Experiment set10S158 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Valine

200 most important genes:

  gene name fitness t score description  
MMP_RS01020 -5.2 -1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07845 -5.0 -2.6 LL-diaminopimelate aminotransferase compare
MMP_RS03450 -4.9 -2.9 glycine synthesis protein GlyXS (from data) compare
MMP_RS04450 -4.7 -15.7 P-II family nitrogen regulator compare
MMP_RS01175 -4.5 -4.9 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06475 -4.4 -6.1 FAD-dependent oxidoreductase compare
MMP_RS03435 -4.4 -2.5 ketol-acid reductoisomerase compare
MMP_RS04455 -4.4 -23.8 nitrogenase subunit alpha compare
MMP_RS04470 -4.4 -20.2 nitrogenase compare
MMP_RS03445 -4.4 -1.1 methanogenesis marker 17 protein compare
MMP_RS04460 -4.4 -24.4 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS02685 -4.3 -13.5 molybdate ABC transporter substrate-binding protein compare
MMP_RS02010 -4.3 -14.6 PHP domain-containing protein compare
MMP_RS04465 -4.2 -16.6 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS04440 -4.2 -13.0 nitrogenase iron protein compare
MMP_RS04445 -4.2 -9.6 P-II family nitrogen regulator compare
MMP_RS07525 -4.2 -9.2 4Fe-4S binding protein compare
MMP_RS07635 -4.1 -8.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07380 -4.1 -2.4 transcription elongation factor Spt5 compare
MMP_RS02680 -4.1 -8.6 ABC transporter permease compare
MMP_RS02670 -4.0 -12.8 ATP-binding cassette domain-containing protein compare
MMP_RS00555 -4.0 -10.3 MFS transporter compare
MMP_RS05920 -4.0 -0.6 50S ribosomal protein L37e compare
MMP_RS05500 -4.0 -10.6 2-isopropylmalate synthase compare
MMP_RS08165 -3.9 -3.4 phosphoglycerate dehydrogenase compare
MMP_RS01325 -3.9 -2.3 dihydroneopterin aldolase family protein compare
MMP_RS07345 -3.9 -8.1 glycine synthesis protein GlyXL (from data) compare
MMP_RS05925 -3.7 -5.0 small nuclear ribonucleoprotein compare
MMP_RS01225 -3.7 -6.4 DUF5379 domain-containing protein compare
MMP_RS07185 -3.6 -15.9 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02195 -3.6 -4.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS02730 -3.6 -11.2 ModD protein compare
MMP_RS01500 -3.5 -3.5 CBS domain-containing protein compare
MMP_RS03035 -3.5 -5.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04215 -3.5 -9.0 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS00685 -3.5 -4.3 2-phospho-L-lactate guanylyltransferase compare
MMP_RS00040 -3.5 -7.5 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS07605 -3.5 -5.0 diadenylate cyclase compare
MMP_RS00915 -3.4 -7.7 DUF116 domain-containing protein compare
MMP_RS04585 -3.4 -11.8 AIR synthase related protein compare
MMP_RS02675 -3.4 -3.4 hypothetical protein compare
MMP_RS06895 -3.3 -2.3 selenocysteine-specific translation elongation factor compare
MMP_RS08860 -3.3 -7.4 MinD/ParA family protein compare
MMP_RS06625 -3.3 -2.7 DNA primase compare
MMP_RS06400 -3.3 -1.6 4Fe-4S binding protein compare
MMP_RS02355 -3.3 -4.0 30S ribosomal protein S27ae compare
MMP_RS03025 -3.3 -7.5 molybdenum cofactor guanylyltransferase compare
MMP_RS01455 -3.3 -10.5 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS03700 -3.3 -10.6 sodium:proton antiporter compare
MMP_RS01005 -3.3 -1.5 riboflavin synthase compare
MMP_RS08500 -3.2 -6.6 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS08715 -3.2 -2.0 formylmethanofuran dehydrogenase subunit B compare
MMP_RS04710 -3.2 -2.4 hypothetical protein compare
MMP_RS08435 -3.2 -3.2 Era-like GTP-binding protein compare
MMP_RS06315 -3.2 -0.9 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS03600 -3.2 -2.2 triose-phosphate isomerase compare
MMP_RS01725 -3.2 -5.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS07445 -3.2 -7.2 helix-turn-helix domain-containing protein compare
MMP_RS01220 -3.1 -8.9 hypothetical protein compare
MMP_RS08300 -3.1 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS02900 -3.1 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS04090 -3.1 -3.2 hypothetical protein compare
MMP_RS06285 -3.1 -3.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07730 -3.1 -2.4 pyruvate synthase subunit beta compare
MMP_RS06295 -3.1 -8.1 methanogenesis marker 14 protein compare
MMP_RS01610 -3.1 -4.1 hypothetical protein compare
MMP_RS07365 -3.1 -15.6 2-phosphoglycerate kinase compare
MMP_RS06270 -3.1 -7.0 TIGR00300 family protein compare
MMP_RS07600 -3.1 -2.9 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS03110 -3.0 -9.2 glycosyltransferase family 2 protein compare
MMP_RS07355 -3.0 -1.0 transcription factor S compare
MMP_RS04685 -3.0 -3.7 DUF126 domain-containing protein compare
MMP_RS02245 -3.0 -4.1 hypothetical protein compare
MMP_RS06020 -3.0 -5.9 archaeoflavoprotein AfpA compare
MMP_RS06630 -3.0 -1.0 UPF0058 family protein compare
MMP_RS00310 -3.0 -9.7 CBS domain-containing protein compare
MMP_RS00810 -3.0 -7.7 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08645 -3.0 -10.4 UPF0179 family protein compare
MMP_RS03315 -2.9 -1.7 ferrous iron transport protein A compare
MMP_RS05930 -2.9 -2.7 3-isopropylmalate dehydratase large subunit compare
MMP_RS00455 -2.9 -9.3 orotate phosphoribosyltransferase-like protein compare
MMP_RS02800 -2.9 -8.1 nucleotidyltransferase domain-containing protein compare
MMP_RS06855 -2.8 -11.2 hypothetical protein compare
MMP_RS06925 -2.8 -3.4 ribonuclease VapC4 compare
MMP_RS02145 -2.8 -9.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS09020 -2.8 -2.0 hypothetical protein compare
MMP_RS05555 -2.8 -1.5 DUF4040 domain-containing protein compare
MMP_RS01755 -2.8 -1.3 DUF2097 domain-containing protein compare
MMP_RS03420 -2.8 -3.9 acetolactate synthase small subunit compare
MMP_RS06375 -2.8 -7.2 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS04870 -2.7 -6.5 TIGR02253 family HAD-type hydrolase compare
MMP_RS04900 -2.7 -16.9 hypothetical protein compare
MMP_RS00985 -2.7 -5.0 CDC48 family AAA ATPase compare
MMP_RS03640 -2.7 -3.9 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07955 -2.6 -6.0 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06885 -2.6 -2.6 50S ribosome-binding GTPase compare
MMP_RS05265 -2.6 -2.5 2-isopropylmalate synthase compare
MMP_RS07435 -2.6 -2.5 GMP synthase subunit A compare
MMP_RS08720 -2.6 -1.5 4Fe-4S binding protein compare
MMP_RS07390 -2.6 -3.6 cell division protein FtsZ compare
MMP_RS00750 -2.6 -2.5 fumarate hydratase compare
MMP_RS05430 -2.6 -7.4 TIGR00288 family NYN domain-containing protein compare
MMP_RS02175 -2.5 -1.0 DUF1611 domain-containing protein compare
MMP_RS00515 -2.5 -0.9 DUF655 domain-containing protein compare
MMP_RS01830 -2.5 -2.1 tRNA-Val compare
MMP_RS05550 -2.5 -0.8 cation:proton antiporter compare
MMP_RS06370 -2.5 -5.5 biotin synthase BioB compare
MMP_RS02240 -2.5 -3.4 methanogenesis marker 7 protein compare
MMP_RS06355 -2.5 -3.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS04890 -2.5 -1.0 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS04500 -2.5 -15.5 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06725 -2.4 -11.0 hypothetical protein compare
MMP_RS08210 -2.4 -2.7 phosphatidylglycerophosphatase A compare
MMP_RS07545 -2.4 -1.2 HTH domain-containing protein compare
MMP_RS06230 -2.4 -3.1 helix-turn-helix domain-containing protein compare
MMP_RS07200 -2.4 -7.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS08705 -2.4 -4.9 sulfopyruvate decarboxylase subunit beta compare
MMP_RS08790 -2.3 -2.0 translation initiation factor IF-2 subunit alpha compare
MMP_RS02345 -2.3 -3.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06975 -2.3 -2.4 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS08440 -2.3 -3.3 cell division protein SepF compare
MMP_RS01380 -2.3 -6.2 PHP domain-containing protein compare
MMP_RS05815 -2.3 -2.5 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07735 -2.3 -0.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS07005 -2.3 -0.6 4Fe-4S binding protein compare
MMP_RS07700 -2.2 -11.3 DUF1188 domain-containing protein compare
MMP_RS04790 -2.2 -9.6 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS01800 -2.2 -4.1 TIGR00303 family protein compare
MMP_RS00115 -2.2 -12.3 radical SAM protein compare
MMP_RS03440 -2.2 -1.4 MoaD/ThiS family protein compare
MMP_RS08650 -2.2 -3.6 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS08820 -2.2 -6.0 hypothetical protein compare
MMP_RS03580 -2.2 -3.7 signal recognition particle-docking protein FtsY compare
MMP_RS06120 -2.2 -2.4 UPF0147 family protein compare
MMP_RS00735 -2.2 -3.7 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06395 -2.1 -3.5 ThiF family adenylyltransferase compare
MMP_RS07710 -2.1 -6.7 cell division protein FtsZ compare
MMP_RS02190 -2.1 -3.6 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS08330 -2.1 -6.5 NADH-quinone oxidoreductase subunit H compare
MMP_RS08155 -2.1 -8.9 hypothetical protein compare
MMP_RS04955 -2.1 -6.8 DNA topoisomerase I compare
MMP_RS07535 -2.1 -9.5 4Fe-4S binding protein compare
MMP_RS00300 -2.1 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03090 -2.1 -6.1 cation:proton antiporter compare
MMP_RS07750 -2.1 -4.3 DUF357 domain-containing protein compare
MMP_RS05540 -2.0 -1.9 hypothetical protein compare
MMP_RS05345 -2.0 -7.7 hypothetical protein compare
MMP_RS08095 -2.0 -7.7 dethiobiotin synthase compare
MMP_RS08570 -2.0 -9.4 coenzyme F420-0:L-glutamate ligase compare
MMP_RS02340 -2.0 -1.7 DNA-directed RNA polymerase subunit E'' compare
MMP_RS00305 -2.0 -1.3 phosphoribosyl-ATP diphosphatase compare
MMP_RS07695 -1.9 -6.3 DUF3236 domain-containing protein compare
MMP_RS01385 -1.9 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01085 -1.9 -2.0 hypothetical protein compare
MMP_RS04850 -1.9 -12.4 UPF0254 family protein compare
MMP_RS05460 -1.9 -7.9 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS08660 -1.9 -7.0 DHH family phosphoesterase compare
MMP_RS01365 -1.9 -3.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01545 -1.9 -1.0 CBS domain-containing protein compare
MMP_RS02780 -1.9 -5.9 hypothetical protein compare
MMP_RS05535 -1.9 -4.4 hypothetical protein compare
MMP_RS01885 -1.9 -7.9 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS07075 -1.9 -3.3 phosphomannomutase/phosphoglucomutase compare
MMP_RS08195 -1.9 -7.4 hypothetical protein compare
MMP_RS01265 -1.8 -2.5 hypothetical protein compare
MMP_RS06105 -1.8 -8.4 hydrogenase maturation peptidase HycI compare
MMP_RS05640 -1.8 -6.4 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS05425 -1.8 -4.8 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06350 -1.8 -4.3 HesA/MoeB/ThiF family protein compare
MMP_RS01445 -1.8 -5.3 hypothetical protein compare
MMP_RS02135 -1.8 -3.9 DUF5612 domain-containing protein compare
MMP_RS00725 -1.8 -5.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS08855 -1.8 -8.4 hypothetical protein compare
MMP_RS06670 -1.8 -4.6 glucose-6-phosphate isomerase compare
MMP_RS07685 -1.8 -6.7 TIGR01212 family radical SAM protein compare
MMP_RS01875 -1.8 -7.4 N-acetyltransferase compare
MMP_RS05845 -1.8 -1.7 tRNA-intron lyase compare
MMP_RS06730 -1.8 -1.8 phosphopantothenate/pantothenate synthetase compare
MMP_RS01880 -1.7 -6.4 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS06175 -1.7 -5.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS03960 -1.7 -1.6 hypothetical protein compare
MMP_RS08460 -1.7 -2.3 proteasome-activating nucleotidase compare
MMP_RS05020 -1.7 -2.9 hypothetical protein compare
MMP_RS05250 -1.7 -1.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS07090 -1.7 -6.5 tRNA (adenine-N1)-methyltransferase compare
MMP_RS06900 -1.7 -3.2 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00730 -1.7 -3.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS08105 -1.7 -4.9 6-carboxyhexanoate--CoA ligase compare
MMP_RS00035 -1.7 -5.1 DUF2098 family protein compare
MMP_RS01700 -1.7 -0.8 dihydroxy-acid dehydratase compare
MMP_RS00695 -1.6 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS05295 -1.6 -7.6 minichromosome maintenance protein MCM compare
MMP_RS02875 -1.6 -6.3 chorismate pyruvate-lyase family protein compare
MMP_RS05440 -1.6 -6.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS00895 -1.6 -3.7 hypothetical protein compare
MMP_RS04875 -1.6 -4.0 energy-converting hydrogenase B subunit P compare
MMP_RS07860 -1.6 -0.9 hypothetical protein compare
MMP_RS01195 -1.6 -1.1 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS00320 -1.6 -1.5 class I SAM-dependent methyltransferase compare
MMP_RS04780 -1.5 -2.7 ribonuclease P compare


Specific Phenotypes

For 2 genes in this experiment

For nitrogen source L-Valine in Methanococcus maripaludis S2

For nitrogen source L-Valine across organisms