Experiment set10S115 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS03960		-3.7	-1.2	hypothetical protein
MMP_RS08715		-3.1	-1.5	formylmethanofuran dehydrogenase subunit B
MMP_RS01325		-2.9	-1.8	dihydroneopterin aldolase family protein
MMP_RS02900		-2.6	-0.4	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS01500		-2.4	-2.1	CBS domain-containing protein
MMP_RS03015		-2.4	-8.6	GTP 3' 8-cyclase MoaA
MMP_RS02280		-2.3	-0.6	DUF211 domain-containing protein
MMP_RS01020		-2.3	-0.8	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03035		-2.3	-2.6	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS02675		-2.3	-2.5	hypothetical protein
MMP_RS03300		-2.1	-0.6	TOBE domain-containing protein
MMP_RS06285		-2.1	-2.1	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS00685		-2.1	-3.2	2-phospho-L-lactate guanylyltransferase
MMP_RS03435		-2.1	-1.4	ketol-acid reductoisomerase
MMP_RS08650		-2.1	-2.3	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS07860		-2.0	-0.7	hypothetical protein
MMP_RS01225		-2.0	-4.5	DUF5379 domain-containing protein
MMP_RS05250		-2.0	-1.0	NFYB/HAP3 family transcription factor subunit
MMP_RS00300		-2.0	-0.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS02790		-2.0	-0.8	class III signal peptide-containing protein
MMP_RS08720		-1.9	-1.1	4Fe-4S binding protein
MMP_RS04450		-1.9	-8.6	P-II family nitrogen regulator
MMP_RS04465		-1.9	-11.5	nitrogenase iron-molybdenum cofactor biosynthesis protein NifE
MMP_RS07635		-1.9	-6.4	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS02345		-1.9	-2.5	GTP-dependent dephospho-CoA kinase family protein
MMP_RS04455		-1.8	-13.0	nitrogenase subunit alpha
MMP_RS06900		-1.8	-2.0	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS05540		-1.8	-4.8	hypothetical protein
MMP_RS03485		-1.8	-3.8	TIGR00267 family protein
MMP_RS03110		-1.8	-5.4	glycosyltransferase family 2 protein
MMP_RS06355		-1.8	-1.7	molybdenum cofactor biosynthesis protein MoaE
MMP_RS05850		-1.8	-3.0	Ldh family oxidoreductase
MMP_RS01005		-1.8	-0.9	riboflavin synthase
MMP_RS01700		-1.8	-0.5	dihydroxy-acid dehydratase
MMP_RS02010		-1.8	-8.5	PHP domain-containing protein
MMP_RS07700		-1.7	-8.5	DUF1188 domain-containing protein
MMP_RS06120		-1.7	-1.4	UPF0147 family protein
MMP_RS04870		-1.7	-4.0	TIGR02253 family HAD-type hydrolase
MMP_RS04780		-1.7	-2.3	ribonuclease P
MMP_RS04445		-1.7	-5.9	P-II family nitrogen regulator
MMP_RS07730		-1.7	-1.3	pyruvate synthase subunit beta
MMP_RS01175		-1.7	-3.3	triphosphoribosyl-dephospho-CoA synthase
MMP_RS04440		-1.7	-7.2	nitrogenase iron protein
MMP_RS04470		-1.7	-11.6	nitrogenase
MMP_RS06600		-1.7	-0.8	class III signal peptide-containing protein
MMP_RS06895		-1.7	-1.2	selenocysteine-specific translation elongation factor
MMP_RS07845		-1.7	-1.5	LL-diaminopimelate aminotransferase
MMP_RS06020		-1.7	-2.9	archaeoflavoprotein AfpA
MMP_RS02670		-1.7	-7.9	ATP-binding cassette domain-containing protein
MMP_RS06110		-1.7	-2.1	ATP-dependent protease LonB
MMP_RS03315		-1.7	-0.9	ferrous iron transport protein A
MMP_RS03235		-1.6	-4.4	tRNA pseudouridine(13) synthase TruD
MMP_RS00040		-1.6	-4.3	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS02685		-1.6	-7.8	molybdate ABC transporter substrate-binding protein
MMP_RS04850		-1.6	-12.3	UPF0254 family protein
MMP_RS02805		-1.6	-0.8	HEPN domain-containing protein
MMP_RS00725		-1.6	-4.9	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS07345		-1.6	-4.3	glycine synthesis protein GlyXL (from data)
MMP_RS01445		-1.6	-5.8	hypothetical protein
MMP_RS06015		-1.6	-5.2	flavodoxin family protein
MMP_RS04955		-1.6	-5.5	DNA topoisomerase I
MMP_RS05550		-1.6	-0.5	cation:proton antiporter
MMP_RS07620		-1.5	-3.1	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS02145		-1.5	-6.1	winged helix-turn-helix transcriptional regulator
MMP_RS01830		-1.5	-1.1	tRNA-Val
MMP_RS07555		-1.5	-0.5	monovalent cation/H+ antiporter subunit E
MMP_RS03320		-1.5	-2.2	metal-dependent transcriptional regulator
MMP_RS04460		-1.5	-11.3	nitrogenase molybdenum-iron protein subunit beta
MMP_RS05500		-1.5	-5.4	2-isopropylmalate synthase
MMP_RS07755		-1.5	-0.8	DUF555 domain-containing protein
MMP_RS05695		-1.5	-6.1	phospholipase D-like domain-containing protein
MMP_RS03450		-1.5	-1.3	glycine synthesis protein GlyXS (from data)
MMP_RS00315		-1.5	-3.8	Nif3-like dinuclear metal center hexameric protein
MMP_RS07750		-1.5	-2.9	DUF357 domain-containing protein
MMP_RS07445		-1.5	-6.0	helix-turn-helix domain-containing protein
MMP_RS02680		-1.5	-4.6	ABC transporter permease
MMP_RS07525		-1.5	-6.9	4Fe-4S binding protein
MMP_RS02730		-1.5	-5.8	ModD protein
MMP_RS02355		-1.5	-2.0	30S ribosomal protein S27ae
MMP_RS07705		-1.5	-7.1	transcriptional regulator
MMP_RS07355		-1.5	-0.5	transcription factor S
MMP_RS08940		-1.5	-0.7	MetS family NSS transporter small subunit
MMP_RS05515		-1.5	-4.7	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS07135		-1.5	-7.0	coenzyme F420 hydrogenase subunit beta
MMP_RS08300		-1.5	-0.5	metal-sulfur cluster assembly factor
MMP_RS04720		-1.5	-1.9	DedA family protein
MMP_RS00520		-1.5	-1.2	RNA polymerase Rpb4 family protein
MMP_RS03600		-1.5	-1.3	triose-phosphate isomerase
MMP_RS08705		-1.4	-4.3	sulfopyruvate decarboxylase subunit beta
MMP_RS08675		-1.4	-1.7	class III signal peptide-containing protein
MMP_RS04890		-1.4	-0.6	adenylyltransferase/cytidyltransferase family protein
MMP_RS06395		-1.4	-1.9	ThiF family adenylyltransferase
MMP_RS09020		-1.4	-0.9	hypothetical protein
MMP_RS00455		-1.4	-5.3	orotate phosphoribosyltransferase-like protein
MMP_RS01220		-1.4	-4.4	hypothetical protein
MMP_RS03580		-1.4	-1.9	signal recognition particle-docking protein FtsY
MMP_RS08860		-1.4	-3.7	MinD/ParA family protein
MMP_RS08100		-1.4	-4.5	8-amino-7-oxononanoate synthase
MMP_RS07390		-1.4	-1.6	cell division protein FtsZ
MMP_RS04090		-1.4	-1.7	hypothetical protein
MMP_RS06035		-1.4	-7.5	glycosyltransferase family 2 protein
MMP_RS03025		-1.4	-3.1	molybdenum cofactor guanylyltransferase
MMP_RS05635		-1.4	-5.1	NAD-dependent epimerase/dehydratase family protein
MMP_RS00730		-1.4	-2.9	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS07075		-1.4	-2.3	phosphomannomutase/phosphoglucomutase
MMP_RS03800		-1.3	-2.4	hypothetical protein
MMP_RS08930		-1.3	-1.0	hypothetical protein
MMP_RS08210		-1.3	-1.3	phosphatidylglycerophosphatase A
MMP_RS01380		-1.3	-2.9	PHP domain-containing protein
MMP_RS07415		-1.3	-4.0	molybdopterin-guanine dinucleotide biosynthesis protein MobB
MMP_RS06215		-1.3	-1.5	30S ribosomal protein S6e
MMP_RS07200		-1.3	-3.7	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS03700		-1.3	-5.5	sodium:proton antiporter
MMP_RS01250		-1.3	-2.3	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS05925		-1.3	-1.9	small nuclear ribonucleoprotein
MMP_RS07695		-1.3	-4.2	DUF3236 domain-containing protein
MMP_RS00735		-1.3	-1.9	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS06475		-1.3	-2.9	FAD-dependent oxidoreductase
MMP_RS05640		-1.3	-4.8	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS00555		-1.3	-5.0	MFS transporter
MMP_RS07630		-1.3	-0.7	ATP-binding cassette domain-containing protein
MMP_RS05930		-1.3	-1.3	3-isopropylmalate dehydratase large subunit
MMP_RS00035		-1.3	-5.9	DUF2098 family protein
MMP_RS01880		-1.3	-4.9	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS01885		-1.3	-5.9	Gfo/Idh/MocA family oxidoreductase
MMP_RS07435		-1.3	-0.9	GMP synthase subunit A
MMP_RS06350		-1.3	-4.1	HesA/MoeB/ThiF family protein
MMP_RS03340		-1.3	-0.5	ABC transporter ATP-binding protein
MMP_RS05675		-1.3	-1.7	phosphate ABC transporter ATP-binding protein PstB
MMP_RS07605		-1.3	-2.2	diadenylate cyclase
MMP_RS04775		-1.3	-1.6	adenosylhomocysteinase
MMP_RS03535		-1.2	-1.8	helix-turn-helix transcriptional regulator
MMP_RS08855		-1.2	-4.7	hypothetical protein
MMP_RS01335		-1.2	-1.2	prefoldin subunit beta
MMP_RS05110		-1.2	-2.9	16S ribosomal RNA methyltransferase A
MMP_RS07380		-1.2	-1.2	transcription elongation factor Spt5
MMP_RS02310		-1.2	-0.8	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS05535		-1.2	-3.3	hypothetical protein
MMP_RS06625		-1.2	-1.2	DNA primase
MMP_RS07575		-1.2	-2.4	RNA ligase partner protein
MMP_RS01925		-1.2	-5.5	DUF1616 domain-containing protein
MMP_RS05255		-1.2	-6.7	CBS domain-containing protein
MMP_RS08660		-1.2	-4.4	DHH family phosphoesterase
MMP_RS00545		-1.2	-2.3	XRE family transcriptional regulator
MMP_RS03540		-1.2	-3.4	DUF2178 domain-containing protein
MMP_RS00130		-1.2	-0.6	nickel-responsive transcriptional regulator NikR
MMP_RS07330		-1.2	-8.9	membrane protein
MMP_RS02895		-1.2	-4.6	DHH family phosphoesterase
MMP_RS02290		-1.2	-3.8	MBL fold metallo-hydrolase
MMP_RS01875		-1.2	-5.4	N-acetyltransferase
MMP_RS05985		-1.2	-1.9	hypothetical protein
MMP_RS02240		-1.2	-1.4	methanogenesis marker 7 protein
MMP_RS01455		-1.2	-3.3	nickel pincer cofactor biosynthesis protein LarC
MMP_RS04305		-1.2	-1.0	hypothetical protein
MMP_RS02165		-1.2	-4.4	tRNA-dihydrouridine synthase
MMP_RS04500		-1.2	-6.5	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS08645		-1.2	-4.3	UPF0179 family protein
MMP_RS07385		-1.1	-1.4	protein translocase SEC61 complex subunit gamma
MMP_RS02020		-1.1	-1.7	gamma-glutamylcyclotransferase
MMP_RS06725		-1.1	-5.8	hypothetical protein
MMP_RS01180		-1.1	-1.2	XTP/dITP diphosphatase
MMP_RS07535		-1.1	-5.2	4Fe-4S binding protein
MMP_RS06855		-1.1	-5.9	hypothetical protein
MMP_RS07710		-1.1	-4.9	cell division protein FtsZ
MMP_RS00665		-1.1	-2.6	hypothetical protein
MMP_RS01960		-1.1	-0.4	hypothetical protein
MMP_RS02245		-1.1	-1.8	hypothetical protein
MMP_RS06290		-1.1	-2.2	DNA repair and recombination protein RadA
MMP_RS00675		-1.1	-0.5	nitroreductase family protein
MMP_RS07120		-1.1	-3.0	coenzyme F420 hydrogenase subunit alpha
MMP_RS01795		-1.1	-0.7	methanogenesis marker 6 protein
MMP_RS03305		-1.1	-2.9	winged helix-turn-helix domain-containing protein
MMP_RS04195		-1.1	-1.5	flavodoxin
MMP_RS03090		-1.1	-4.3	cation:proton antiporter
MMP_RS08750		-1.1	-1.1	hypothetical protein
MMP_RS01900		-1.0	-7.1	hypothetical protein
MMP_RS03890		-1.0	-2.3	DUF2540 domain-containing protein
MMP_RS05265		-1.0	-1.0	2-isopropylmalate synthase
MMP_RS01280		-1.0	-5.7	DUF515 domain-containing protein
MMP_RS03385		-1.0	-0.6	cation diffusion facilitator family transporter
MMP_RS01270		-1.0	-6.7	prepilin peptidase
MMP_RS07090		-1.0	-5.5	tRNA (adenine-N1)-methyltransferase
MMP_RS01965		-1.0	-1.8	DUF1616 domain-containing protein
MMP_RS06710		-1.0	-2.1	selenium-binding protein
MMP_RS05285		-1.0	-2.8	MMPL family transporter
MMP_RS06840		-1.0	-0.4	DNA-directed RNA polymerase subunit N
MMP_RS04900		-1.0	-6.3	hypothetical protein
MMP_RS01775		-1.0	-0.8	TIGR00297 family protein
MMP_RS05295		-1.0	-4.4	minichromosome maintenance protein MCM
MMP_RS03910		-1.0	-1.1	hypothetical protein
MMP_RS01655		-1.0	-1.7	DsrE family protein
MMP_RS06485		-1.0	-0.4	zinc ribbon domain-containing protein
MMP_RS05425		-1.0	-2.4	monovalent cation/H+ antiporter complex subunit F
MMP_RS00905		-1.0	-1.2	phenylacetate--CoA ligase
MMP_RS07955		-1.0	-1.5	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS01790		-1.0	-2.6	restriction endonuclease
MMP_RS01905		-1.0	-5.9	glycosyltransferase
MMP_RS00120		-1.0	-2.0	LysR family transcriptional regulator
MMP_RS02955		-1.0	-1.4	DJ-1/PfpI family protein
MMP_RS01305		-1.0	-6.9	hypothetical protein

Specific Phenotypes

For 3 genes in this experiment

For nitrogen source L-tyrosine disodium salt in Methanococcus maripaludis S2

For nitrogen source L-tyrosine disodium salt across organisms