Experiment set10S103 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Threonine

200 most important genes:

  gene name fitness t score description  
MMP_RS02675 -3.3 -2.6 hypothetical protein compare
MMP_RS03445 -3.2 -0.8 methanogenesis marker 17 protein compare
MMP_RS08370 -3.2 -0.6 cation:proton antiporter subunit C compare
MMP_RS03960 -3.1 -1.3 hypothetical protein compare
MMP_RS02240 -2.9 -2.9 methanogenesis marker 7 protein compare
MMP_RS07345 -2.9 -7.4 glycine synthesis protein GlyXL (from data) compare
MMP_RS01385 -2.8 -0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS04440 -2.7 -8.9 nitrogenase iron protein compare
MMP_RS04445 -2.7 -6.8 P-II family nitrogen regulator compare
MMP_RS03475 -2.7 -0.5 hypothetical protein compare
MMP_RS02145 -2.6 -10.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS02800 -2.6 -8.0 nucleotidyltransferase domain-containing protein compare
MMP_RS01500 -2.6 -2.2 CBS domain-containing protein compare
MMP_RS08460 -2.6 -1.5 proteasome-activating nucleotidase compare
MMP_RS07635 -2.5 -7.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03015 -2.5 -7.9 GTP 3' 8-cyclase MoaA compare
MMP_RS04455 -2.5 -14.4 nitrogenase subunit alpha compare
MMP_RS04460 -2.5 -14.7 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS01980 -2.5 -10.6 trimeric intracellular cation channel family protein compare
MMP_RS07005 -2.4 -0.4 4Fe-4S binding protein compare
MMP_RS02245 -2.4 -2.7 hypothetical protein compare
MMP_RS01725 -2.4 -3.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS05550 -2.4 -0.6 cation:proton antiporter compare
MMP_RS02730 -2.3 -7.9 ModD protein compare
MMP_RS08715 -2.3 -1.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS04465 -2.3 -12.3 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS06625 -2.3 -1.9 DNA primase compare
MMP_RS02670 -2.3 -8.7 ATP-binding cassette domain-containing protein compare
MMP_RS00730 -2.3 -4.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS02280 -2.3 -0.7 DUF211 domain-containing protein compare
MMP_RS08165 -2.3 -1.8 phosphoglycerate dehydrogenase compare
MMP_RS01020 -2.3 -0.9 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05925 -2.3 -2.7 small nuclear ribonucleoprotein compare
MMP_RS04470 -2.2 -11.7 nitrogenase compare
MMP_RS08100 -2.2 -4.3 8-amino-7-oxononanoate synthase compare
MMP_RS04450 -2.2 -9.4 P-II family nitrogen regulator compare
MMP_RS01610 -2.2 -2.6 hypothetical protein compare
MMP_RS02680 -2.2 -4.8 ABC transporter permease compare
MMP_RS02685 -2.2 -10.2 molybdate ABC transporter substrate-binding protein compare
MMP_RS06630 -2.2 -0.5 UPF0058 family protein compare
MMP_RS07355 -2.2 -0.6 transcription factor S compare
MMP_RS08095 -2.1 -6.3 dethiobiotin synthase compare
MMP_RS06485 -2.1 -0.6 zinc ribbon domain-containing protein compare
MMP_RS06370 -2.1 -3.5 biotin synthase BioB compare
MMP_RS00455 -2.1 -8.5 orotate phosphoribosyltransferase-like protein compare
MMP_RS00130 -2.1 -0.9 nickel-responsive transcriptional regulator NikR compare
MMP_RS05515 -2.1 -5.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS02010 -2.0 -8.4 PHP domain-containing protein compare
MMP_RS06400 -2.0 -1.3 4Fe-4S binding protein compare
MMP_RS05765 -2.0 -4.8 M42 family metallopeptidase compare
MMP_RS07365 -2.0 -8.4 2-phosphoglycerate kinase compare
MMP_RS05460 -2.0 -6.8 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS03025 -2.0 -4.8 molybdenum cofactor guanylyltransferase compare
MMP_RS07645 -2.0 -4.2 aldehyde dehydrogenase family protein compare
MMP_RS05280 -2.0 -8.0 COG1361 S-layer family protein compare
MMP_RS03580 -2.0 -2.4 signal recognition particle-docking protein FtsY compare
MMP_RS03450 -2.0 -1.4 glycine synthesis protein GlyXS (from data) compare
MMP_RS00555 -1.9 -5.4 MFS transporter compare
MMP_RS00725 -1.9 -5.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS07525 -1.9 -6.8 4Fe-4S binding protein compare
MMP_RS08720 -1.9 -0.9 4Fe-4S binding protein compare
MMP_RS04500 -1.9 -9.2 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS04215 -1.8 -6.6 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS03485 -1.8 -4.4 TIGR00267 family protein compare
MMP_RS00735 -1.8 -2.1 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS04955 -1.8 -5.2 DNA topoisomerase I compare
MMP_RS02235 -1.8 -8.5 CBS domain-containing protein compare
MMP_RS01265 -1.8 -2.5 hypothetical protein compare
MMP_RS03035 -1.8 -2.7 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04685 -1.8 -1.9 DUF126 domain-containing protein compare
MMP_RS04710 -1.8 -1.4 hypothetical protein compare
MMP_RS06900 -1.8 -2.1 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01455 -1.8 -4.0 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS00040 -1.8 -5.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS08500 -1.8 -4.0 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS06375 -1.7 -5.2 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS01175 -1.7 -3.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08350 -1.7 -0.7 hypothetical protein compare
MMP_RS06980 -1.7 -5.5 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS01830 -1.7 -1.2 tRNA-Val compare
MMP_RS08195 -1.7 -5.2 hypothetical protein compare
MMP_RS06350 -1.7 -4.7 HesA/MoeB/ThiF family protein compare
MMP_RS07555 -1.7 -0.6 monovalent cation/H+ antiporter subunit E compare
MMP_RS08230 -1.6 -5.7 50S ribosomal protein L11 methyltransferase compare
MMP_RS07695 -1.6 -5.5 DUF3236 domain-containing protein compare
MMP_RS07075 -1.6 -3.0 phosphomannomutase/phosphoglucomutase compare
MMP_RS05430 -1.6 -5.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS00915 -1.6 -4.2 DUF116 domain-containing protein compare
MMP_RS01155 -1.6 -4.1 XRE family transcriptional regulator compare
MMP_RS07090 -1.6 -6.9 tRNA (adenine-N1)-methyltransferase compare
MMP_RS08745 -1.6 -4.1 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS03600 -1.6 -1.5 triose-phosphate isomerase compare
MMP_RS06355 -1.6 -1.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03110 -1.6 -3.7 glycosyltransferase family 2 protein compare
MMP_RS00900 -1.6 -1.5 50S ribosomal protein L39e compare
MMP_RS04850 -1.6 -10.6 UPF0254 family protein compare
MMP_RS06270 -1.6 -3.5 TIGR00300 family protein compare
MMP_RS07605 -1.5 -2.7 diadenylate cyclase compare
MMP_RS08660 -1.5 -5.3 DHH family phosphoesterase compare
MMP_RS03385 -1.5 -0.8 cation diffusion facilitator family transporter compare
MMP_RS08210 -1.5 -1.4 phosphatidylglycerophosphatase A compare
MMP_RS05500 -1.5 -5.5 2-isopropylmalate synthase compare
MMP_RS00125 -1.5 -1.0 DUF2798 domain-containing protein compare
MMP_RS01195 -1.5 -0.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS00985 -1.5 -3.0 CDC48 family AAA ATPase compare
MMP_RS03700 -1.5 -5.6 sodium:proton antiporter compare
MMP_RS04900 -1.5 -9.6 hypothetical protein compare
MMP_RS01545 -1.5 -0.7 CBS domain-containing protein compare
MMP_RS02355 -1.4 -1.7 30S ribosomal protein S27ae compare
MMP_RS05285 -1.4 -2.3 MMPL family transporter compare
MMP_RS04585 -1.4 -7.0 AIR synthase related protein compare
MMP_RS01335 -1.4 -1.4 prefoldin subunit beta compare
MMP_RS06285 -1.4 -1.3 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS05635 -1.4 -5.5 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS06725 -1.4 -7.0 hypothetical protein compare
MMP_RS09020 -1.4 -0.9 hypothetical protein compare
MMP_RS07180 -1.4 -4.9 DEAD/DEAH box helicase compare
MMP_RS08645 -1.4 -4.5 UPF0179 family protein compare
MMP_RS00675 -1.4 -0.7 nitroreductase family protein compare
MMP_RS01370 -1.4 -6.1 acetate--CoA ligase family protein compare
MMP_RS03910 -1.3 -1.6 hypothetical protein compare
MMP_RS00315 -1.3 -3.0 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS07845 -1.3 -1.3 LL-diaminopimelate aminotransferase compare
MMP_RS03120 -1.3 -1.8 hypothetical protein compare
MMP_RS01665 -1.3 -2.0 DUF2111 domain-containing protein compare
MMP_RS01795 -1.3 -0.8 methanogenesis marker 6 protein compare
MMP_RS07445 -1.3 -2.7 helix-turn-helix domain-containing protein compare
MMP_RS08570 -1.3 -6.3 coenzyme F420-0:L-glutamate ligase compare
MMP_RS00310 -1.3 -4.8 CBS domain-containing protein compare
MMP_RS03640 -1.3 -2.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01365 -1.3 -1.2 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS06915 -1.3 -3.1 metallophosphoesterase compare
MMP_RS06970 -1.3 -4.6 ribosomal protein S18-alanine N-acetyltransferase compare
MMP_RS05510 -1.2 -3.3 Rrf2 family transcriptional regulator compare
MMP_RS04605 -1.2 -2.6 cobalt ECF transporter T component CbiQ compare
MMP_RS01085 -1.2 -1.2 hypothetical protein compare
MMP_RS00810 -1.2 -3.6 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07700 -1.2 -6.2 DUF1188 domain-containing protein compare
MMP_RS08860 -1.2 -2.5 MinD/ParA family protein compare
MMP_RS05250 -1.2 -0.8 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01220 -1.2 -3.2 hypothetical protein compare
MMP_RS01880 -1.2 -3.9 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS00895 -1.2 -2.1 hypothetical protein compare
MMP_RS06885 -1.2 -1.6 50S ribosome-binding GTPase compare
MMP_RS08240 -1.2 -3.5 methanogenesis marker 16 metalloprotein compare
MMP_RS06120 -1.2 -1.1 UPF0147 family protein compare
MMP_RS01570 -1.2 -0.8 hypothetical protein compare
MMP_RS04615 -1.2 -1.9 PDGLE domain-containing protein compare
MMP_RS05555 -1.2 -0.7 DUF4040 domain-containing protein compare
MMP_RS08105 -1.2 -1.9 6-carboxyhexanoate--CoA ligase compare
MMP_RS06020 -1.1 -2.3 archaeoflavoprotein AfpA compare
MMP_RS07535 -1.1 -4.5 4Fe-4S binding protein compare
MMP_RS07685 -1.1 -3.3 TIGR01212 family radical SAM protein compare
MMP_RS06670 -1.1 -3.5 glucose-6-phosphate isomerase compare
MMP_RS01800 -1.1 -1.8 TIGR00303 family protein compare
MMP_RS06475 -1.1 -2.1 FAD-dependent oxidoreductase compare
MMP_RS07195 -1.1 -2.5 M20 family metallo-hydrolase compare
MMP_RS02930 -1.1 -1.5 class I SAM-dependent methyltransferase compare
MMP_RS02780 -1.1 -4.8 hypothetical protein compare
MMP_RS00110 -1.1 -1.4 hypothetical protein compare
MMP_RS07530 -1.1 -5.8 4Fe-4S binding protein compare
MMP_RS06035 -1.1 -5.5 glycosyltransferase family 2 protein compare
MMP_RS02905 -1.1 -2.6 2-thiouracil desulfurase family protein compare
MMP_RS00685 -1.1 -1.7 2-phospho-L-lactate guanylyltransferase compare
MMP_RS05440 -1.1 -4.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS06295 -1.1 -3.2 methanogenesis marker 14 protein compare
MMP_RS07330 -1.1 -7.8 membrane protein compare
MMP_RS04780 -1.1 -1.4 ribonuclease P compare
MMP_RS02345 -1.0 -1.6 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03495 -1.0 -4.1 Na/Pi cotransporter family protein compare
MMP_RS06315 -1.0 -0.4 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS07335 -1.0 -3.5 tRNA (cytidine(56)-2'-O)-methyltransferase compare
MMP_RS08330 -1.0 -2.6 NADH-quinone oxidoreductase subunit H compare
MMP_RS05965 -1.0 -1.6 carboxymuconolactone decarboxylase family protein compare
MMP_RS05545 -1.0 -3.4 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS01075 -1.0 -1.2 hypothetical protein compare
MMP_RS00520 -1.0 -1.1 RNA polymerase Rpb4 family protein compare
MMP_RS05540 -1.0 -1.6 hypothetical protein compare
MMP_RS03315 -1.0 -0.6 ferrous iron transport protein A compare
MMP_RS07415 -1.0 -2.9 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS02955 -1.0 -1.9 DJ-1/PfpI family protein compare
MMP_RS09010 -1.0 -3.5 hypothetical protein compare
MMP_RS08650 -1.0 -1.6 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS03520 -1.0 -1.2 YwbE family protein compare
MMP_RS07380 -0.9 -0.8 transcription elongation factor Spt5 compare
MMP_RS01875 -0.9 -4.8 N-acetyltransferase compare
MMP_RS02110 -0.9 -1.1 hypothetical protein compare
MMP_RS00620 -0.9 -3.7 4Fe-4S binding protein compare
MMP_RS07390 -0.9 -1.4 cell division protein FtsZ compare
MMP_RS01310 -0.9 -5.2 hypothetical protein compare
MMP_RS05700 -0.9 -2.7 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS03300 -0.9 -0.4 TOBE domain-containing protein compare
MMP_RS05425 -0.9 -1.7 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS04875 -0.9 -1.9 energy-converting hydrogenase B subunit P compare
MMP_RS04620 -0.9 -4.2 cobalt transporter CbiM compare
MMP_RS01470 -0.9 -2.1 ATP-binding cassette domain-containing protein compare
MMP_RS02985 -0.9 -1.6 hypothetical protein compare
MMP_RS01305 -0.9 -6.2 hypothetical protein compare
MMP_RS03225 -0.9 -2.3 acetolactate decarboxylase compare
MMP_RS06385 -0.8 -2.6 hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source L-Threonine in Methanococcus maripaludis S2

For nitrogen source L-Threonine across organisms