Experiment set10S112 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Leucine

200 most important genes:

  gene name fitness t score description  
MMP_RS01500 -6.5 -2.7 CBS domain-containing protein compare
MMP_RS02355 -5.9 -3.7 30S ribosomal protein S27ae compare
MMP_RS07345 -5.8 -9.2 glycine synthesis protein GlyXL (from data) compare
MMP_RS01175 -5.0 -6.1 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS00555 -4.9 -9.8 MFS transporter compare
MMP_RS04460 -4.8 -20.3 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS04450 -4.8 -14.5 P-II family nitrogen regulator compare
MMP_RS07185 -4.8 -15.5 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS04470 -4.7 -20.3 nitrogenase compare
MMP_RS04465 -4.7 -19.3 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS02670 -4.7 -12.9 ATP-binding cassette domain-containing protein compare
MMP_RS03035 -4.6 -4.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02010 -4.6 -11.5 PHP domain-containing protein compare
MMP_RS06625 -4.6 -3.1 DNA primase compare
MMP_RS04445 -4.6 -10.6 P-II family nitrogen regulator compare
MMP_RS04440 -4.6 -12.7 nitrogenase iron protein compare
MMP_RS08165 -4.6 -2.4 phosphoglycerate dehydrogenase compare
MMP_RS04455 -4.6 -23.7 nitrogenase subunit alpha compare
MMP_RS01020 -4.5 -1.3 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00750 -4.5 -2.7 fumarate hydratase compare
MMP_RS07845 -4.3 -2.6 LL-diaminopimelate aminotransferase compare
MMP_RS02685 -4.3 -14.1 molybdate ABC transporter substrate-binding protein compare
MMP_RS00040 -4.3 -7.6 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06475 -4.3 -5.1 FAD-dependent oxidoreductase compare
MMP_RS02675 -4.3 -3.5 hypothetical protein compare
MMP_RS07730 -4.2 -2.3 pyruvate synthase subunit beta compare
MMP_RS03435 -4.2 -2.6 ketol-acid reductoisomerase compare
MMP_RS00915 -4.2 -10.0 DUF116 domain-containing protein compare
MMP_RS07005 -4.2 -0.6 4Fe-4S binding protein compare
MMP_RS03445 -4.1 -1.2 methanogenesis marker 17 protein compare
MMP_RS09020 -4.1 -2.2 hypothetical protein compare
MMP_RS07635 -4.1 -10.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS05265 -4.0 -2.7 2-isopropylmalate synthase compare
MMP_RS06400 -4.0 -2.2 4Fe-4S binding protein compare
MMP_RS01800 -3.9 -5.2 TIGR00303 family protein compare
MMP_RS01610 -3.9 -4.0 hypothetical protein compare
MMP_RS04890 -3.9 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01225 -3.9 -5.4 DUF5379 domain-containing protein compare
MMP_RS02245 -3.9 -3.9 hypothetical protein compare
MMP_RS07355 -3.8 -1.0 transcription factor S compare
MMP_RS02730 -3.8 -12.8 ModD protein compare
MMP_RS07525 -3.8 -10.7 4Fe-4S binding protein compare
MMP_RS04710 -3.7 -2.5 hypothetical protein compare
MMP_RS00685 -3.7 -5.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS08860 -3.7 -6.2 MinD/ParA family protein compare
MMP_RS00455 -3.6 -10.6 orotate phosphoribosyltransferase-like protein compare
MMP_RS03580 -3.6 -5.0 signal recognition particle-docking protein FtsY compare
MMP_RS01325 -3.6 -3.0 dihydroneopterin aldolase family protein compare
MMP_RS03025 -3.6 -8.0 molybdenum cofactor guanylyltransferase compare
MMP_RS02680 -3.5 -9.5 ABC transporter permease compare
MMP_RS02240 -3.5 -4.2 methanogenesis marker 7 protein compare
MMP_RS01455 -3.5 -8.4 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS06270 -3.5 -5.4 TIGR00300 family protein compare
MMP_RS02145 -3.5 -11.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS07380 -3.5 -2.4 transcription elongation factor Spt5 compare
MMP_RS03450 -3.3 -2.9 glycine synthesis protein GlyXS (from data) compare
MMP_RS07390 -3.3 -3.7 cell division protein FtsZ compare
MMP_RS03315 -3.3 -1.9 ferrous iron transport protein A compare
MMP_RS02175 -3.3 -1.1 DUF1611 domain-containing protein compare
MMP_RS03700 -3.3 -11.5 sodium:proton antiporter compare
MMP_RS04585 -3.2 -15.4 AIR synthase related protein compare
MMP_RS05925 -3.2 -4.6 small nuclear ribonucleoprotein compare
MMP_RS08715 -3.2 -2.6 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06020 -3.2 -6.2 archaeoflavoprotein AfpA compare
MMP_RS01005 -3.2 -1.2 riboflavin synthase compare
MMP_RS08500 -3.2 -7.2 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS08790 -3.2 -2.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS04215 -3.2 -8.7 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS01725 -3.2 -5.9 class I SAM-dependent methyltransferase family protein compare
MMP_RS08645 -3.1 -8.4 UPF0179 family protein compare
MMP_RS05920 -3.1 -0.6 50S ribosomal protein L37e compare
MMP_RS04090 -3.1 -2.7 hypothetical protein compare
MMP_RS05845 -3.1 -1.9 tRNA-intron lyase compare
MMP_RS04685 -3.1 -3.6 DUF126 domain-containing protein compare
MMP_RS05430 -3.1 -6.3 TIGR00288 family NYN domain-containing protein compare
MMP_RS00735 -3.1 -4.3 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS07555 -3.0 -1.1 monovalent cation/H+ antiporter subunit E compare
MMP_RS01795 -3.0 -1.7 methanogenesis marker 6 protein compare
MMP_RS03640 -3.0 -5.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06285 -3.0 -2.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03110 -3.0 -7.8 glycosyltransferase family 2 protein compare
MMP_RS07365 -3.0 -13.0 2-phosphoglycerate kinase compare
MMP_RS07445 -2.9 -7.1 helix-turn-helix domain-containing protein compare
MMP_RS01830 -2.9 -2.0 tRNA-Val compare
MMP_RS08720 -2.9 -2.0 4Fe-4S binding protein compare
MMP_RS07955 -2.9 -5.6 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS05930 -2.9 -2.6 3-isopropylmalate dehydratase large subunit compare
MMP_RS00310 -2.8 -8.9 CBS domain-containing protein compare
MMP_RS07200 -2.8 -8.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00895 -2.8 -5.0 hypothetical protein compare
MMP_RS03600 -2.8 -2.9 triose-phosphate isomerase compare
MMP_RS06725 -2.8 -14.9 hypothetical protein compare
MMP_RS07605 -2.8 -4.3 diadenylate cyclase compare
MMP_RS03960 -2.8 -2.0 hypothetical protein compare
MMP_RS08435 -2.8 -2.5 Era-like GTP-binding protein compare
MMP_RS06375 -2.7 -6.2 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS01385 -2.7 -0.8 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS05345 -2.7 -10.0 hypothetical protein compare
MMP_RS01380 -2.7 -5.0 PHP domain-containing protein compare
MMP_RS04850 -2.7 -19.0 UPF0254 family protein compare
MMP_RS02900 -2.7 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01265 -2.7 -2.7 hypothetical protein compare
MMP_RS00900 -2.6 -2.7 50S ribosomal protein L39e compare
MMP_RS01220 -2.6 -9.0 hypothetical protein compare
MMP_RS03440 -2.6 -1.6 MoaD/ThiS family protein compare
MMP_RS00730 -2.6 -7.7 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01085 -2.6 -2.4 hypothetical protein compare
MMP_RS00985 -2.6 -4.2 CDC48 family AAA ATPase compare
MMP_RS04790 -2.6 -10.8 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS00810 -2.6 -9.9 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS06885 -2.6 -3.0 50S ribosome-binding GTPase compare
MMP_RS06855 -2.5 -10.2 hypothetical protein compare
MMP_RS06120 -2.5 -2.5 UPF0147 family protein compare
MMP_RS01875 -2.5 -12.7 N-acetyltransferase compare
MMP_RS02195 -2.5 -4.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS06975 -2.5 -2.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07700 -2.5 -11.9 DUF1188 domain-containing protein compare
MMP_RS00725 -2.5 -8.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS08785 -2.5 -1.4 RNA-protein complex protein Nop10 compare
MMP_RS04870 -2.5 -5.5 TIGR02253 family HAD-type hydrolase compare
MMP_RS02340 -2.5 -2.5 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07545 -2.4 -1.1 HTH domain-containing protein compare
MMP_RS03475 -2.4 -0.7 hypothetical protein compare
MMP_RS02345 -2.4 -3.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS00300 -2.4 -0.8 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS04615 -2.4 -4.5 PDGLE domain-containing protein compare
MMP_RS08650 -2.4 -4.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS05250 -2.3 -2.2 NFYB/HAP3 family transcription factor subunit compare
MMP_RS00520 -2.3 -1.8 RNA polymerase Rpb4 family protein compare
MMP_RS03205 -2.3 -2.1 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07075 -2.3 -3.7 phosphomannomutase/phosphoglucomutase compare
MMP_RS06230 -2.3 -2.7 helix-turn-helix domain-containing protein compare
MMP_RS04780 -2.3 -3.5 ribonuclease P compare
MMP_RS07695 -2.3 -6.1 DUF3236 domain-containing protein compare
MMP_RS08570 -2.3 -9.5 coenzyme F420-0:L-glutamate ligase compare
MMP_RS02800 -2.3 -4.5 nucleotidyltransferase domain-containing protein compare
MMP_RS05425 -2.2 -6.2 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06295 -2.2 -4.7 methanogenesis marker 14 protein compare
MMP_RS05020 -2.2 -4.2 hypothetical protein compare
MMP_RS07600 -2.2 -3.0 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08155 -2.2 -7.3 hypothetical protein compare
MMP_RS04900 -2.2 -14.4 hypothetical protein compare
MMP_RS03090 -2.2 -7.4 cation:proton antiporter compare
MMP_RS08210 -2.2 -2.2 phosphatidylglycerophosphatase A compare
MMP_RS01755 -2.2 -1.0 DUF2097 domain-containing protein compare
MMP_RS04955 -2.2 -6.1 DNA topoisomerase I compare
MMP_RS06355 -2.2 -3.7 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03420 -2.2 -3.7 acetolactate synthase small subunit compare
MMP_RS01885 -2.1 -8.4 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS02780 -2.1 -6.1 hypothetical protein compare
MMP_RS01445 -2.1 -9.4 hypothetical protein compare
MMP_RS07575 -2.1 -4.7 RNA ligase partner protein compare
MMP_RS08820 -2.1 -5.4 hypothetical protein compare
MMP_RS01880 -2.1 -7.2 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS06105 -2.1 -7.3 hydrogenase maturation peptidase HycI compare
MMP_RS07535 -2.1 -8.3 4Fe-4S binding protein compare
MMP_RS08195 -2.0 -8.8 hypothetical protein compare
MMP_RS06395 -2.0 -3.2 ThiF family adenylyltransferase compare
MMP_RS05460 -2.0 -9.7 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS08440 -2.0 -2.7 cell division protein SepF compare
MMP_RS00315 -2.0 -7.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS04500 -2.0 -12.3 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06630 -2.0 -0.9 UPF0058 family protein compare
MMP_RS00110 -1.9 -3.1 hypothetical protein compare
MMP_RS07710 -1.9 -7.2 cell division protein FtsZ compare
MMP_RS06895 -1.9 -1.7 selenocysteine-specific translation elongation factor compare
MMP_RS08855 -1.9 -8.5 hypothetical protein compare
MMP_RS02875 -1.9 -6.7 chorismate pyruvate-lyase family protein compare
MMP_RS08300 -1.9 -1.0 metal-sulfur cluster assembly factor compare
MMP_RS05540 -1.9 -1.8 hypothetical protein compare
MMP_RS08660 -1.9 -7.6 DHH family phosphoesterase compare
MMP_RS06925 -1.8 -2.8 ribonuclease VapC4 compare
MMP_RS01890 -1.8 -5.0 nucleotide sugar dehydrogenase compare
MMP_RS00515 -1.8 -0.9 DUF655 domain-containing protein compare
MMP_RS03140 -1.8 -7.3 hypothetical protein compare
MMP_RS05440 -1.8 -8.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS00115 -1.8 -9.0 radical SAM protein compare
MMP_RS05640 -1.8 -5.7 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS06670 -1.8 -5.4 glucose-6-phosphate isomerase compare
MMP_RS07750 -1.8 -4.8 DUF357 domain-containing protein compare
MMP_RS00035 -1.8 -5.3 DUF2098 family protein compare
MMP_RS01195 -1.8 -1.2 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS08705 -1.8 -5.7 sulfopyruvate decarboxylase subunit beta compare
MMP_RS00305 -1.7 -1.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS02165 -1.7 -6.4 tRNA-dihydrouridine synthase compare
MMP_RS08225 -1.7 -8.6 RimK family alpha-L-glutamate ligase compare
MMP_RS05545 -1.7 -4.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02110 -1.7 -1.9 hypothetical protein compare
MMP_RS07090 -1.7 -6.5 tRNA (adenine-N1)-methyltransferase compare
MMP_RS04720 -1.7 -2.2 DedA family protein compare
MMP_RS06370 -1.6 -4.0 biotin synthase BioB compare
MMP_RS01900 -1.6 -9.9 hypothetical protein compare
MMP_RS08330 -1.6 -6.1 NADH-quinone oxidoreductase subunit H compare
MMP_RS06730 -1.6 -1.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS08635 -1.6 -1.4 UbiA family prenyltransferase compare
MMP_RS01365 -1.6 -2.0 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS03390 -1.6 -5.7 malate dehydrogenase compare
MMP_RS05535 -1.6 -3.6 hypothetical protein compare
MMP_RS08995 -1.6 -1.4 hypothetical protein compare
MMP_RS03485 -1.5 -3.1 TIGR00267 family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nitrogen source experiments

For nitrogen source L-Leucine across organisms