| Pathway | #Steps | #Present | #Specific |
|---|
| bis(guanylyl molybdenum cofactor) biosynthesis | 2 | 2 | 2 |
| cadaverine biosynthesis | 1 | 1 | 1 |
| taurine degradation I | 1 | 1 | 1 |
| bis(guanylyl tungstenpterin) cofactor biosynthesis | 1 | 1 | 1 |
| formate oxidation to CO2 | 1 | 1 | 1 |
| guanylyl molybdenum cofactor biosynthesis | 1 | 1 | 1 |
| arginine dependent acid resistance | 1 | 1 | 1 |
| purine deoxyribonucleosides degradation I | 4 | 3 | 3 |
| uracil degradation I (reductive) | 3 | 3 | 2 |
| thymine degradation | 3 | 3 | 2 |
| hypotaurine degradation | 3 | 3 | 2 |
| L-methionine degradation II | 3 | 3 | 2 |
| purine ribonucleosides degradation | 6 | 5 | 4 |
| purine deoxyribonucleosides degradation II | 3 | 2 | 2 |
| superpathway of putrescine biosynthesis | 4 | 4 | 2 |
| putrescine biosynthesis I | 2 | 2 | 1 |
| putrescine degradation V | 2 | 2 | 1 |
| xanthine and xanthosine salvage | 2 | 2 | 1 |
| guanine and guanosine salvage I | 2 | 2 | 1 |
| putrescine biosynthesis III | 2 | 2 | 1 |
| adenine and adenosine salvage I | 2 | 2 | 1 |
| L-arginine degradation III (arginine decarboxylase/agmatinase pathway) | 2 | 2 | 1 |
| L-threonine degradation I | 6 | 5 | 3 |
| adenine and adenosine salvage III | 4 | 3 | 2 |
| β-alanine degradation I | 2 | 1 | 1 |
| β-alanine degradation II | 2 | 1 | 1 |
| ethylene glycol degradation | 2 | 1 | 1 |
| L-threonine degradation V | 2 | 1 | 1 |
| 8-amino-7-oxononanoate biosynthesis III | 2 | 1 | 1 |
| arsenite to oxygen electron transfer | 2 | 1 | 1 |
| putrescine degradation I | 2 | 1 | 1 |
| 8-amino-7-oxononanoate biosynthesis II | 2 | 1 | 1 |
| L-isoleucine biosynthesis I (from threonine) | 7 | 7 | 3 |
| superpathway of purine deoxyribonucleosides degradation | 7 | 6 | 3 |
| superpathway of pyrimidine ribonucleosides degradation | 5 | 5 | 2 |
| 8-amino-7-oxononanoate biosynthesis IV | 5 | 4 | 2 |
| superpathway of polyamine biosynthesis I | 8 | 8 | 3 |
| NAD de novo biosynthesis I | 6 | 6 | 2 |
| pyrimidine deoxyribonucleosides degradation | 3 | 3 | 1 |
| aminopropylcadaverine biosynthesis | 3 | 3 | 1 |
| ethanol degradation II | 3 | 3 | 1 |
| ethanol degradation IV | 3 | 3 | 1 |
| NAD de novo biosynthesis IV (anaerobic) | 6 | 5 | 2 |
| NAD de novo biosynthesis III | 6 | 5 | 2 |
| L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) | 3 | 2 | 1 |
| putrescine degradation IV | 3 | 2 | 1 |
| ethanol degradation III | 3 | 2 | 1 |
| putrescine biosynthesis II | 3 | 2 | 1 |
| oleate biosynthesis III (cyanobacteria) | 3 | 2 | 1 |
| pentose phosphate pathway (oxidative branch) I | 3 | 2 | 1 |
| superpathway of guanine and guanosine salvage | 3 | 2 | 1 |
| adenine and adenosine salvage V | 3 | 1 | 1 |
| histamine degradation | 3 | 1 | 1 |
| arsenite to oxygen electron transfer (via azurin) | 3 | 1 | 1 |
| superpathway of glycol metabolism and degradation | 7 | 4 | 2 |
| purine nucleotides degradation II (aerobic) | 11 | 10 | 3 |
| 8-amino-7-oxononanoate biosynthesis I | 11 | 9 | 3 |
| biotin biosynthesis I | 15 | 13 | 4 |
| NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde | 4 | 4 | 1 |
| biotin biosynthesis from 8-amino-7-oxononanoate I | 4 | 4 | 1 |
| CDP-diacylglycerol biosynthesis I | 4 | 4 | 1 |
| CDP-diacylglycerol biosynthesis II | 4 | 4 | 1 |
| guanosine nucleotides degradation III | 4 | 4 | 1 |
| gondoate biosynthesis (anaerobic) | 4 | 4 | 1 |
| inosine 5'-phosphate degradation | 4 | 4 | 1 |
| octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) | 12 | 9 | 3 |
| superpathway of polyamine biosynthesis II | 8 | 6 | 2 |
| aerobic respiration I (cytochrome c) | 4 | 3 | 1 |
| (2S)-ethylmalonyl-CoA biosynthesis | 4 | 3 | 1 |
| phytol degradation | 4 | 3 | 1 |
| L-valine degradation I | 8 | 5 | 2 |
| superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) | 8 | 4 | 2 |
| aerobic respiration II (cytochrome c) (yeast) | 4 | 2 | 1 |
| L-tryptophan degradation X (mammalian, via tryptamine) | 4 | 2 | 1 |
| D-arabinose degradation II | 4 | 2 | 1 |
| glycolate and glyoxylate degradation I | 4 | 2 | 1 |
| phospholipid remodeling (phosphatidylethanolamine, yeast) | 4 | 2 | 1 |
| spermidine biosynthesis III | 4 | 2 | 1 |
| fatty acid α-oxidation I (plants) | 4 | 2 | 1 |
| superpathway of ornithine degradation | 8 | 3 | 2 |
| D-glucarate degradation I | 4 | 1 | 1 |
| putrescine degradation III | 4 | 1 | 1 |
| D-galactarate degradation I | 4 | 1 | 1 |
| oxalate degradation VI | 4 | 1 | 1 |
| palmitate biosynthesis III | 29 | 21 | 7 |
| tetradecanoate biosynthesis (mitochondria) | 25 | 17 | 6 |
| superpathway of L-isoleucine biosynthesis I | 13 | 12 | 3 |
| superpathway of L-arginine and L-ornithine degradation | 13 | 7 | 3 |
| palmitate biosynthesis II (type II fatty acid synthase) | 31 | 29 | 7 |
| palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) | 9 | 8 | 2 |
| Entner-Doudoroff pathway I | 9 | 8 | 2 |
| nicotine biosynthesis | 9 | 3 | 2 |
| oleate biosynthesis IV (anaerobic) | 14 | 13 | 3 |
| hypoglycin biosynthesis | 14 | 4 | 3 |
| superpathway of fatty acids biosynthesis (E. coli) | 53 | 49 | 11 |
| L-histidine degradation II | 5 | 5 | 1 |
| superpathway of unsaturated fatty acids biosynthesis (E. coli) | 20 | 18 | 4 |
| adenosine nucleotides degradation II | 5 | 4 | 1 |
| fatty acid elongation -- saturated | 5 | 4 | 1 |
| cis-vaccenate biosynthesis | 5 | 4 | 1 |
| octane oxidation | 5 | 3 | 1 |
| propanoyl-CoA degradation II | 5 | 3 | 1 |
| phosphatidate biosynthesis (yeast) | 5 | 3 | 1 |
| cytosolic NADPH production (yeast) | 5 | 3 | 1 |
| sphingosine and sphingosine-1-phosphate metabolism | 10 | 4 | 2 |
| mitochondrial NADPH production (yeast) | 5 | 2 | 1 |
| nucleoside and nucleotide degradation (archaea) | 10 | 3 | 2 |
| desferrioxamine E biosynthesis | 5 | 1 | 1 |
| oxalate degradation III | 5 | 1 | 1 |
| dopamine degradation | 5 | 1 | 1 |
| bisucaberin biosynthesis | 5 | 1 | 1 |
| superpathway of D-glucarate and D-galactarate degradation | 5 | 1 | 1 |
| desferrioxamine B biosynthesis | 5 | 1 | 1 |
| lupanine biosynthesis | 5 | 1 | 1 |
| superpathway of fatty acid biosynthesis II (plant) | 43 | 38 | 8 |
| superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation | 11 | 5 | 2 |
| superpathway of branched chain amino acid biosynthesis | 17 | 17 | 3 |
| superpathway of arginine and polyamine biosynthesis | 17 | 17 | 3 |
| even iso-branched-chain fatty acid biosynthesis | 34 | 24 | 6 |
| anteiso-branched-chain fatty acid biosynthesis | 34 | 24 | 6 |
| odd iso-branched-chain fatty acid biosynthesis | 34 | 24 | 6 |
| (5Z)-dodecenoate biosynthesis I | 6 | 6 | 1 |
| phosphatidylglycerol biosynthesis II | 6 | 6 | 1 |
| phosphatidylglycerol biosynthesis I | 6 | 6 | 1 |
| superpathway of pyrimidine deoxyribonucleosides degradation | 6 | 6 | 1 |
| superpathway of L-threonine metabolism | 18 | 15 | 3 |
| superpathway of phospholipid biosynthesis III (E. coli) | 12 | 10 | 2 |
| (5Z)-dodecenoate biosynthesis II | 6 | 5 | 1 |
| stearate biosynthesis II (bacteria and plants) | 6 | 5 | 1 |
| biotin biosynthesis II | 6 | 4 | 1 |
| stearate biosynthesis IV | 6 | 4 | 1 |
| superpathway of taurine degradation | 6 | 4 | 1 |
| L-lysine degradation X | 6 | 3 | 1 |
| 3-methyl-branched fatty acid α-oxidation | 6 | 3 | 1 |
| formaldehyde oxidation I | 6 | 3 | 1 |
| dTDP-D-desosamine biosynthesis | 6 | 3 | 1 |
| superpathway of nicotine biosynthesis | 12 | 4 | 2 |
| petroselinate biosynthesis | 6 | 2 | 1 |
| palmitoyl ethanolamide biosynthesis | 6 | 2 | 1 |
| Fe(II) oxidation | 6 | 2 | 1 |
| superpathway of stearidonate biosynthesis (cyanobacteria) | 6 | 2 | 1 |
| nucleoside and nucleotide degradation (halobacteria) | 6 | 2 | 1 |
| fluoroacetate and fluorothreonine biosynthesis | 6 | 1 | 1 |
| alkane oxidation | 6 | 1 | 1 |
| noradrenaline and adrenaline degradation | 13 | 4 | 2 |
| streptorubin B biosynthesis | 34 | 20 | 5 |
| myo-inositol degradation I | 7 | 7 | 1 |
| superpathway of purine nucleotide salvage | 14 | 13 | 2 |
| pyridoxal 5'-phosphate biosynthesis I | 7 | 6 | 1 |
| ureide biosynthesis | 7 | 6 | 1 |
| L-lysine biosynthesis VI | 7 | 6 | 1 |
| crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered) | 14 | 7 | 2 |
| serotonin degradation | 7 | 3 | 1 |
| stigma estolide biosynthesis | 7 | 2 | 1 |
| sulfur oxidation IV (intracellular sulfur) | 7 | 2 | 1 |
| ceramide degradation by α-oxidation | 7 | 2 | 1 |
| lipoprotein posttranslational modification (Gram-negative bacteria) | 7 | 2 | 1 |
| diacylglycerol and triacylglycerol biosynthesis | 7 | 2 | 1 |
| L-lysine degradation I | 7 | 2 | 1 |
| 2,4-dinitrotoluene degradation | 7 | 1 | 1 |
| limonene degradation IV (anaerobic) | 7 | 1 | 1 |
| superpathway of fatty acid biosynthesis I (E. coli) | 16 | 15 | 2 |
| pentose phosphate pathway | 8 | 7 | 1 |
| ceramide and sphingolipid recycling and degradation (yeast) | 16 | 4 | 2 |
| anandamide biosynthesis II | 8 | 2 | 1 |
| 2-allylmalonyl-CoA biosynthesis | 8 | 2 | 1 |
| aromatic biogenic amine degradation (bacteria) | 8 | 1 | 1 |
| aspartate superpathway | 25 | 23 | 3 |
| superpathway of glycolysis and the Entner-Doudoroff pathway | 17 | 14 | 2 |
| superpathway of glucose and xylose degradation | 17 | 14 | 2 |
| L-lysine biosynthesis I | 9 | 9 | 1 |
| sucrose biosynthesis I (from photosynthesis) | 9 | 7 | 1 |
| L-lysine biosynthesis II | 9 | 7 | 1 |
| heterolactic fermentation | 18 | 13 | 2 |
| phenylacetate degradation I (aerobic) | 9 | 6 | 1 |
| NAD de novo biosynthesis II (from tryptophan) | 9 | 6 | 1 |
| Entner-Doudoroff pathway II (non-phosphorylative) | 9 | 4 | 1 |
| nicotinate degradation III | 9 | 1 | 1 |
| myo-, chiro- and scyllo-inositol degradation | 10 | 7 | 1 |
| glycolysis IV | 10 | 7 | 1 |
| peptidoglycan recycling II | 10 | 2 | 1 |
| glycolysis III (from glucose) | 11 | 9 | 1 |
| glycolysis II (from fructose 6-phosphate) | 11 | 9 | 1 |
| glycolysis VI (from fructose) | 11 | 7 | 1 |
| ethylmalonyl-CoA pathway | 11 | 7 | 1 |
| superpathway of phenylethylamine degradation | 11 | 6 | 1 |
| formaldehyde assimilation III (dihydroxyacetone cycle) | 12 | 10 | 1 |
| gluconeogenesis III | 12 | 9 | 1 |
| homolactic fermentation | 12 | 9 | 1 |
| superpathway of pyridoxal 5'-phosphate biosynthesis and salvage | 12 | 7 | 1 |
| superpathway of C1 compounds oxidation to CO2 | 12 | 4 | 1 |
| anandamide biosynthesis I | 12 | 3 | 1 |
| superpathway of sulfide oxidation (phototrophic sulfur bacteria) | 12 | 3 | 1 |
| gluconeogenesis I | 13 | 12 | 1 |
| glycolysis I (from glucose 6-phosphate) | 13 | 10 | 1 |
| superpathway of cardiolipin biosynthesis (bacteria) | 13 | 9 | 1 |
| antimycin biosynthesis | 13 | 2 | 1 |
| superpathway of NAD biosynthesis in eukaryotes | 14 | 8 | 1 |
| peptidoglycan recycling I | 14 | 8 | 1 |
| superpathway of phospholipid biosynthesis II (plants) | 28 | 11 | 2 |
| Bifidobacterium shunt | 15 | 12 | 1 |
| superpathway of L-lysine, L-threonine and L-methionine biosynthesis II | 15 | 12 | 1 |
| purine nucleobases degradation I (anaerobic) | 15 | 5 | 1 |
| salinosporamide A biosynthesis | 15 | 3 | 1 |
| cyclosporin A biosynthesis | 15 | 2 | 1 |
| glycerol degradation to butanol | 16 | 9 | 1 |
| superpathway of hyoscyamine (atropine) and scopolamine biosynthesis | 16 | 4 | 1 |
| arsenic detoxification (mammals) | 17 | 8 | 1 |
| superpathway of L-lysine, L-threonine and L-methionine biosynthesis I | 18 | 16 | 1 |
| superpathway of hexitol degradation (bacteria) | 18 | 11 | 1 |
| superpathway of nicotinate degradation | 18 | 2 | 1 |
| hexitol fermentation to lactate, formate, ethanol and acetate | 19 | 14 | 1 |
| superpathway of anaerobic sucrose degradation | 19 | 14 | 1 |
| superpathway of erythromycin biosynthesis | 19 | 3 | 1 |
| superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle | 22 | 17 | 1 |
| superpathway of N-acetylneuraminate degradation | 22 | 15 | 1 |
| superpathway of megalomicin A biosynthesis | 22 | 4 | 1 |
| purine nucleobases degradation II (anaerobic) | 24 | 15 | 1 |
| superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass | 26 | 20 | 1 |
| superpathway of microbial D-galacturonate and D-glucuronate degradation | 31 | 6 | 1 |
| mycolate biosynthesis | 205 | 21 | 5 |
| superpathway of pentose and pentitol degradation | 42 | 11 | 1 |
| superpathway of L-lysine degradation | 43 | 10 | 1 |
| superpathway of mycolate biosynthesis | 239 | 22 | 5 |