Experiment set10S132 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM Thymidine

200 most important genes:

  gene name fitness t score description  
MMP_RS08715 -6.0 -1.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS04710 -5.9 -2.2 hypothetical protein compare
MMP_RS06625 -5.7 -2.4 DNA primase compare
MMP_RS01020 -4.9 -1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS02675 -4.8 -2.6 hypothetical protein compare
MMP_RS07345 -4.6 -8.0 glycine synthesis protein GlyXL (from data) compare
MMP_RS01500 -4.5 -2.2 CBS domain-containing protein compare
MMP_RS03450 -4.5 -2.3 glycine synthesis protein GlyXS (from data) compare
MMP_RS07390 -4.5 -2.8 cell division protein FtsZ compare
MMP_RS00300 -4.5 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS02685 -4.5 -12.2 molybdate ABC transporter substrate-binding protein compare
MMP_RS04450 -4.4 -12.5 P-II family nitrogen regulator compare
MMP_RS04465 -4.4 -17.5 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS04460 -4.4 -20.6 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS03435 -4.4 -2.1 ketol-acid reductoisomerase compare
MMP_RS03700 -4.3 -10.4 sodium:proton antiporter compare
MMP_RS04090 -4.3 -3.3 hypothetical protein compare
MMP_RS02680 -4.3 -6.6 ABC transporter permease compare
MMP_RS06355 -4.3 -3.1 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS04470 -4.2 -16.7 nitrogenase compare
MMP_RS04455 -4.2 -21.4 nitrogenase subunit alpha compare
MMP_RS01385 -4.2 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS02670 -4.2 -13.5 ATP-binding cassette domain-containing protein compare
MMP_RS07635 -4.2 -9.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04445 -4.2 -7.9 P-II family nitrogen regulator compare
MMP_RS06285 -4.1 -2.6 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06915 -4.1 -6.8 metallophosphoesterase compare
MMP_RS08165 -4.0 -2.8 phosphoglycerate dehydrogenase compare
MMP_RS04890 -4.0 -0.9 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06400 -4.0 -1.7 4Fe-4S binding protein compare
MMP_RS08720 -3.9 -1.7 4Fe-4S binding protein compare
MMP_RS05930 -3.9 -2.4 3-isopropylmalate dehydratase large subunit compare
MMP_RS02010 -3.9 -8.4 PHP domain-containing protein compare
MMP_RS00555 -3.9 -7.6 MFS transporter compare
MMP_RS05345 -3.9 -9.6 hypothetical protein compare
MMP_RS04440 -3.9 -12.5 nitrogenase iron protein compare
MMP_RS01545 -3.8 -1.0 CBS domain-containing protein compare
MMP_RS01225 -3.8 -6.2 DUF5379 domain-containing protein compare
MMP_RS01325 -3.7 -2.2 dihydroneopterin aldolase family protein compare
MMP_RS05500 -3.7 -8.1 2-isopropylmalate synthase compare
MMP_RS04215 -3.7 -11.3 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS02355 -3.7 -2.7 30S ribosomal protein S27ae compare
MMP_RS02145 -3.6 -9.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS05250 -3.6 -1.8 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01175 -3.6 -4.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03035 -3.5 -4.0 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS06315 -3.5 -0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08435 -3.5 -2.5 Era-like GTP-binding protein compare
MMP_RS03960 -3.4 -1.6 hypothetical protein compare
MMP_RS01800 -3.4 -4.5 TIGR00303 family protein compare
MMP_RS00040 -3.4 -5.6 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS08940 -3.4 -1.3 MetS family NSS transporter small subunit compare
MMP_RS07525 -3.4 -9.5 4Fe-4S binding protein compare
MMP_RS00915 -3.4 -8.3 DUF116 domain-containing protein compare
MMP_RS06295 -3.4 -7.0 methanogenesis marker 14 protein compare
MMP_RS03110 -3.4 -8.6 glycosyltransferase family 2 protein compare
MMP_RS07185 -3.4 -12.8 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02730 -3.3 -11.6 ModD protein compare
MMP_RS03025 -3.3 -6.5 molybdenum cofactor guanylyltransferase compare
MMP_RS06020 -3.3 -5.0 archaeoflavoprotein AfpA compare
MMP_RS07365 -3.3 -13.7 2-phosphoglycerate kinase compare
MMP_RS06120 -3.2 -2.5 UPF0147 family protein compare
MMP_RS00455 -3.2 -7.9 orotate phosphoribosyltransferase-like protein compare
MMP_RS04780 -3.2 -3.4 ribonuclease P compare
MMP_RS03315 -3.2 -1.6 ferrous iron transport protein A compare
MMP_RS01220 -3.1 -8.8 hypothetical protein compare
MMP_RS08790 -3.1 -1.8 translation initiation factor IF-2 subunit alpha compare
MMP_RS01455 -3.1 -8.3 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS01795 -3.1 -1.6 methanogenesis marker 6 protein compare
MMP_RS02340 -3.1 -2.5 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08635 -3.1 -2.0 UbiA family prenyltransferase compare
MMP_RS06375 -3.1 -5.3 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS06270 -3.0 -5.8 TIGR00300 family protein compare
MMP_RS01830 -3.0 -1.7 tRNA-Val compare
MMP_RS06855 -3.0 -10.7 hypothetical protein compare
MMP_RS06920 -3.0 -13.7 AAA family ATPase compare
MMP_RS08860 -2.9 -6.2 MinD/ParA family protein compare
MMP_RS06630 -2.9 -0.9 UPF0058 family protein compare
MMP_RS08500 -2.9 -6.3 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS00310 -2.9 -12.1 CBS domain-containing protein compare
MMP_RS07710 -2.8 -7.5 cell division protein FtsZ compare
MMP_RS02175 -2.8 -0.9 DUF1611 domain-containing protein compare
MMP_RS04585 -2.8 -11.3 AIR synthase related protein compare
MMP_RS07075 -2.8 -3.9 phosphomannomutase/phosphoglucomutase compare
MMP_RS07355 -2.8 -0.8 transcription factor S compare
MMP_RS02240 -2.8 -3.5 methanogenesis marker 7 protein compare
MMP_RS01380 -2.7 -4.9 PHP domain-containing protein compare
MMP_RS06725 -2.7 -12.9 hypothetical protein compare
MMP_RS08645 -2.7 -6.9 UPF0179 family protein compare
MMP_RS06475 -2.7 -5.1 FAD-dependent oxidoreductase compare
MMP_RS03600 -2.7 -2.4 triose-phosphate isomerase compare
MMP_RS03485 -2.7 -4.7 TIGR00267 family protein compare
MMP_RS07445 -2.6 -6.2 helix-turn-helix domain-containing protein compare
MMP_RS05515 -2.6 -5.0 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS04685 -2.6 -2.6 DUF126 domain-containing protein compare
MMP_RS00725 -2.6 -7.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS03015 -2.6 -7.5 GTP 3' 8-cyclase MoaA compare
MMP_RS05920 -2.6 -0.5 50S ribosomal protein L37e compare
MMP_RS06230 -2.6 -2.3 helix-turn-helix domain-containing protein compare
MMP_RS08210 -2.6 -2.6 phosphatidylglycerophosphatase A compare
MMP_RS03445 -2.6 -1.0 methanogenesis marker 17 protein compare
MMP_RS08660 -2.6 -8.2 DHH family phosphoesterase compare
MMP_RS00735 -2.6 -3.5 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS05550 -2.6 -0.8 cation:proton antiporter compare
MMP_RS00810 -2.6 -8.0 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08650 -2.5 -3.6 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS07200 -2.5 -6.5 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06730 -2.5 -1.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS00730 -2.4 -4.4 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS04850 -2.4 -15.3 UPF0254 family protein compare
MMP_RS01725 -2.4 -3.9 class I SAM-dependent methyltransferase family protein compare
MMP_RS07380 -2.4 -2.0 transcription elongation factor Spt5 compare
MMP_RS07435 -2.4 -1.9 GMP synthase subunit A compare
MMP_RS05430 -2.4 -5.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS01610 -2.3 -2.6 hypothetical protein compare
MMP_RS05020 -2.3 -4.0 hypothetical protein compare
MMP_RS07605 -2.3 -3.0 diadenylate cyclase compare
MMP_RS00985 -2.3 -5.4 CDC48 family AAA ATPase compare
MMP_RS07535 -2.3 -10.6 4Fe-4S binding protein compare
MMP_RS02245 -2.3 -2.9 hypothetical protein compare
MMP_RS04790 -2.3 -11.2 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS01085 -2.2 -1.9 hypothetical protein compare
MMP_RS07845 -2.2 -2.2 LL-diaminopimelate aminotransferase compare
MMP_RS07545 -2.2 -0.9 HTH domain-containing protein compare
MMP_RS06370 -2.2 -5.2 biotin synthase BioB compare
MMP_RS04500 -2.2 -12.1 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS07700 -2.2 -9.4 DUF1188 domain-containing protein compare
MMP_RS07695 -2.2 -6.5 DUF3236 domain-containing protein compare
MMP_RS09020 -2.2 -1.6 hypothetical protein compare
MMP_RS06350 -2.2 -6.0 HesA/MoeB/ThiF family protein compare
MMP_RS07730 -2.2 -1.9 pyruvate synthase subunit beta compare
MMP_RS00685 -2.2 -3.4 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07575 -2.1 -3.9 RNA ligase partner protein compare
MMP_RS01925 -2.1 -7.8 DUF1616 domain-containing protein compare
MMP_RS06925 -2.1 -2.5 ribonuclease VapC4 compare
MMP_RS00900 -2.1 -1.6 50S ribosomal protein L39e compare
MMP_RS05640 -2.1 -6.3 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS01875 -2.1 -7.5 N-acetyltransferase compare
MMP_RS05265 -2.1 -2.0 2-isopropylmalate synthase compare
MMP_RS05925 -2.1 -3.9 small nuclear ribonucleoprotein compare
MMP_RS01755 -2.1 -0.9 DUF2097 domain-containing protein compare
MMP_RS07705 -2.0 -6.3 transcriptional regulator compare
MMP_RS06395 -2.0 -3.5 ThiF family adenylyltransferase compare
MMP_RS08155 -2.0 -6.5 hypothetical protein compare
MMP_RS08440 -2.0 -2.5 cell division protein SepF compare
MMP_RS08855 -2.0 -7.5 hypothetical protein compare
MMP_RS02195 -2.0 -3.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01265 -2.0 -2.4 hypothetical protein compare
MMP_RS06670 -2.0 -4.9 glucose-6-phosphate isomerase compare
MMP_RS07735 -2.0 -0.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05535 -1.9 -3.5 hypothetical protein compare
MMP_RS08570 -1.9 -9.0 coenzyme F420-0:L-glutamate ligase compare
MMP_RS08195 -1.9 -7.8 hypothetical protein compare
MMP_RS01900 -1.9 -10.8 hypothetical protein compare
MMP_RS08460 -1.9 -2.3 proteasome-activating nucleotidase compare
MMP_RS00710 -1.9 -4.0 hypothetical protein compare
MMP_RS03205 -1.9 -1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02190 -1.9 -2.7 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS07755 -1.9 -1.1 DUF555 domain-containing protein compare
MMP_RS00305 -1.9 -1.4 phosphoribosyl-ATP diphosphatase compare
MMP_RS06015 -1.9 -4.3 flavodoxin family protein compare
MMP_RS00520 -1.9 -1.6 RNA polymerase Rpb4 family protein compare
MMP_RS05425 -1.9 -4.3 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS04955 -1.9 -4.2 DNA topoisomerase I compare
MMP_RS00035 -1.8 -5.4 DUF2098 family protein compare
MMP_RS05280 -1.8 -7.6 COG1361 S-layer family protein compare
MMP_RS02225 -1.8 -4.9 carbohydrate kinase family protein compare
MMP_RS06895 -1.8 -1.7 selenocysteine-specific translation elongation factor compare
MMP_RS00570 -1.8 -1.4 protein-L-isoaspartate O-methyltransferase compare
MMP_RS01195 -1.8 -1.1 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS00320 -1.8 -1.6 class I SAM-dependent methyltransferase compare
MMP_RS01885 -1.8 -6.0 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS08300 -1.8 -0.8 metal-sulfur cluster assembly factor compare
MMP_RS04605 -1.8 -3.9 cobalt ECF transporter T component CbiQ compare
MMP_RS00750 -1.8 -1.7 fumarate hydratase compare
MMP_RS02345 -1.8 -2.8 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03640 -1.8 -2.9 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS02280 -1.8 -0.7 DUF211 domain-containing protein compare
MMP_RS06175 -1.7 -5.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS07005 -1.7 -0.5 4Fe-4S binding protein compare
MMP_RS01720 -1.7 -1.5 replication factor C large subunit compare
MMP_RS03420 -1.7 -3.1 acetolactate synthase small subunit compare
MMP_RS06970 -1.7 -5.9 ribosomal protein S18-alanine N-acetyltransferase compare
MMP_RS02780 -1.7 -5.4 hypothetical protein compare
MMP_RS07600 -1.7 -2.0 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS09055 -1.6 -0.8 CAP domain-containing protein compare
MMP_RS05540 -1.6 -2.3 hypothetical protein compare
MMP_RS05765 -1.6 -3.8 M42 family metallopeptidase compare
MMP_RS07555 -1.6 -0.7 monovalent cation/H+ antiporter subunit E compare
MMP_RS07090 -1.6 -6.4 tRNA (adenine-N1)-methyltransferase compare
MMP_RS03550 -1.6 -1.7 DUF2124 domain-containing protein compare
MMP_RS05875 -1.6 -2.9 hydroxyethylthiazole kinase compare
MMP_RS07180 -1.6 -4.7 DEAD/DEAH box helicase compare
MMP_RS03580 -1.6 -2.5 signal recognition particle-docking protein FtsY compare
MMP_RS05845 -1.6 -1.1 tRNA-intron lyase compare
MMP_RS00130 -1.6 -1.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS04870 -1.6 -4.9 TIGR02253 family HAD-type hydrolase compare
MMP_RS02165 -1.6 -4.5 tRNA-dihydrouridine synthase compare
MMP_RS08330 -1.6 -4.6 NADH-quinone oxidoreductase subunit H compare
MMP_RS08745 -1.6 -4.0 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare


Specific Phenotypes

For 5 genes in this experiment

For nitrogen source Thymidine in Methanococcus maripaludis S2

For nitrogen source Thymidine across organisms