protein compare
MMP_RS02280 -2.4 -1.2 DUF211 domain-containing protein compare
MMP_RS05265 -2.4 -2.4 2-isopropylmalate synthase compare
MMP_RS05515 -2.4 -9.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06895 -2.4 -2.4 selenocysteine-specific translation elongation factor compare
MMP_RS01885 -2.3 -11.1 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS05640 -2.3 -8.8 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS06885 -2.3 -3.7 50S ribosome-binding GTPase compare
MMP_RS07535 -2.3 -9.2 4Fe-4S binding protein compare
MMP_RS06355 -2.3 -1.8 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01610 -2.3 -4.6 hypothetical protein compare
MMP_RS01880 -2.3 -6.8 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01800 -2.3 -3.9 TIGR00303 family protein compare
MMP_RS08440 -2.3 -4.0 cell division protein SepF compare
MMP_RS05280 -2.2 -9.5 COG1361 S-layer family protein compare
MMP_RS06370 -2.2 -5.4 biotin synthase BioB compare
MMP_RS05765 -2.2 -6.4 M42 family metallopeptidase compare
MMP_RS05285 -2.2 -6.5 MMPL family transporter compare
MMP_RS03315 -2.2 -1.8 ferrous iron transport protein A compare
MMP_RS06020 -2.2 -4.8 archaeoflavoprotein AfpA compare
MMP_RS07710 -2.2 -6.9 cell division protein FtsZ compare
MMP_RS05020 -2.1 -4.8 hypothetical protein compare
MMP_RS01890 -2.1 -6.5 nucleotide sugar dehydrogenase compare
MMP_RS01795 -2.1 -1.6 methanogenesis marker 6 protein compare
MMP_RS07700 -2.1 -11.8 DUF1188 domain-containing protein compare
MMP_RS08155 -2.1 -8.8 hypothetical protein compare
MMP_RS01445 -2.1 -6.3 hypothetical protein compare
MMP_RS05540 -2.1 -3.1 hypothetical protein compare
MMP_RS00035 -2.1 -6.8 DUF2098 family protein compare
MMP_RS06315 -2.0 -1.0 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS05930 -2.0 -2.5 3-isopropylmalate dehydratase large subunit compare
MMP_RS07420 -2.0 -6.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS02225 -2.0 -8.0 carbohydrate kinase family protein compare
MMP_RS04870 -2.0 -5.5 TIGR02253 family HAD-type hydrolase compare
MMP_RS00720 -2.0 -8.1 metal-dependent hydrolase compare
MMP_RS01700 -2.0 -0.9 dihydroxy-acid dehydratase compare
MMP_RS04955 -2.0 -5.2 DNA topoisomerase I compare
MMP_RS01325 -2.0 -2.1 dihydroneopterin aldolase family protein compare
MMP_RS08300 -2.0 -1.2 metal-sulfur cluster assembly factor compare
MMP_RS03205 -2.0 -1.6 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS04500 -2.0 -13.1 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS00900 -1.9 -2.2 50S ribosomal protein L39e compare
MMP_RS03420 -1.9 -3.6 acetolactate synthase small subunit compare
MMP_RS07090 -1.9 -8.3 tRNA (adenine-N1)-methyltransferase compare
MMP_RS05535 -1.9 -2.7 hypothetical protein compare
MMP_RS08790 -1.9 -1.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS03015 -1.9 -7.6 GTP 3' 8-cyclase MoaA compare
MMP_RS02780 -1.9 -6.4 hypothetical protein compare
MMP_RS01895 -1.8 -11.5 flippase compare
MMP_RS07735 -1.8 -0.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS08570 -1.8 -8.9 coenzyme F420-0:L-glutamate ligase compare
MMP_RS04720 -1.8 -3.2 DedA family protein compare
MMP_RS03640 -1.8 -2.9 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01720 -1.8 -2.6 replication factor C large subunit compare
MMP_RS00315 -1.8 -6.9 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS07875 -1.7 -6.4 hypothetical protein compare
MMP_RS06175 -1.7 -4.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS07750 -1.7 -5.7 DUF357 domain-containing protein compare
MMP_RS00520 -1.7 -1.2 RNA polymerase Rpb4 family protein compare
MMP_RS05550 -1.7 -0.9 cation:proton antiporter compare
MMP_RS01915 -1.7 -9.2 DUF354 domain-containing protein compare
MMP_RS02190 -1.7 -3.1 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS06500 -1.7 -8.6 ATP-binding protein compare
MMP_RS07820 -1.7 -5.6 UPF0104 family protein compare
MMP_RS01665 -1.7 -2.1 DUF2111 domain-containing protein compare
MMP_RS03475 -1.6 -0.7 hypothetical protein compare
MMP_RS05425 -1.6 -4.7 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS08705 -1.6 -5.6 sulfopyruvate decarboxylase subunit beta compare
MMP_RS07180 -1.6 -5.2 DEAD/DEAH box helicase compare
MMP_RS02175 -1.6 -1.1 DUF1611 domain-containing protein compare
MMP_RS05460 -1.6 -9.9 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS00115 -1.6 -9.0 radical SAM protein compare
MMP_RS08460 -1.5 -2.9 proteasome-activating nucleotidase compare
MMP_RS02800 -1.5 -7.0 nucleotidyltransferase domain-containing protein compare
MMP_RS06340 -1.5 -5.7 phosphoadenosine phosphosulfate reductase family protein compare


Specific Phenotypes

For 9 genes in this experiment

For nitrogen source Thymidine in Methanococcus maripaludis S2

For nitrogen source Thymidine across organisms