Experiment set10S108 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Proline

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS06715 +2.0 12.3 cache domain-containing protein compare
MMP_RS06720 +1.9 10.3 response regulator transcription factor compare
MMP_RS02885 +1.9 12.7 molybdopterin biosynthesis protein compare
MMP_RS07765 +1.8 7.2 sodium:alanine symporter family protein compare
MMP_RS08320 +1.5 5.4 molybdopterin molybdotransferase MoeA compare
MMP_RS08725 +1.4 1.1 Ni/Fe hydrogenase subunit alpha compare
MMP_RS00430 +1.3 2.7 hypothetical protein compare
MMP_RS05835 +1.2 1.4 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS08310 +1.2 2.5 TMEM165/GDT1 family protein compare
MMP_RS04885 +1.2 7.0 sulfite exporter TauE/SafE family protein compare
MMP_RS02290 +1.1 7.0 MBL fold metallo-hydrolase compare
MMP_RS07815 +1.1 1.5 DUF2120 domain-containing protein compare
MMP_RS00185 +1.1 7.3 potassium channel protein compare
MMP_RS00325 +1.0 1.6 RNA-binding protein compare
MMP_RS02045 +1.0 1.6 tRNA-Met compare
MMP_RS02390 +0.9 4.1 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS02605 +0.9 0.8 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS08760 +0.9 3.0 hypothetical protein compare
MMP_RS05975 +0.9 1.4 hypothetical protein compare
MMP_RS00295 +0.9 2.0 gamma carbonic anhydrase family protein compare
MMP_RS08445 +0.9 3.4 DUF2099 family protein compare
MMP_RS00395 +0.9 1.4 MGMT family protein compare
MMP_RS00290 +0.8 3.7 hypothetical protein compare
MMP_RS06545 +0.8 2.2 ferredoxin family protein compare
MMP_RS06685 +0.8 4.7 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06325 +0.8 1.2 hypothetical protein compare
MMP_RS08835 +0.8 3.8 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS05695 +0.8 3.3 phospholipase D-like domain-containing protein compare
MMP_RS00650 +0.8 3.2 ABC transporter ATP-binding protein compare
MMP_RS01320 +0.8 3.0 hypothetical protein compare
MMP_RS00655 +0.7 2.2 hypothetical protein compare
MMP_RS03220 +0.7 1.4 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS03340 +0.7 0.8 ABC transporter ATP-binding protein compare
MMP_RS08235 +0.7 3.2 hypothetical protein compare
MMP_RS08260 +0.7 2.4 DUF99 family protein compare
MMP_RS07645 +0.7 2.4 aldehyde dehydrogenase family protein compare
MMP_RS00660 +0.7 4.6 alkaline phosphatase family protein compare
MMP_RS08415 +0.7 1.5 radical SAM protein compare
MMP_RS06860 +0.7 1.3 4Fe-4S binding protein compare
MMP_RS08160 +0.7 2.3 EamA family transporter compare
MMP_RS08275 +0.7 3.0 hypothetical protein compare
MMP_RS08075 +0.7 2.4 DUF749 domain-containing protein compare
MMP_RS06345 +0.7 3.8 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS05130 +0.7 5.0 DUF2226 domain-containing protein compare
MMP_RS06590 +0.7 2.1 GNAT family N-acetyltransferase compare
MMP_RS06585 +0.7 1.2 DMT family protein compare
MMP_RS02745 +0.7 1.7 hypothetical protein compare
MMP_RS07625 +0.7 1.5 cobalt ECF transporter T component CbiQ compare
MMP_RS01135 +0.7 3.7 molybdate ABC transporter substrate-binding protein compare
MMP_RS03065 +0.7 1.5 AzlC family ABC transporter permease compare
MMP_RS05365 +0.7 1.6 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS05110 +0.7 2.3 16S ribosomal RNA methyltransferase A compare
MMP_RS08430 +0.6 1.8 HAD family hydrolase compare
MMP_RS08395 +0.6 2.3 DsrE family protein compare
MMP_RS06540 +0.6 1.4 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS05720 +0.6 1.5 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS06910 +0.6 3.1 RlmF-related methyltransferase compare
MMP_RS07095 +0.6 1.7 PspC domain-containing protein compare
MMP_RS08285 +0.6 2.8 serine/threonine protein kinase compare
MMP_RS08830 +0.6 1.6 GTP-binding protein compare
MMP_RS01940 +0.6 1.3 MoxR family ATPase compare
MMP_RS02370 +0.6 1.7 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS07915 +0.6 2.5 DUF4870 domain-containing protein compare
MMP_RS01495 +0.6 3.0 TraB/GumN family protein compare
MMP_RS00345 +0.6 1.9 DUF2666 domain-containing protein compare
MMP_RS03300 +0.6 0.5 TOBE domain-containing protein compare
MMP_RS01100 +0.6 0.8 ABC transporter ATP-binding protein compare
MMP_RS07840 +0.6 1.6 ribonuclease III compare
MMP_RS00855 +0.6 3.0 DUF367 family protein compare
MMP_RS02805 +0.6 0.8 HEPN domain-containing protein compare
MMP_RS08775 +0.6 2.4 methanogenesis marker 9 domain-containing protein compare
MMP_RS06745 +0.6 1.9 DUF2119 domain-containing protein compare
MMP_RS06075 +0.6 2.5 class I SAM-dependent methyltransferase compare
MMP_RS00675 +0.6 0.6 nitroreductase family protein compare
MMP_RS00085 +0.6 3.5 DNA cytosine methyltransferase compare
MMP_RS03490 +0.5 1.0 DUF2115 domain-containing protein compare
MMP_RS03150 +0.5 3.1 phosphoglycerate mutase compare
MMP_RS06440 +0.5 3.0 CBS domain-containing protein compare
MMP_RS01570 +0.5 0.8 hypothetical protein compare
MMP_RS08890 +0.5 3.3 glycosyltransferase family 4 protein compare
MMP_RS08130 +0.5 2.9 IGHMBP2 family helicase compare
MMP_RS01200 +0.5 2.0 hypothetical protein compare
MMP_RS01055 +0.5 1.4 hypothetical protein compare
MMP_RS08990 +0.5 2.0 hypothetical protein compare
MMP_RS07590 +0.5 2.9 hypothetical protein compare
MMP_RS05090 +0.5 1.9 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS08280 +0.5 1.4 proteasome assembly chaperone family protein compare
MMP_RS09065 +0.5 3.2 hypothetical protein compare
MMP_RS00990 +0.5 0.9 hypothetical protein compare
MMP_RS06705 +0.5 1.8 formate/nitrite transporter family protein compare
MMP_RS00950 +0.5 2.1 site-2 protease family protein compare
MMP_RS08090 +0.5 2.2 hypothetical protein compare
MMP_RS00155 +0.5 1.4 heavy metal-binding domain-containing protein compare
MMP_RS07195 +0.5 2.0 M20 family metallo-hydrolase compare
MMP_RS03740 +0.5 1.1 indolepyruvate oxidoreductase subunit beta compare
MMP_RS08410 +0.5 1.8 DUF169 domain-containing protein compare
MMP_RS06320 +0.5 2.0 hypothetical protein compare
MMP_RS08555 +0.5 1.4 hypothetical protein compare
MMP_RS02740 +0.5 1.1 hypothetical protein compare
MMP_RS04050 +0.5 1.2 hypothetical protein compare
MMP_RS00700 +0.5 1.9 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS08640 +0.5 2.3 TIM barrel protein compare
MMP_RS00955 +0.5 3.2 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS05435 +0.5 1.9 5'/3'-nucleotidase SurE compare
MMP_RS01855 +0.5 2.1 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS01550 +0.5 2.0 DUF1624 domain-containing protein compare
MMP_RS06660 +0.5 2.4 glycosyltransferase family 4 protein compare
MMP_RS09030 +0.4 2.0 hypothetical protein compare
MMP_RS03540 +0.4 1.5 DUF2178 domain-containing protein compare
MMP_RS04060 +0.4 1.5 hypothetical protein compare
MMP_RS00975 +0.4 2.9 HD domain-containing protein compare
MMP_RS05470 +0.4 2.2 DUF523 and DUF1722 domain-containing protein compare
MMP_RS01095 +0.4 1.2 iron ABC transporter permease compare
MMP_RS08360 +0.4 1.3 hypothetical protein compare
MMP_RS06185 +0.4 2.0 thermonuclease family protein compare
MMP_RS00390 +0.4 1.9 ammonium transporter compare
MMP_RS07985 +0.4 2.7 nitroreductase family protein compare
MMP_RS02405 +0.4 1.3 hypothetical protein compare
MMP_RS05970 +0.4 1.8 class II SORL domain-containing protein compare
MMP_RS04190 +0.4 2.0 hypothetical protein compare
MMP_RS05235 +0.4 1.8 exodeoxyribonuclease III compare
MMP_RS07650 +0.4 2.2 TldD/PmbA family protein compare
MMP_RS08390 +0.4 1.2 DUF5400 domain-containing protein compare
MMP_RS05065 +0.4 0.9 CooT family nickel-binding protein compare
MMP_RS04635 +0.4 1.8 GNAT family N-acetyltransferase compare
MMP_RS02965 +0.4 1.7 carboxymuconolactone decarboxylase family protein compare
MMP_RS01415 +0.4 1.4 DUF2067 domain-containing protein compare
MMP_RS06065 +0.4 2.8 iron ABC transporter substrate-binding protein compare
MMP_RS01685 +0.4 1.0 indolepyruvate oxidoreductase subunit beta compare
MMP_RS01060 +0.4 2.6 calcium/sodium antiporter compare
MMP_RS08380 +0.4 1.5 phosphatase PAP2 family protein compare
MMP_RS03145 +0.4 1.2 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS06305 +0.4 2.0 transporter substrate-binding domain-containing protein compare
MMP_RS02440 +0.4 2.0 hypothetical protein compare
MMP_RS05675 +0.4 0.9 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS00195 +0.4 3.1 DUF4013 domain-containing protein compare
MMP_RS05290 +0.4 1.3 TetR/AcrR family transcriptional regulator compare
MMP_RS04530 +0.4 1.9 ABC transporter permease compare
MMP_RS02790 +0.4 0.4 class III signal peptide-containing protein compare
MMP_RS08685 +0.4 2.0 hypothetical protein compare
MMP_RS00960 +0.4 0.7 iron export ABC transporter permease subunit FetB compare
MMP_RS06190 +0.4 1.1 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS00825 +0.4 1.2 fumarylacetoacetate hydrolase family protein compare
MMP_RS04800 +0.4 1.5 chemotaxis protein CheW compare
MMP_RS03085 +0.4 1.8 endonuclease III compare
MMP_RS00080 +0.4 1.5 RecB-family nuclease compare
MMP_RS08475 +0.4 1.6 ABC transporter permease compare
MMP_RS06055 +0.4 1.7 peroxiredoxin compare
MMP_RS03575 +0.4 1.8 ECF transporter S component compare
MMP_RS08480 +0.4 1.9 molybdate ABC transporter substrate-binding protein compare
MMP_RS08490 +0.4 2.5 hypothetical protein compare
MMP_RS05490 +0.3 0.9 IMPACT family protein compare
MMP_RS01675 +0.3 0.5 hypothetical protein compare
MMP_RS01260 +0.3 1.2 HDIG domain-containing protein compare
MMP_RS07770 +0.3 1.5 alanine racemase compare
MMP_RS01160 +0.3 1.5 DMT family transporter compare
MMP_RS05780 +0.3 1.6 multidrug resistance efflux transporter family protein compare
MMP_RS07800 +0.3 1.5 ATP-binding cassette domain-containing protein compare
MMP_RS08085 +0.3 2.0 hypothetical protein compare
MMP_RS01635 +0.3 1.5 thiamine pyrophosphate-dependent enzyme compare
MMP_RS05525 +0.3 1.4 calcium/sodium antiporter compare
MMP_RS07100 +0.3 1.7 hypothetical protein compare
MMP_RS06650 +0.3 1.4 glycoside hydrolase family 57 protein compare
MMP_RS01065 +0.3 2.0 alpha/beta hydrolase compare
MMP_RS04320 +0.3 2.0 uroporphyrinogen decarboxylase family protein compare
MMP_RS07925 +0.3 1.4 haloacid dehalogenase compare
MMP_RS06375 +0.3 1.1 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS00545 +0.3 1.2 XRE family transcriptional regulator compare
MMP_RS04735 +0.3 1.7 tautomerase family protein compare
MMP_RS08630 +0.3 1.6 archaellar assembly protein FlaJ compare
MMP_RS02825 +0.3 1.7 mechanosensitive ion channel family protein compare
MMP_RS08240 +0.3 1.4 methanogenesis marker 16 metalloprotein compare
MMP_RS04145 +0.3 0.6 hypothetical protein compare
MMP_RS08470 +0.3 1.5 ATP-binding cassette domain-containing protein compare
MMP_RS06905 +0.3 0.7 hypothetical protein compare
MMP_RS04120 +0.3 1.5 hypothetical protein compare
MMP_RS08700 +0.3 1.5 hypothetical protein compare
MMP_RS02375 +0.3 1.7 hypothetical protein compare
MMP_RS05155 +0.3 1.3 hypothetical protein compare
MMP_RS00565 +0.3 1.2 CBS domain-containing protein compare
MMP_RS06680 +0.3 1.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS05980 +0.3 1.6 ferritin compare
MMP_RS04945 +0.3 1.4 hypothetical protein compare
MMP_RS01120 +0.3 1.0 permease compare
MMP_RS02765 +0.3 0.8 ABC transporter ATP-binding protein compare
MMP_RS02985 +0.3 0.4 hypothetical protein compare
MMP_RS07125 +0.3 0.8 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01785 +0.3 1.1 hypothetical protein compare
MMP_RS08205 +0.3 1.4 stage II sporulation protein M compare
MMP_RS05795 +0.3 0.9 redox-regulated ATPase YchF compare
MMP_RS06770 +0.3 1.0 DHH family phosphoesterase compare
MMP_RS06250 +0.3 1.2 hypothetical protein compare
MMP_RS00450 +0.3 0.4 4Fe-4S binding protein compare
MMP_RS02915 +0.3 0.8 amino acid ABC transporter permease compare
MMP_RS06570 +0.3 0.7 DUF190 domain-containing protein compare
MMP_RS07560 +0.3 0.6 prefoldin subunit alpha compare
MMP_RS09060 +0.3 1.9 hypothetical protein compare
MMP_RS01420 +0.3 0.5 hypothetical protein compare
MMP_RS02100 +0.3 0.9 metallophosphoesterase compare
MMP_RS07550 +0.3 1.4 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nitrogen source experiments

For nitrogen source L-Proline across organisms