Experiment set10S110 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Valine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS08320 +2.5 8.5 molybdopterin molybdotransferase MoeA compare
MMP_RS02885 +2.3 11.7 molybdopterin biosynthesis protein compare
MMP_RS00325 +1.9 3.1 RNA-binding protein compare
MMP_RS02290 +1.7 9.4 MBL fold metallo-hydrolase compare
MMP_RS04885 +1.5 8.4 sulfite exporter TauE/SafE family protein compare
MMP_RS00185 +1.3 8.1 potassium channel protein compare
MMP_RS06720 +1.3 5.7 response regulator transcription factor compare
MMP_RS08310 +1.3 2.3 TMEM165/GDT1 family protein compare
MMP_RS06540 +1.2 2.4 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS07840 +1.2 1.7 ribonuclease III compare
MMP_RS06715 +1.2 6.3 cache domain-containing protein compare
MMP_RS05975 +1.1 1.6 hypothetical protein compare
MMP_RS00395 +1.1 1.5 MGMT family protein compare
MMP_RS00855 +1.0 3.7 DUF367 family protein compare
MMP_RS06545 +1.0 2.0 ferredoxin family protein compare
MMP_RS01685 +1.0 2.6 indolepyruvate oxidoreductase subunit beta compare
MMP_RS03465 +1.0 1.2 adenine phosphoribosyltransferase compare
MMP_RS08725 +0.9 0.8 Ni/Fe hydrogenase subunit alpha compare
MMP_RS05695 +0.9 4.4 phospholipase D-like domain-containing protein compare
MMP_RS00660 +0.9 5.0 alkaline phosphatase family protein compare
MMP_RS05110 +0.9 4.6 16S ribosomal RNA methyltransferase A compare
MMP_RS00345 +0.9 2.2 DUF2666 domain-containing protein compare
MMP_RS05355 +0.9 0.6 hypothetical protein compare
MMP_RS07915 +0.9 3.3 DUF4870 domain-containing protein compare
MMP_RS00430 +0.9 1.9 hypothetical protein compare
MMP_RS06870 +0.9 4.3 DedA family protein compare
MMP_RS05795 +0.9 2.1 redox-regulated ATPase YchF compare
MMP_RS08760 +0.8 2.1 hypothetical protein compare
MMP_RS04800 +0.8 3.7 chemotaxis protein CheW compare
MMP_RS08350 +0.8 0.8 hypothetical protein compare
MMP_RS00295 +0.8 1.7 gamma carbonic anhydrase family protein compare
MMP_RS08260 +0.8 2.5 DUF99 family protein compare
MMP_RS00960 +0.8 1.5 iron export ABC transporter permease subunit FetB compare
MMP_RS06485 +0.8 0.6 zinc ribbon domain-containing protein compare
MMP_RS02045 +0.8 1.1 tRNA-Met compare
MMP_RS01495 +0.8 3.8 TraB/GumN family protein compare
MMP_RS02390 +0.8 3.4 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS02310 +0.8 1.1 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS01055 +0.8 2.3 hypothetical protein compare
MMP_RS07125 +0.8 2.1 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00130 +0.8 0.8 nickel-responsive transcriptional regulator NikR compare
MMP_RS01630 +0.8 3.0 N-glycosylase/DNA lyase compare
MMP_RS03150 +0.8 4.0 phosphoglycerate mutase compare
MMP_RS03320 +0.8 1.3 metal-dependent transcriptional regulator compare
MMP_RS00290 +0.8 2.0 hypothetical protein compare
MMP_RS00950 +0.7 2.9 site-2 protease family protein compare
MMP_RS06685 +0.7 3.7 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08410 +0.7 3.1 DUF169 domain-containing protein compare
MMP_RS00155 +0.7 1.9 heavy metal-binding domain-containing protein compare
MMP_RS08285 +0.7 2.5 serine/threonine protein kinase compare
MMP_RS06860 +0.7 1.2 4Fe-4S binding protein compare
MMP_RS08075 +0.7 3.2 DUF749 domain-containing protein compare
MMP_RS02745 +0.7 1.3 hypothetical protein compare
MMP_RS07775 +0.7 1.6 alanine dehydrogenase compare
MMP_RS00565 +0.7 2.2 CBS domain-containing protein compare
MMP_RS07625 +0.7 1.4 cobalt ECF transporter T component CbiQ compare
MMP_RS08670 +0.7 2.3 metallophosphoesterase compare
MMP_RS03065 +0.7 1.6 AzlC family ABC transporter permease compare
MMP_RS00655 +0.6 1.4 hypothetical protein compare
MMP_RS07765 +0.6 2.5 sodium:alanine symporter family protein compare
MMP_RS06910 +0.6 3.4 RlmF-related methyltransferase compare
MMP_RS05985 +0.6 1.4 hypothetical protein compare
MMP_RS01120 +0.6 2.1 permease compare
MMP_RS02230 +0.6 3.3 sodium-dependent transporter compare
MMP_RS08415 +0.6 1.2 radical SAM protein compare
MMP_RS08455 +0.6 1.6 multiprotein bridging factor aMBF1 compare
MMP_RS08775 +0.6 1.7 methanogenesis marker 9 domain-containing protein compare
MMP_RS08365 +0.6 2.0 energy conserving hydrogenase EhbF compare
MMP_RS02915 +0.6 2.6 amino acid ABC transporter permease compare
MMP_RS00085 +0.6 3.7 DNA cytosine methyltransferase compare
MMP_RS03490 +0.6 1.0 DUF2115 domain-containing protein compare
MMP_RS06345 +0.6 3.0 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS08835 +0.6 2.4 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS00670 +0.6 1.9 TIM barrel protein compare
MMP_RS04145 +0.6 0.9 hypothetical protein compare
MMP_RS03340 +0.6 0.5 ABC transporter ATP-binding protein compare
MMP_RS06650 +0.6 2.4 glycoside hydrolase family 57 protein compare
MMP_RS00700 +0.6 1.6 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS07960 +0.6 2.7 sugar phosphate isomerase/epimerase compare
MMP_RS01320 +0.6 2.1 hypothetical protein compare
MMP_RS01550 +0.6 2.4 DUF1624 domain-containing protein compare
MMP_RS08280 +0.5 1.5 proteasome assembly chaperone family protein compare
MMP_RS03800 +0.5 2.1 hypothetical protein compare
MMP_RS06705 +0.5 1.7 formate/nitrite transporter family protein compare
MMP_RS04775 +0.5 1.0 adenosylhomocysteinase compare
MMP_RS07095 +0.5 0.8 PspC domain-containing protein compare
MMP_RS01060 +0.5 3.0 calcium/sodium antiporter compare
MMP_RS08360 +0.5 1.7 hypothetical protein compare
MMP_RS08390 +0.5 1.6 DUF5400 domain-containing protein compare
MMP_RS08160 +0.5 1.7 EamA family transporter compare
MMP_RS03220 +0.5 1.1 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS08555 +0.5 1.3 hypothetical protein compare
MMP_RS08275 +0.5 2.0 hypothetical protein compare
MMP_RS07560 +0.5 1.9 prefoldin subunit alpha compare
MMP_RS06590 +0.5 1.1 GNAT family N-acetyltransferase compare
MMP_RS07150 +0.5 2.2 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS01260 +0.5 1.9 HDIG domain-containing protein compare
MMP_RS08070 +0.5 1.6 DUF2096 domain-containing protein compare
MMP_RS08700 +0.5 2.1 hypothetical protein compare
MMP_RS06075 +0.5 2.1 class I SAM-dependent methyltransferase compare
MMP_RS01855 +0.5 1.6 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS05470 +0.5 2.1 DUF523 and DUF1722 domain-containing protein compare
MMP_RS08130 +0.5 2.4 IGHMBP2 family helicase compare
MMP_RS00650 +0.5 1.6 ABC transporter ATP-binding protein compare
MMP_RS06320 +0.5 1.5 hypothetical protein compare
MMP_RS07590 +0.5 2.1 hypothetical protein compare
MMP_RS03215 +0.5 2.6 MBL fold metallo-hydrolase compare
MMP_RS00675 +0.5 0.4 nitroreductase family protein compare
MMP_RS06575 +0.5 1.6 fluoride efflux transporter CrcB compare
MMP_RS03675 +0.5 2.7 RimK family alpha-L-glutamate ligase compare
MMP_RS04190 +0.5 2.5 hypothetical protein compare
MMP_RS04405 +0.5 1.5 hypothetical protein compare
MMP_RS06745 +0.5 1.4 DUF2119 domain-containing protein compare
MMP_RS05065 +0.5 1.2 CooT family nickel-binding protein compare
MMP_RS01135 +0.5 2.2 molybdate ABC transporter substrate-binding protein compare
MMP_RS04100 +0.5 1.6 hypothetical protein compare
MMP_RS05715 +0.5 1.5 hypothetical protein compare
MMP_RS04205 +0.5 1.8 carboxymuconolactone decarboxylase family protein compare
MMP_RS00280 +0.5 2.7 DUF2118 domain-containing protein compare
MMP_RS08345 +0.5 2.3 4Fe-4S binding protein compare
MMP_RS05365 +0.5 1.0 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS06500 +0.4 2.2 ATP-binding protein compare
MMP_RS01160 +0.4 1.5 DMT family transporter compare
MMP_RS03430 +0.4 2.1 bile acid:sodium symporter family protein compare
MMP_RS06570 +0.4 1.1 DUF190 domain-containing protein compare
MMP_RS08340 +0.4 1.2 4Fe-4S binding protein compare
MMP_RS08380 +0.4 1.0 phosphatase PAP2 family protein compare
MMP_RS03540 +0.4 1.4 DUF2178 domain-containing protein compare
MMP_RS08475 +0.4 2.2 ABC transporter permease compare
MMP_RS07895 +0.4 0.8 cytochrome c compare
MMP_RS00385 +0.4 2.1 P-II family nitrogen regulator compare
MMP_RS08770 +0.4 1.1 hypothetical protein compare
MMP_RS07100 +0.4 1.8 hypothetical protein compare
MMP_RS07800 +0.4 1.5 ATP-binding cassette domain-containing protein compare
MMP_RS01090 +0.4 1.8 ABC transporter substrate-binding protein compare
MMP_RS01200 +0.4 1.3 hypothetical protein compare
MMP_RS09065 +0.4 2.3 hypothetical protein compare
MMP_RS01985 +0.4 1.3 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06150 +0.4 2.4 hypothetical protein compare
MMP_RS06325 +0.4 0.5 hypothetical protein compare
MMP_RS00645 +0.4 1.6 iron ABC transporter permease compare
MMP_RS06515 +0.4 0.9 UPF0489 family protein compare
MMP_RS01415 +0.4 0.9 DUF2067 domain-containing protein compare
MMP_RS04305 +0.4 0.9 hypothetical protein compare
MMP_RS02790 +0.4 0.4 class III signal peptide-containing protein compare
MMP_RS08485 +0.4 1.8 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS05720 +0.4 1.0 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS08370 +0.4 0.3 cation:proton antiporter subunit C compare
MMP_RS07985 +0.4 2.0 nitroreductase family protein compare
MMP_RS07550 +0.4 2.1 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha compare
MMP_RS01570 +0.4 0.5 hypothetical protein compare
MMP_RS03480 +0.4 1.8 SulP family inorganic anion transporter compare
MMP_RS03900 +0.4 1.5 minichromosome maintenance protein MCM compare
MMP_RS02805 +0.4 0.4 HEPN domain-containing protein compare
MMP_RS00635 +0.4 1.2 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS01850 +0.4 2.2 phosphate ABC transporter substrate-binding protein compare
MMP_RS04060 +0.4 1.0 hypothetical protein compare
MMP_RS07620 +0.4 1.2 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS05315 +0.4 0.6 hypothetical protein compare
MMP_RS01675 +0.4 0.5 hypothetical protein compare
MMP_RS00545 +0.4 0.8 XRE family transcriptional regulator compare
MMP_RS05090 +0.4 1.5 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS00080 +0.4 0.7 RecB-family nuclease compare
MMP_RS06335 +0.4 1.1 HAD family hydrolase compare
MMP_RS06530 +0.4 1.1 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS07890 +0.4 0.7 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS08085 +0.4 1.5 hypothetical protein compare
MMP_RS02410 +0.4 0.9 ABC transporter substrate-binding protein compare
MMP_RS01435 +0.4 0.7 DMT family transporter compare
MMP_RS08890 +0.4 2.2 glycosyltransferase family 4 protein compare
MMP_RS00195 +0.4 2.6 DUF4013 domain-containing protein compare
MMP_RS02770 +0.4 1.0 hypothetical protein compare
MMP_RS05155 +0.4 1.4 hypothetical protein compare
MMP_RS00955 +0.4 2.1 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS03575 +0.4 1.7 ECF transporter S component compare
MMP_RS08325 +0.4 1.6 hypothetical protein compare
MMP_RS00400 +0.4 1.3 tributyrin esterase compare
MMP_RS07805 +0.3 1.2 ABC transporter permease compare
MMP_RS01130 +0.3 1.9 flavoprotein compare
MMP_RS02440 +0.3 1.2 hypothetical protein compare
MMP_RS03130 +0.3 1.5 hypothetical protein compare
MMP_RS02895 +0.3 1.8 DHH family phosphoesterase compare
MMP_RS00940 +0.3 1.2 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS02305 +0.3 1.7 DUF378 domain-containing protein compare
MMP_RS04735 +0.3 1.1 tautomerase family protein compare
MMP_RS01065 +0.3 1.5 alpha/beta hydrolase compare
MMP_RS00795 +0.3 1.7 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS05130 +0.3 2.2 DUF2226 domain-containing protein compare
MMP_RS02590 +0.3 1.6 low molecular weight phosphatase family protein compare
MMP_RS04120 +0.3 1.5 hypothetical protein compare
MMP_RS04225 +0.3 0.9 hypothetical protein compare
MMP_RS08245 +0.3 1.0 DUF4013 domain-containing protein compare
MMP_RS00435 +0.3 1.9 CPBP family intramembrane metalloprotease compare
MMP_RS05780 +0.3 1.8 multidrug resistance efflux transporter family protein compare
MMP_RS02300 +0.3 1.1 NAD(P)H-dependent oxidoreductase compare
MMP_RS08445 +0.3 0.7 DUF2099 family protein compare
MMP_RS06520 +0.3 0.8 DUF1786 domain-containing protein compare
MMP_RS09030 +0.3 1.6 hypothetical protein compare
MMP_RS06660 +0.3 1.2 glycosyltransferase family 4 protein compare
MMP_RS01420 +0.3 0.3 hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For nitrogen source L-Valine in Methanococcus maripaludis S2

For nitrogen source L-Valine across organisms