Experiment set10S108 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Proline

200 most important genes:

  gene name fitness t score description  
MMP_RS03960 -7.0 -1.3 hypothetical protein compare
MMP_RS08715 -6.2 -2.3 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06475 -6.1 -5.2 FAD-dependent oxidoreductase compare
MMP_RS04710 -6.0 -2.5 hypothetical protein compare
MMP_RS08860 -5.2 -6.9 MinD/ParA family protein compare
MMP_RS07345 -5.1 -9.9 glycine synthesis protein GlyXL (from data) compare
MMP_RS04440 -5.0 -12.5 nitrogenase iron protein compare
MMP_RS08720 -4.9 -1.8 4Fe-4S binding protein compare
MMP_RS01500 -4.9 -3.4 CBS domain-containing protein compare
MMP_RS04445 -4.9 -10.0 P-II family nitrogen regulator compare
MMP_RS00555 -4.8 -8.2 MFS transporter compare
MMP_RS08650 -4.7 -5.3 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS04460 -4.7 -18.5 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS06285 -4.5 -2.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01175 -4.5 -5.4 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS04455 -4.5 -21.8 nitrogenase subunit alpha compare
MMP_RS03035 -4.5 -4.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04470 -4.5 -18.3 nitrogenase compare
MMP_RS04465 -4.5 -15.5 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS02240 -4.3 -4.4 methanogenesis marker 7 protein compare
MMP_RS04450 -4.3 -15.0 P-II family nitrogen regulator compare
MMP_RS02685 -4.2 -13.4 molybdate ABC transporter substrate-binding protein compare
MMP_RS06400 -4.1 -2.1 4Fe-4S binding protein compare
MMP_RS01005 -4.1 -1.5 riboflavin synthase compare
MMP_RS00040 -4.1 -6.6 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS03450 -4.1 -2.9 glycine synthesis protein GlyXS (from data) compare
MMP_RS02680 -4.1 -8.5 ABC transporter permease compare
MMP_RS01225 -3.9 -6.0 DUF5379 domain-containing protein compare
MMP_RS02670 -3.9 -12.4 ATP-binding cassette domain-containing protein compare
MMP_RS04685 -3.9 -3.9 DUF126 domain-containing protein compare
MMP_RS07185 -3.9 -13.7 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS05500 -3.8 -8.9 2-isopropylmalate synthase compare
MMP_RS02675 -3.8 -4.4 hypothetical protein compare
MMP_RS06630 -3.8 -1.0 UPF0058 family protein compare
MMP_RS02010 -3.7 -12.3 PHP domain-containing protein compare
MMP_RS00455 -3.7 -8.7 orotate phosphoribosyltransferase-like protein compare
MMP_RS02145 -3.7 -11.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS07605 -3.7 -5.0 diadenylate cyclase compare
MMP_RS07390 -3.6 -3.8 cell division protein FtsZ compare
MMP_RS01800 -3.5 -5.0 TIGR00303 family protein compare
MMP_RS08435 -3.5 -2.8 Era-like GTP-binding protein compare
MMP_RS02245 -3.5 -4.9 hypothetical protein compare
MMP_RS07635 -3.5 -9.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03315 -3.4 -2.0 ferrous iron transport protein A compare
MMP_RS01610 -3.3 -3.1 hypothetical protein compare
MMP_RS06625 -3.3 -3.1 DNA primase compare
MMP_RS02730 -3.3 -12.0 ModD protein compare
MMP_RS01700 -3.3 -0.8 dihydroxy-acid dehydratase compare
MMP_RS07365 -3.2 -12.9 2-phosphoglycerate kinase compare
MMP_RS03445 -3.2 -1.3 methanogenesis marker 17 protein compare
MMP_RS03475 -3.2 -0.8 hypothetical protein compare
MMP_RS07525 -3.2 -9.9 4Fe-4S binding protein compare
MMP_RS08165 -3.2 -2.1 phosphoglycerate dehydrogenase compare
MMP_RS00985 -3.1 -6.3 CDC48 family AAA ATPase compare
MMP_RS03640 -3.1 -4.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07555 -3.1 -1.1 monovalent cation/H+ antiporter subunit E compare
MMP_RS07845 -3.1 -3.3 LL-diaminopimelate aminotransferase compare
MMP_RS08440 -3.1 -3.7 cell division protein SepF compare
MMP_RS03580 -3.1 -4.7 signal recognition particle-docking protein FtsY compare
MMP_RS06895 -3.0 -2.3 selenocysteine-specific translation elongation factor compare
MMP_RS01020 -3.0 -1.5 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS08500 -3.0 -5.9 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS03600 -2.9 -2.9 triose-phosphate isomerase compare
MMP_RS04090 -2.9 -3.4 hypothetical protein compare
MMP_RS01325 -2.9 -3.3 dihydroneopterin aldolase family protein compare
MMP_RS04780 -2.9 -4.9 ribonuclease P compare
MMP_RS07355 -2.9 -1.0 transcription factor S compare
MMP_RS00300 -2.9 -0.9 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06315 -2.9 -1.0 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS03700 -2.9 -9.7 sodium:proton antiporter compare
MMP_RS08645 -2.8 -9.9 UPF0179 family protein compare
MMP_RS03025 -2.8 -5.8 molybdenum cofactor guanylyltransferase compare
MMP_RS01755 -2.8 -1.5 DUF2097 domain-containing protein compare
MMP_RS01795 -2.7 -1.8 methanogenesis marker 6 protein compare
MMP_RS04955 -2.7 -6.8 DNA topoisomerase I compare
MMP_RS07445 -2.7 -5.8 helix-turn-helix domain-containing protein compare
MMP_RS08210 -2.7 -2.6 phosphatidylglycerophosphatase A compare
MMP_RS00810 -2.7 -8.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07730 -2.6 -2.0 pyruvate synthase subunit beta compare
MMP_RS06295 -2.6 -7.1 methanogenesis marker 14 protein compare
MMP_RS09020 -2.6 -2.1 hypothetical protein compare
MMP_RS08855 -2.6 -10.9 hypothetical protein compare
MMP_RS06350 -2.6 -5.4 HesA/MoeB/ThiF family protein compare
MMP_RS00750 -2.6 -2.3 fumarate hydratase compare
MMP_RS00685 -2.6 -4.3 2-phospho-L-lactate guanylyltransferase compare
MMP_RS03015 -2.6 -7.0 GTP 3' 8-cyclase MoaA compare
MMP_RS07380 -2.5 -2.3 transcription elongation factor Spt5 compare
MMP_RS06725 -2.5 -11.5 hypothetical protein compare
MMP_RS06355 -2.5 -2.9 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS05930 -2.5 -2.2 3-isopropylmalate dehydratase large subunit compare
MMP_RS04900 -2.5 -16.3 hypothetical protein compare
MMP_RS02340 -2.5 -2.5 DNA-directed RNA polymerase subunit E'' compare
MMP_RS01265 -2.4 -2.1 hypothetical protein compare
MMP_RS01380 -2.4 -4.6 PHP domain-containing protein compare
MMP_RS07435 -2.4 -1.8 GMP synthase subunit A compare
MMP_RS06020 -2.4 -5.5 archaeoflavoprotein AfpA compare
MMP_RS04870 -2.4 -5.7 TIGR02253 family HAD-type hydrolase compare
MMP_RS05550 -2.4 -0.9 cation:proton antiporter compare
MMP_RS00310 -2.4 -7.8 CBS domain-containing protein compare
MMP_RS07695 -2.4 -8.8 DUF3236 domain-containing protein compare
MMP_RS06120 -2.3 -2.8 UPF0147 family protein compare
MMP_RS04585 -2.3 -10.3 AIR synthase related protein compare
MMP_RS00305 -2.3 -1.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS07075 -2.3 -2.8 phosphomannomutase/phosphoglucomutase compare
MMP_RS01830 -2.3 -2.3 tRNA-Val compare
MMP_RS01385 -2.3 -0.8 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS05430 -2.3 -6.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS01440 -2.2 -6.4 NAAT family transporter compare
MMP_RS05250 -2.2 -1.7 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01220 -2.2 -6.4 hypothetical protein compare
MMP_RS08300 -2.2 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS04850 -2.2 -15.0 UPF0254 family protein compare
MMP_RS00730 -2.2 -6.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS00725 -2.2 -7.7 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06395 -2.2 -4.0 ThiF family adenylyltransferase compare
MMP_RS01545 -2.1 -1.2 CBS domain-containing protein compare
MMP_RS06975 -2.1 -2.4 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07200 -2.1 -6.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00735 -2.1 -3.5 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS05425 -2.1 -5.4 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06730 -2.1 -1.8 phosphopantothenate/pantothenate synthetase compare
MMP_RS07600 -2.1 -1.6 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS05265 -2.0 -2.2 2-isopropylmalate synthase compare
MMP_RS06175 -2.0 -7.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS04890 -2.0 -1.2 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS05765 -2.0 -4.1 M42 family metallopeptidase compare
MMP_RS07700 -2.0 -11.7 DUF1188 domain-containing protein compare
MMP_RS01885 -1.9 -7.8 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS05515 -1.9 -6.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS01875 -1.9 -8.3 N-acetyltransferase compare
MMP_RS08745 -1.9 -5.4 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01725 -1.9 -5.2 class I SAM-dependent methyltransferase family protein compare
MMP_RS08330 -1.9 -6.8 NADH-quinone oxidoreductase subunit H compare
MMP_RS02800 -1.9 -6.5 nucleotidyltransferase domain-containing protein compare
MMP_RS01085 -1.9 -2.2 hypothetical protein compare
MMP_RS05540 -1.8 -2.2 hypothetical protein compare
MMP_RS02195 -1.8 -3.6 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS00915 -1.8 -4.0 DUF116 domain-containing protein compare
MMP_RS02355 -1.8 -3.5 30S ribosomal protein S27ae compare
MMP_RS07535 -1.8 -8.2 4Fe-4S binding protein compare
MMP_RS07710 -1.8 -6.6 cell division protein FtsZ compare
MMP_RS04875 -1.8 -4.8 energy-converting hydrogenase B subunit P compare
MMP_RS06925 -1.7 -2.7 ribonuclease VapC4 compare
MMP_RS06855 -1.7 -8.7 hypothetical protein compare
MMP_RS02780 -1.7 -6.6 hypothetical protein compare
MMP_RS01445 -1.7 -5.4 hypothetical protein compare
MMP_RS00315 -1.7 -7.1 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS05925 -1.7 -3.6 small nuclear ribonucleoprotein compare
MMP_RS03435 -1.7 -1.8 ketol-acid reductoisomerase compare
MMP_RS00720 -1.7 -6.8 metal-dependent hydrolase compare
MMP_RS07575 -1.6 -3.1 RNA ligase partner protein compare
MMP_RS08660 -1.6 -6.7 DHH family phosphoesterase compare
MMP_RS07090 -1.6 -6.3 tRNA (adenine-N1)-methyltransferase compare
MMP_RS08785 -1.6 -1.2 RNA-protein complex protein Nop10 compare
MMP_RS05555 -1.6 -1.3 DUF4040 domain-containing protein compare
MMP_RS03485 -1.6 -3.9 TIGR00267 family protein compare
MMP_RS07955 -1.6 -2.7 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS01880 -1.6 -5.0 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS03020 -1.5 -2.8 peptidylprolyl isomerase compare
MMP_RS06110 -1.5 -2.9 ATP-dependent protease LonB compare
MMP_RS08790 -1.5 -1.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS08705 -1.5 -4.6 sulfopyruvate decarboxylase subunit beta compare
MMP_RS07735 -1.5 -0.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05020 -1.5 -5.2 hypothetical protein compare
MMP_RS08155 -1.5 -4.7 hypothetical protein compare
MMP_RS05460 -1.5 -6.7 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS02345 -1.5 -3.4 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06105 -1.5 -6.9 hydrogenase maturation peptidase HycI compare
MMP_RS05845 -1.5 -1.2 tRNA-intron lyase compare
MMP_RS03440 -1.5 -1.2 MoaD/ThiS family protein compare
MMP_RS06230 -1.5 -2.8 helix-turn-helix domain-containing protein compare
MMP_RS00520 -1.4 -1.5 RNA polymerase Rpb4 family protein compare
MMP_RS00035 -1.4 -4.1 DUF2098 family protein compare
MMP_RS08195 -1.4 -6.5 hypothetical protein compare
MMP_RS01155 -1.4 -4.2 XRE family transcriptional regulator compare
MMP_RS01600 -1.4 -2.5 50S ribosomal protein L15e compare
MMP_RS05640 -1.4 -5.0 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS03205 -1.4 -1.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS04790 -1.4 -6.5 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS07860 -1.4 -0.9 hypothetical protein compare
MMP_RS05920 -1.4 -0.5 50S ribosomal protein L37e compare
MMP_RS02165 -1.3 -5.2 tRNA-dihydrouridine synthase compare
MMP_RS01375 -1.3 -8.0 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase compare
MMP_RS07330 -1.3 -9.5 membrane protein compare
MMP_RS03090 -1.3 -5.3 cation:proton antiporter compare
MMP_RS07005 -1.3 -0.5 4Fe-4S binding protein compare
MMP_RS06900 -1.3 -2.6 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS08635 -1.3 -1.6 UbiA family prenyltransferase compare
MMP_RS06885 -1.3 -2.3 50S ribosome-binding GTPase compare
MMP_RS06340 -1.2 -6.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS08095 -1.2 -4.4 dethiobiotin synthase compare
MMP_RS05295 -1.2 -7.7 minichromosome maintenance protein MCM compare
MMP_RS03420 -1.2 -2.4 acetolactate synthase small subunit compare
MMP_RS05815 -1.2 -1.9 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08570 -1.2 -6.9 coenzyme F420-0:L-glutamate ligase compare
MMP_RS03755 -1.2 -6.8 MarR family transcriptional regulator compare
MMP_RS00060 -1.2 -1.5 3-dehydroquinate synthase II compare
MMP_RS03535 -1.2 -2.4 helix-turn-helix transcriptional regulator compare
MMP_RS05580 -1.1 -7.6 glycosyltransferase compare
MMP_RS05440 -1.1 -4.9 winged helix-turn-helix transcriptional regulator compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nitrogen source experiments

For nitrogen source L-Proline across organisms