Experiment set10IT015 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

Varel_Bryant_medium_Glucose with Chlorpromazine hydrochloride 0.1 mM

200 most important genes:

  gene name fitness t score description  
BT2546 -5.1 -4.7 transcriptional regulator (NCBI ptt file) compare
BT3757 -5.0 -4.8 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) compare
BT4002 -4.8 -1.1 ATPase, ParA family (NCBI ptt file) compare
BT3918 -4.7 -3.3 pyridoxal phosphate biosynthetic protein pdxJ (NCBI ptt file) compare
BT3164 -4.7 -5.6 quinolinate synthetase A (NCBI ptt file) compare
BT2841 -4.4 -1.4 pyruvate kinase (NCBI ptt file) compare
BT1421 -4.3 -3.3 hypothetical protein (NCBI ptt file) compare
BT2837 -4.3 -13.9 2-oxoglutarate synthase subunit korB (NCBI ptt file) compare
BT3184 -4.3 -14.8 L-aspartate oxidase (NCBI ptt file) compare
BT3395 -4.2 -9.3 N-succinylglutamate kinase (EC 2.7.2.-) (from data) compare
BT3193 -4.2 -13.0 putative coenzyme A transferase (NCBI ptt file) compare
BT3733 -4.1 -7.3 arginosuccinate lyase (EC 4.3.2.1) (from data) compare
BT1377 -4.0 -2.7 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) compare
BT4018 -4.0 -2.0 hypothetical protein (NCBI ptt file) compare
BT2402 -4.0 -11.1 homoserine phosphotransferase HomK (from data) compare
BT3759 -3.9 -8.8 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) compare
BT1746 -3.9 -1.5 conserved hypothetical protein (NCBI ptt file) compare
BT3761 -3.9 -3.8 N-succinylglutamate synthase (from data) compare
BT2836 -3.9 -13.9 2-oxoglutarate synthase subunit korA (NCBI ptt file) compare
BT3719 -3.8 -3.7 glutamate 5-kinase (EC 2.7.2.11) (from data) compare
BT2062 -3.8 -7.2 6-phosphofructokinase (NCBI ptt file) compare
BT0892 -3.8 -1.5 dihydroorotate dehydrogenase (NCBI ptt file) compare
BT2074 -3.7 -6.6 ketol-acid reductoisomerase (NCBI ptt file) compare
BT1379 -3.7 -3.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
BT1857 -3.7 -7.0 3-isopropylmalate dehydrogenase (NCBI ptt file) compare
BT2078 -3.7 -8.8 dihydroxy-acid dehydratase (NCBI ptt file) compare
BT1860 -3.7 -4.3 3-isopropylmalate dehydratase large subunit (NCBI ptt file) compare
BT3554 -3.6 -3.5 conserved hypothetical protein (NCBI ptt file) compare
BT3760 -3.6 -2.5 arginosuccinate synthetase (EC 6.3.4.5) (from data) compare
BT3320 -3.6 -5.8 dihydrodipicolinate reductase (NCBI ptt file) compare
BT3933 -3.5 -4.8 prephenate dehydrogenase (EC 1.3.1.13) (from data) compare
BT1843 -3.5 -2.4 adenylosuccinate synthetase (NCBI ptt file) compare
BT0531 -3.5 -2.1 anthranilate synthase component II (NCBI ptt file) compare
BT1153 -3.5 -2.4 phosphoserine aminotransferase (NCBI ptt file) compare
BT2415 -3.5 -10.9 aspartate aminotransferase (NCBI ptt file) compare
BT0532 -3.4 -5.1 anthranilate synthase component I (NCBI ptt file) compare
BT1374 -3.4 -3.3 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) compare
BT3981 -3.4 -2.7 hypothetical protein (NCBI ptt file) compare
BT3718 -3.4 -9.8 gamma-glutamyl phosphate reductase (NCBI ptt file) compare
BT2403 -3.3 -8.5 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) compare
BT0530 -3.3 -2.3 anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) compare
BT3549 -3.3 -6.2 N-succinylcitrulline desuccinylase (EC 3.5.1.-) (from data) compare
BT1861 -3.2 -7.2 2-isopropylmalate synthase (EC 2.3.3.13) (from data) compare
BT1375 -3.2 -8.4 aspartokinase (NCBI ptt file) compare
BT4610 -3.2 -1.8 RecA (NCBI ptt file) compare
BT2076 -3.2 -5.3 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) (from data) compare
BT3361 -3.1 -6.3 erythronate-4-phosphate dehydrogenase (NCBI ptt file) compare
BT_2008 -3.1 -1.7 hypothetical protein (RefSeq) compare
BT4382 -3.1 -3.0 hypothetical protein (NCBI ptt file) compare
BT4644 -3.1 -3.0 putative anti-sigma factor (NCBI ptt file) compare
BT3891 -3.1 -1.0 hypothetical protein (NCBI ptt file) compare
BT2170 -3.1 -6.2 hypothetical protein (NCBI ptt file) compare
BT3758 -3.1 -3.4 N-succinylornithine aminotransferase (EC 2.6.1.81) (from data) compare
BT1193 -3.1 -3.6 conserved hypothetical protein (NCBI ptt file) compare
BT1201 -3.0 -2.3 conserved hypothetical protein (NCBI ptt file) compare
BT1270 -3.0 -2.1 putative Na+/H+ antiporter (NCBI ptt file) compare
BT0201 -3.0 -2.9 histidinol dehydrogenase (NCBI ptt file) compare
BT2088 -3.0 -2.1 hypothetical protein (NCBI ptt file) compare
BT1858 -3.0 -5.4 (R)-citramalate synthase (EC 2.3.1.182) (from data) compare
BT1444 -3.0 -2.2 conserved hypothetical protein (NCBI ptt file) compare
BT0891 -3.0 -1.9 dihydroorotate dehydrogenase electron transfer subunit (NCBI ptt file) compare
BT2749 -2.9 -10.3 putative membrane-associated HD superfamily hydrolase (NCBI ptt file) compare
BT0405 -2.9 -1.8 hypothetical protein (NCBI ptt file) compare
BT1608 -2.9 -6.0 capsule biosynthesis protein capA (NCBI ptt file) compare
BT4733 -2.9 -0.9 conserved hypothetical protein (NCBI ptt file) compare
BT0527 -2.9 -2.0 tryptophan synthase alpha chain (NCBI ptt file) compare
BT2401 -2.9 -8.6 threonine synthase (NCBI ptt file) compare
BT0202 -2.8 -3.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
BT3717 -2.8 -3.9 N-succinylornithine carbamoyltransferase (EC 2.1.3.11) (from data) compare
BT2077 -2.8 -5.7 acetolactate synthase large subunit (NCBI ptt file) compare
BT0519 -2.8 -4.6 hypothetical protein (NCBI ptt file) compare
BT1443 -2.8 -3.8 8-amino-7-oxononanoate synthase (NCBI ptt file) compare
BT2153 -2.8 -2.6 putative Fe-S oxidoreductases (NCBI ptt file) compare
BT2418 -2.8 -3.3 hypothetical protein (NCBI ptt file) compare
BT1607 -2.8 -2.7 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) compare
BT1729 -2.8 -10.4 peptide chain release factor 3 (RF-3) (NCBI ptt file) compare
BT4557 -2.8 -3.8 hypothetical protein (NCBI ptt file) compare
BT3266 -2.7 -10.6 excinuclease ABC subunit C (NCBI ptt file) compare
BT1476 -2.7 -2.6 aspartate aminotransferase (NCBI ptt file) compare
BT1859 -2.7 -3.2 3-isopropylmalate dehydratase small subunit (NCBI ptt file) compare
BT1186 -2.7 -1.4 ABC transporter ATP-binding protein (NCBI ptt file) compare
BT0528 -2.7 -3.2 phosphoribosylanthranilate isomerase (EC 5.3.1.24) (from data) compare
BT3999 -2.7 -8.0 membrane-bound lytic murein transglycosylase D presursor (NCBI ptt file) compare
BT0100 -2.7 -3.1 hypothetical protein (NCBI ptt file) compare
BT0200 -2.6 -3.5 ATP phosphoribosyltransferase (NCBI ptt file) compare
BT3253 -2.6 -1.6 phosphoribosylamine--glycine ligase (NCBI ptt file) compare
BT1380 -2.6 -1.4 imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) compare
BT3811 -2.6 -6.1 putative endothelin-converting enzyme (NCBI ptt file) compare
BT2417 -2.6 -1.0 conserved hypothetical protein (NCBI ptt file) compare
BT1979 -2.6 -2.5 Meso-diaminopimelate D-dehydrogenase (NCBI ptt file) compare
BT2845 -2.6 -4.6 conserved hypothetical protein (NCBI ptt file) compare
BT3325 -2.6 -6.2 hypothetical protein (NCBI ptt file) compare
BT2280 -2.6 -2.4 hypothetical protein (NCBI ptt file) compare
BT0738 -2.6 -3.4 serine hydroxymethyltransferase (NCBI ptt file) compare
BT1381 -2.6 -4.2 formyltetrahydrofolate deformylase (NCBI ptt file) compare
BT3883 -2.5 -1.2 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (NCBI ptt file) compare
BT4271 -2.5 -2.4 hypothetical protein (NCBI ptt file) compare
BT0700 -2.5 -5.2 GTP pyrophosphokinase (NCBI ptt file) compare
BT4191 -2.5 -10.4 hypothetical protein (NCBI ptt file) compare
BT0923 -2.5 -1.3 putative periplasmic protein (NCBI ptt file) compare
BT1446 -2.5 -7.0 dethiobiotin synthetase (NCBI ptt file) compare
BT1539 -2.5 -3.1 cytidine deaminase (NCBI ptt file) compare
BT4322 -2.5 -1.6 conserved hypothetical protein, with a diacylglycerol kinase catalytic domain (NCBI ptt file) compare
BT1442 -2.5 -4.9 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (NCBI ptt file) compare
BT2173 -2.5 -6.8 hypothetical protein (NCBI ptt file) compare
BT1293 -2.5 -13.4 alpha-glucan phosphorylase (NCBI ptt file) compare
BT1557 -2.5 -1.3 hypothetical protein (NCBI ptt file) compare
BT2148 -2.4 -1.6 glycosyltransferase (NCBI ptt file) compare
BT1292 -2.4 -6.0 thiol:disulfide interchange protein (NCBI ptt file) compare
BT3979 -2.4 -1.6 putative methyltransferase (NCBI ptt file) compare
BT2742 -2.4 -1.0 integrase, site-specific recombinase (NCBI ptt file) compare
BT3819 -2.4 -2.9 conserved hypothetical protein (NCBI ptt file) compare
BT4386 -2.4 -1.1 hypoxanthine-guanine phosphoribosyltransferase (NCBI ptt file) compare
BT0533 -2.4 -1.6 tryptophan synthase beta chain (NCBI ptt file) compare
BT0592 -2.4 -2.8 conserved hypothetical protein (NCBI ptt file) compare
BT1733 -2.4 -5.9 putative phosphoribosylformylglycinamidine synthase (NCBI ptt file) compare
BT4008 -2.3 -4.3 conserved hypothetical protein (NCBI ptt file) compare
BT1419 -2.3 -2.2 hypothetical protein (NCBI ptt file) compare
BT0313 -2.3 -1.3 flavodoxin (NCBI ptt file) compare
BT0529 -2.3 -1.6 indole-3-glycerol phosphate synthase (NCBI ptt file) compare
BT0241 -2.3 -1.4 hypothetical protein (NCBI ptt file) compare
BT1445 -2.3 -3.1 putative biotin synthesis protein bioC (NCBI ptt file) compare
BT3912 -2.3 -1.6 conserved hypothetical protein (NCBI ptt file) compare
BT1970 -2.3 -9.4 glutamate dehydrogenase (NCBI ptt file) compare
BT1420 -2.3 -3.0 conserved hypothetical protein (NCBI ptt file) compare
BT1739 -2.2 -10.5 excinuclease ABC subunit A (NCBI ptt file) compare
BT4333 -2.2 -7.8 hypothetical protein (NCBI ptt file) compare
BT2283 -2.2 -0.9 hypothetical protein (NCBI ptt file) compare
BT0876 -2.2 -1.6 conserved hypothetical protein (NCBI ptt file) compare
BT1336 -2.2 -4.1 putative translation initiation inhibitor (NCBI ptt file) compare
BT4649 -2.1 -1.3 hypothetical protein (NCBI ptt file) compare
BT2155 -2.1 -3.0 hypothetical protein (NCBI ptt file) compare
BT0922 -2.1 -2.4 hypothetical protein (NCBI ptt file) compare
BT0848 -2.1 -1.8 hypothetical protein (NCBI ptt file) compare
BT1837 -2.1 -5.3 putative GTP-binding protein, putative GTPase (NCBI ptt file) compare
BT0098 -2.1 -1.1 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT4551 -2.1 -1.4 putative GTPase, ThdF family (NCBI ptt file) compare
BT3035 -2.1 -6.1 carboxy-terminal processing protease precursor (NCBI ptt file) compare
BT0739 -2.1 -1.5 hypothetical protein (NCBI ptt file) compare
BT4487 -2.0 -4.6 putative membrane-bound lytic murein transglycosylase (NCBI ptt file) compare
BT1972 -2.0 -7.9 phosphoenolpyruvate synthase/pyruvate phosphate dikinase (NCBI ptt file) compare
BT0089 -2.0 -1.5 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT1867 -2.0 -1.3 hypothetical protein (NCBI ptt file) compare
BT0122 -2.0 -2.9 3-oxoacyl-[acyl-carrier-protein] synthase III (NCBI ptt file) compare
BT4211 -2.0 -2.3 putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) compare
BT3801 -2.0 -1.9 rteB, two-component system response regulator (NCBI ptt file) compare
BT3936 -2.0 -1.2 prephenate and/or arogenate dehydratase (EC 4.2.1.51) (from data) compare
BT4562 -2.0 -1.0 hypothetical protein (NCBI ptt file) compare
BT4416 -1.9 -2.8 Cu2+ homeostasis protein CutC (NCBI ptt file) compare
BT4490 -1.9 -3.3 hypothetical protein (NCBI ptt file) compare
BT1537 -1.9 -3.6 putative NADH dehydrogenase (NCBI ptt file) compare
BT0214 -1.9 -2.7 hypothetical protein (NCBI ptt file) compare
BT3374 -1.9 -6.7 putative carbamoyl-phosphate-synthetase (NCBI ptt file) compare
BT2449 -1.9 -1.5 hypothetical protein (NCBI ptt file) compare
BT3978 -1.9 -3.6 putative cardiolipin synthetase (NCBI ptt file) compare
BT1152 -1.9 -2.2 D-3-phosphoglycerate dehydrogenase (NCBI ptt file) compare
BT1844 -1.9 -3.2 transcriptional regulator, putative iron uptake regulation protein (NCBI ptt file) compare
BT0827 -1.9 -1.4 hypothetical protein (NCBI ptt file) compare
BT2059 -1.9 -1.1 TonB (NCBI ptt file) compare
BT3935 -1.9 -3.0 aminotransferase (NCBI ptt file) compare
BT1348 -1.9 -4.8 CDP-abequose synthase (NCBI ptt file) compare
BT1948 -1.8 -1.3 hypothetical protein (NCBI ptt file) compare
BT1347 -1.8 -4.7 conserved hypothetical protein (NCBI ptt file) compare
BT3117 -1.8 -2.9 putative oxidoreductase (NCBI ptt file) compare
BT0797 -1.8 -2.0 transcriptional regulator, ArsR family (NCBI ptt file) compare
BT3669 -1.8 -3.9 conserved hypothetical protein (NCBI ptt file) compare
BT0372 -1.8 -2.6 aldose 1-epimerase precursor (NCBI ptt file) compare
BT3578 -1.8 -4.4 hypothetical protein (NCBI ptt file) compare
BT0134 -1.8 -1.7 conserved hypothetical protein (NCBI ptt file) compare
BT3371 -1.8 -3.1 putative glycosyltransferase yibD (NCBI ptt file) compare
BT0481 -1.8 -2.2 polysaccharide export outer membrane protein (NCBI ptt file) compare
BT0203 -1.8 -1.2 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) compare
BT1263 -1.8 -1.0 putative protease I (NCBI ptt file) compare
BT3372 -1.8 -4.3 glycosyltransferase (NCBI ptt file) compare
BT3890 -1.8 -4.4 putative exodeoxyribonuclease VII large subunit (NCBI ptt file) compare
BT4720 -1.8 -4.1 putative RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT1068 -1.7 -2.9 hypothetical protein (NCBI ptt file) compare
BT2172 -1.7 -9.3 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) compare
BT2843 -1.7 -2.2 integrase (NCBI ptt file) compare
BT_t17 pseudo-tRNA -1.7 -1.6 tRNA-OTHER (RefSeq) compare
BT4704 -1.7 -4.5 O-succinylbenzoic acid--CoA ligase (NCBI ptt file) compare
BT1356 -1.7 -3.6 putative capsule polysaccharide export protein (NCBI ptt file) compare
BT0842 -1.7 -1.6 hypothetical protein (NCBI ptt file) compare
BT0731 -1.7 -1.6 hypothetical protein (NCBI ptt file) compare
BT0771 -1.7 -4.5 1,4-alpha-glucan branching enzyme (isoamylase or pullulanase type II) (NCBI ptt file) compare
BT0723 -1.7 -0.8 hypothetical protein (NCBI ptt file) compare
BT4219 -1.7 -2.5 hypothetical protein (NCBI ptt file) compare
BT3396 -1.7 -4.2 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT0616 -1.7 -1.4 conserved hypothetical protein (NCBI ptt file) compare
BT0023 -1.7 -4.1 transposase (NCBI ptt file) compare
BT1339 -1.7 -4.7 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase (NCBI ptt file) compare
BT0770 -1.7 -4.6 conserved hypothetical protein (NCBI ptt file) compare
BT0393 -1.7 -1.7 serine acetyltransferase (NCBI ptt file) compare
BT3224 -1.7 -2.6 putative lysine decarboxylase (NCBI ptt file) compare
BT3363 -1.7 -1.0 lipopolysaccharide core biosynthesis protein LpsA (NCBI ptt file) compare
BT0578 -1.7 -4.6 excinuclease ABC subunit A (NCBI ptt file) compare
BT3942 -1.7 -2.4 conserved hypothetical protein (NCBI ptt file) compare
BT3694 -1.7 -0.9 glycosyltransferase (NCBI ptt file) compare
BT1312 -1.7 -2.6 serine protease precursor (NCBI ptt file) compare
BT1262 -1.7 -1.0 putative transcriptional regulator (NCBI ptt file) compare


Specific Phenotypes

For 6 genes in this experiment

For stress Chlorpromazine hydrochloride in Bacteroides thetaiotaomicron VPI-5482

For stress Chlorpromazine hydrochloride across organisms