Experiment set10IT088 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

Varel_Bryant_medium_Glucose with Irgasan 0.025 mM

200 most important genes:

  gene name fitness t score description  
BT3918 -5.0 -3.5 pyridoxal phosphate biosynthetic protein pdxJ (NCBI ptt file) compare
BT3164 -4.5 -5.4 quinolinate synthetase A (NCBI ptt file) compare
BT3184 -4.2 -14.0 L-aspartate oxidase (NCBI ptt file) compare
BT2074 -3.7 -6.7 ketol-acid reductoisomerase (NCBI ptt file) compare
BT3733 -3.7 -9.5 arginosuccinate lyase (EC 4.3.2.1) (from data) compare
BT3395 -3.6 -8.4 N-succinylglutamate kinase (EC 2.7.2.-) (from data) compare
BT2837 -3.5 -13.7 2-oxoglutarate synthase subunit korB (NCBI ptt file) compare
BT1860 -3.5 -3.4 3-isopropylmalate dehydratase large subunit (NCBI ptt file) compare
BT3759 -3.4 -9.8 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) compare
BT1857 -3.3 -6.4 3-isopropylmalate dehydrogenase (NCBI ptt file) compare
BT2402 -3.3 -12.1 homoserine phosphotransferase HomK (from data) compare
BT1379 -3.3 -3.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
BT2078 -3.3 -10.3 dihydroxy-acid dehydratase (NCBI ptt file) compare
BT1377 -3.3 -3.1 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) compare
BT1375 -3.3 -11.8 aspartokinase (NCBI ptt file) compare
BT3760 -3.3 -4.4 arginosuccinate synthetase (EC 6.3.4.5) (from data) compare
BT2836 -3.2 -15.5 2-oxoglutarate synthase subunit korA (NCBI ptt file) compare
BT0892 -3.2 -2.1 dihydroorotate dehydrogenase (NCBI ptt file) compare
BT2415 -3.1 -11.3 aspartate aminotransferase (NCBI ptt file) compare
BT0704 -3.1 -2.0 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) compare
BT0531 -3.1 -2.1 anthranilate synthase component II (NCBI ptt file) compare
BT0528 -3.1 -2.1 phosphoribosylanthranilate isomerase (EC 5.3.1.24) (from data) compare
BT1843 -3.0 -4.6 adenylosuccinate synthetase (NCBI ptt file) compare
BT3549 -3.0 -5.4 N-succinylcitrulline desuccinylase (EC 3.5.1.-) (from data) compare
BT3361 -3.0 -5.7 erythronate-4-phosphate dehydrogenase (NCBI ptt file) compare
BT0532 -3.0 -4.5 anthranilate synthase component I (NCBI ptt file) compare
BT2401 -3.0 -8.0 threonine synthase (NCBI ptt file) compare
BT2403 -3.0 -9.1 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) compare
BT1844 -2.9 -2.8 transcriptional regulator, putative iron uptake regulation protein (NCBI ptt file) compare
BT3193 -2.9 -13.6 putative coenzyme A transferase (NCBI ptt file) compare
BT1374 -2.9 -4.0 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) compare
BT1746 -2.9 -2.0 conserved hypothetical protein (NCBI ptt file) compare
BT3933 -2.8 -4.7 prephenate dehydrogenase (EC 1.3.1.13) (from data) compare
BT0202 -2.8 -2.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
BT4328 -2.8 -1.9 conserved hypothetical protein (NCBI ptt file) compare
BT0201 -2.7 -1.9 histidinol dehydrogenase (NCBI ptt file) compare
BT2077 -2.7 -4.1 acetolactate synthase large subunit (NCBI ptt file) compare
BT1858 -2.7 -5.3 (R)-citramalate synthase (EC 2.3.1.182) (from data) compare
BT1859 -2.6 -2.5 3-isopropylmalate dehydratase small subunit (NCBI ptt file) compare
BT3980 -2.6 -1.8 hypothetical protein (NCBI ptt file) compare
BT2932 -2.6 -1.8 transcriptional regulator (NCBI ptt file) compare
BT3758 -2.6 -4.2 N-succinylornithine aminotransferase (EC 2.6.1.81) (from data) compare
BT1607 -2.6 -2.5 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) compare
BT2418 -2.6 -3.4 hypothetical protein (NCBI ptt file) compare
BT3717 -2.6 -3.0 N-succinylornithine carbamoyltransferase (EC 2.1.3.11) (from data) compare
BT0067 -2.5 -2.3 hypothetical protein (NCBI ptt file) compare
BT3253 -2.5 -1.7 phosphoribosylamine--glycine ligase (NCBI ptt file) compare
BT1861 -2.5 -6.5 2-isopropylmalate synthase (EC 2.3.3.13) (from data) compare
BT3718 -2.5 -9.4 gamma-glutamyl phosphate reductase (NCBI ptt file) compare
BT1153 -2.4 -4.0 phosphoserine aminotransferase (NCBI ptt file) compare
BT3757 -2.4 -6.8 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) compare
BT0891 -2.4 -1.6 dihydroorotate dehydrogenase electron transfer subunit (NCBI ptt file) compare
BT1979 -2.4 -2.8 Meso-diaminopimelate D-dehydrogenase (NCBI ptt file) compare
BT0200 -2.4 -2.8 ATP phosphoribosyltransferase (NCBI ptt file) compare
BT3761 -2.4 -4.6 N-succinylglutamate synthase (from data) compare
BT0738 -2.3 -2.2 serine hydroxymethyltransferase (NCBI ptt file) compare
BT1270 -2.3 -2.7 putative Na+/H+ antiporter (NCBI ptt file) compare
BT3719 -2.3 -4.5 glutamate 5-kinase (EC 2.7.2.11) (from data) compare
BT1970 -2.3 -8.7 glutamate dehydrogenase (NCBI ptt file) compare
BT1336 -2.3 -3.0 putative translation initiation inhibitor (NCBI ptt file) compare
BT2076 -2.2 -6.6 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) (from data) compare
BT3197 -2.2 -1.4 hypothetical protein (NCBI ptt file) compare
BT0249 -2.2 -1.5 5-methyltetrahydrofolate--homocysteine methyltransferase or methionine synthase (NCBI ptt file) compare
BT3320 -2.2 -5.9 dihydrodipicolinate reductase (NCBI ptt file) compare
BT4644 -2.2 -2.5 putative anti-sigma factor (NCBI ptt file) compare
BT4191 -2.2 -8.0 hypothetical protein (NCBI ptt file) compare
BT4649 -2.2 -2.0 hypothetical protein (NCBI ptt file) compare
BT1476 -2.2 -2.9 aspartate aminotransferase (NCBI ptt file) compare
BT2546 -2.1 -7.8 transcriptional regulator (NCBI ptt file) compare
BT0700 -2.1 -3.8 GTP pyrophosphokinase (NCBI ptt file) compare
BT3554 -2.1 -3.8 conserved hypothetical protein (NCBI ptt file) compare
BT0087 -2.1 -3.0 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT1804 -2.1 -2.8 electron transfer flavoprotein beta-subunit (NCBI ptt file) compare
BT0527 -2.1 -3.4 tryptophan synthase alpha chain (NCBI ptt file) compare
BT0530 -2.0 -3.3 anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) compare
BT1733 -2.0 -3.0 putative phosphoribosylformylglycinamidine synthase (NCBI ptt file) compare
BT2155 -2.0 -4.5 hypothetical protein (NCBI ptt file) compare
BT1381 -1.9 -4.3 formyltetrahydrofolate deformylase (NCBI ptt file) compare
BT4211 -1.9 -1.3 putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) compare
BT0529 -1.9 -1.3 indole-3-glycerol phosphate synthase (NCBI ptt file) compare
BT1837 -1.9 -5.8 putative GTP-binding protein, putative GTPase (NCBI ptt file) compare
BT2843 -1.9 -3.8 integrase (NCBI ptt file) compare
BT1701 -1.9 -2.1 hypothetical protein (NCBI ptt file) compare
BT3035 -1.8 -9.6 carboxy-terminal processing protease precursor (NCBI ptt file) compare
BT0637 -1.8 -3.1 conserved hypothetical protein (NCBI ptt file) compare
BT3074 -1.8 -4.6 conserved hypothetical protein (NCBI ptt file) compare
BT0533 -1.8 -2.1 tryptophan synthase beta chain (NCBI ptt file) compare
BT3936 -1.8 -1.2 prephenate and/or arogenate dehydratase (EC 4.2.1.51) (from data) compare
BT1564 -1.8 -1.2 conserved hypothetical protein (NCBI ptt file) compare
BT0545 -1.8 -2.0 nitrogen regulatory protein P-II (NCBI ptt file) compare
BT1806 -1.7 -4.2 acyl-CoA dehydrogenase (NCBI ptt file) compare
BT0771 -1.7 -2.8 1,4-alpha-glucan branching enzyme (isoamylase or pullulanase type II) (NCBI ptt file) compare
BT1588 -1.6 -3.6 conserved hypothetical protein (NCBI ptt file) compare
BT2173 -1.6 -5.9 hypothetical protein (NCBI ptt file) compare
BT3220 -1.6 -7.4 TPR-repeat-containing protein (NCBI ptt file) compare
BT0352 -1.6 -1.1 conserved hypothetical protein (NCBI ptt file) compare
BT0977 -1.6 -2.2 hypothetical protein (NCBI ptt file) compare
BT4551 -1.6 -1.5 putative GTPase, ThdF family (NCBI ptt file) compare
BT4563 -1.6 -1.5 hypothetical protein (NCBI ptt file) compare
BT2142 -1.6 -1.0 conserved hypothetical protein, with a conserved domain (NCBI ptt file) compare
BT0134 -1.6 -2.0 conserved hypothetical protein (NCBI ptt file) compare
BT1071 -1.6 -2.6 hypothetical protein (NCBI ptt file) compare
BT0231 -1.6 -1.4 excisionase (NCBI ptt file) compare
BT4562 -1.6 -1.0 hypothetical protein (NCBI ptt file) compare
BT0616 -1.6 -1.7 conserved hypothetical protein (NCBI ptt file) compare
BT0163 -1.5 -3.8 conserved hypothetical protein (NCBI ptt file) compare
BT1221 -1.5 -3.3 glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) compare
BT0679 -1.5 -1.7 cation efflux system protein czcB (NCBI ptt file) compare
BT3935 -1.5 -2.9 aminotransferase (NCBI ptt file) compare
BT2169 -1.5 -2.8 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT2003 -1.5 -1.5 putative membrane peptidase (NCBI ptt file) compare
BT3224 -1.5 -2.6 putative lysine decarboxylase (NCBI ptt file) compare
BT1944 -1.5 -1.3 putative transposase (NCBI ptt file) compare
BT1380 -1.5 -1.3 imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) compare
BT1749 -1.4 -4.2 glycine betaine-binding protein precursor (NCBI ptt file) compare
BT0203 -1.4 -1.0 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) compare
BT1378 -1.4 -1.9 imidazole glycerol phosphate synthase subunit hisF (NCBI ptt file) compare
BT0912 -1.4 -0.9 DNA-binding protein HU (NCBI ptt file) compare
BT0519 -1.4 -2.5 hypothetical protein (NCBI ptt file) compare
BT4618 -1.4 -2.1 conserved hypothetical protein (NCBI ptt file) compare
BT3979 -1.4 -2.3 putative methyltransferase (NCBI ptt file) compare
BT1152 -1.4 -1.3 D-3-phosphoglycerate dehydrogenase (NCBI ptt file) compare
BT2845 -1.4 -4.9 conserved hypothetical protein (NCBI ptt file) compare
BT4339 -1.4 -1.9 glutamine synthetase (NCBI ptt file) compare
BT2136 -1.4 -3.1 putative purple acid phosphatase (NCBI ptt file) compare
BT0175 -1.4 -1.6 conserved hypothetical protein (NCBI ptt file) compare
BT1117 -1.4 -1.7 conserved hypothetical protein, with a cAMP-binding domain (NCBI ptt file) compare
BT0215 -1.3 -1.8 iron uptake regulatory protein (NCBI ptt file) compare
BT1903 -1.3 -2.8 hypothetical protein (NCBI ptt file) compare
BT1081 -1.3 -1.2 recombination protein recR (NCBI ptt file) compare
BT3999 -1.3 -5.5 membrane-bound lytic murein transglycosylase D presursor (NCBI ptt file) compare
BT2172 -1.3 -7.2 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) compare
BT3073 -1.3 -6.6 putative TIM-barrel enzyme, possible dehydrogenase, contains a highly conserved dihydrouridine synthase domain (NCBI ptt file) compare
BT3191 -1.3 -3.3 hypothetical protein (NCBI ptt file) compare
BT2314 -1.3 -3.5 hypothetical protein (NCBI ptt file) compare
BT0927 -1.3 -0.8 two-component system sensor histidine kinase (NCBI ptt file) compare
BT1055 -1.3 -1.8 pyruvate formate-lyase activating enzyme (NCBI ptt file) compare
BT4018 -1.3 -1.3 hypothetical protein (NCBI ptt file) compare
BT0887 -1.3 -1.4 conserved hypothetical protein (NCBI ptt file) compare
BT2284 -1.3 -1.9 hypothetical protein (NCBI ptt file) compare
BT3376 -1.3 -4.0 nucleotide sugar transaminase (NCBI ptt file) compare
BT0193 -1.3 -1.4 conserved hypothetical protein (NCBI ptt file) compare
BT2027 -1.2 -1.6 N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
BT1309 -1.2 -2.1 hypothetical protein (NCBI ptt file) compare
BT0409 -1.2 -2.4 putative short-chain dehydrogenase (NCBI ptt file) compare
BT0961 -1.2 -2.0 conserved hypothetical protein (NCBI ptt file) compare
BT2749 -1.2 -8.3 putative membrane-associated HD superfamily hydrolase (NCBI ptt file) compare
BT0462 -1.2 -1.9 putative transcriptional regulator (NCBI ptt file) compare
BT3223 -1.2 -1.6 hypothetical protein (NCBI ptt file) compare
BT3392 -1.2 -2.8 nitroreductase (NCBI ptt file) compare
BT2153 -1.2 -1.9 putative Fe-S oxidoreductases (NCBI ptt file) compare
BT3372 -1.2 -4.0 glycosyltransferase (NCBI ptt file) compare
BT1347 -1.2 -3.1 conserved hypothetical protein (NCBI ptt file) compare
BT2148 -1.2 -2.2 glycosyltransferase (NCBI ptt file) compare
BT1718 -1.2 -4.0 putative 2-aminoethylphosphonate pyruvate aminotransferase (NCBI ptt file) compare
BT1524 -1.2 -1.3 hypothetical protein (NCBI ptt file) compare
BT0739 -1.2 -1.7 hypothetical protein (NCBI ptt file) compare
p5482_02 -1.2 -3.7 hypothetical protein (NCBI) compare
BT2841 -1.2 -1.9 pyruvate kinase (NCBI ptt file) compare
BT1576 -1.2 -1.1 conserved hypothetical protein, with a conserved domain (NCBI ptt file) compare
BT1169 -1.2 -1.5 hypothetical protein (NCBI ptt file) compare
BT1252 -1.2 -2.8 hypothetical protein (NCBI ptt file) compare
BT1370 -1.2 -1.8 NAD dependent nucleotide-diphosphate-sugar epimerase (NCBI ptt file) compare
BT1470 -1.2 -1.4 putative two-component system sensor histidine kinase (NCBI ptt file) compare
BT1608 -1.2 -4.2 capsule biosynthesis protein capA (NCBI ptt file) compare
BT0617 -1.2 -1.0 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfB (NCBI ptt file) compare
BT1419 -1.1 -2.0 hypothetical protein (NCBI ptt file) compare
BT0949 -1.1 -1.0 hypothetical protein (NCBI ptt file) compare
BT1451 -1.1 -1.6 hypothetical protein (NCBI ptt file) compare
BT3268 -1.1 -1.6 glucose-inhibited division protein A (NCBI ptt file) compare
BT0213 -1.1 -3.1 hypothetical protein (NCBI ptt file) compare
BT0395 -1.1 -1.7 hypothetical protein (NCBI ptt file) compare
BT0885 -1.1 -1.2 putative cation efflux pump (NCBI ptt file) compare
BT1076 -1.1 -2.9 two-component system response regulator (NCBI ptt file) compare
BT3639 -1.1 -3.8 ThiF family protein, putative dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis (NCBI ptt file) compare
BT3819 -1.1 -2.5 conserved hypothetical protein (NCBI ptt file) compare
BT0848 -1.1 -1.9 hypothetical protein (NCBI ptt file) compare
BT1137 -1.1 -1.0 hypothetical protein (NCBI ptt file) compare
BT4515 -1.1 -3.2 hypothetical protein (NCBI ptt file) compare
BT2358 -1.1 -1.7 hypothetical protein (NCBI ptt file) compare
BT1206 -1.1 -1.7 conserved hypothetical protein (NCBI ptt file) compare
BT1589 -1.1 -1.3 hypothetical protein (NCBI ptt file) compare
BT0061 -1.1 -2.2 putative tyrosine-protein kinase ptk (NCBI ptt file) compare
BT1972 -1.1 -6.5 phosphoenolpyruvate synthase/pyruvate phosphate dikinase (NCBI ptt file) compare
BT1350 -1.1 -3.2 CDP-glucose 4,6-dehydratase (NCBI ptt file) compare
BT2552 -1.1 -3.9 putative butyrate kinase (NCBI ptt file) compare
BT0558 -1.1 -2.5 mannose-1-phosphate guanylyltransferase (NCBI ptt file) compare
BT1753 -1.1 -2.6 putative methylated-DNA methyltransferase (NCBI ptt file) compare
BT3371 -1.0 -2.5 putative glycosyltransferase yibD (NCBI ptt file) compare
BT4322 -1.0 -1.7 conserved hypothetical protein, with a diacylglycerol kinase catalytic domain (NCBI ptt file) compare
BT3981 -1.0 -2.3 hypothetical protein (NCBI ptt file) compare
BT3712 -1.0 -2.2 ribosomal large subunit pseudouridine synthase D (NCBI ptt file) compare
BT3765 -1.0 -3.2 L-rhamnose:H+ symporter (from data) compare
BT1343 -1.0 -2.9 putative capsule biosynthesis protein (NCBI ptt file) compare
BT1199 -1.0 -2.7 putative protease (NCBI ptt file) compare
BT1894 -1.0 -3.3 TPR-repeat-containing proteins (NCBI ptt file) compare
BT0697 -1.0 -1.3 putative phosphatase/phosphohexomutase (NCBI ptt file) compare
BT1729 -1.0 -5.6 peptide chain release factor 3 (RF-3) (NCBI ptt file) compare
BT1145 -1.0 -1.4 glucose-inhibited division protein (NCBI ptt file) compare
BT1444 -1.0 -1.7 conserved hypothetical protein (NCBI ptt file) compare


Specific Phenotypes

For 2 genes in this experiment

For stress Irgasan in Bacteroides thetaiotaomicron VPI-5482

For stress Irgasan across organisms