Experiment set10H22 for Pseudomonas stutzeri RCH2

Compare to:

Sodium D-Lactate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Psest_2260 +1.5 13.9 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_1635 +1.5 14.1 Signal transduction histidine kinase compare
Psest_1840 +1.2 11.2 Undecaprenyl-phosphate glucose phosphotransferase compare
Psest_2232 +1.1 9.3 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_4010 +1.1 2.2 peroxiredoxin, OsmC subfamily compare
Psest_2775 +1.0 3.1 Glycerol-3-phosphate dehydrogenase compare
Psest_0538 +1.0 9.7 Signal transduction histidine kinase compare
Psest_0309 +0.9 1.2 RND family efflux transporter, MFP subunit compare
Psest_1657 +0.9 1.8 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_1733 +0.9 4.3 flagellar biosynthetic protein FliQ compare
Psest_1567 +0.9 3.2 Transcriptional regulator compare
Psest_2756 +0.9 1.9 hypothetical protein compare
Psest_2454 +0.8 2.1 Rhodanese-related sulfurtransferase compare
Psest_1540 +0.8 1.6 biotin-dependent carboxylase uncharacterized domain compare
Psest_1656 +0.8 2.3 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_0487 +0.8 2.9 Uncharacterized protein conserved in bacteria compare
Psest_3816 +0.8 1.4 DNA-directed RNA polymerase, omega subunit compare
Psest_4088 +0.7 2.7 Transcriptional regulators compare
Psest_0716 +0.7 2.0 Protein of unknown function (DUF3094). compare
Psest_3754 +0.7 1.9 Uncharacterized protein involved in response to NO compare
Psest_4078 +0.7 2.3 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_1725 +0.7 5.5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3937 +0.7 1.1 ATP-dependent protease HslVU, ATPase subunit compare
Psest_1731 +0.7 2.0 flagellar biosynthetic protein FliO compare
Psest_1118 +0.7 1.9 Predicted Fe-S-cluster oxidoreductase compare
Psest_3546 +0.7 1.1 Phosphatidylglycerophosphatase A and related proteins compare
Psest_0988 +0.7 1.9 Protein of unknown function (DUF2845). compare
Psest_4405 +0.7 1.1 hypothetical protein compare
Psest_3168 +0.7 1.8 Molybdopterin converting factor, large subunit compare
Psest_2122 +0.7 1.4 Parvulin-like peptidyl-prolyl isomerase compare
Psest_1735 +0.7 3.4 flagellar biosynthetic protein FlhB compare
Psest_1752 +0.6 1.2 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB compare
Psest_1354 +0.6 1.9 Uncharacterized protein conserved in bacteria compare
Psest_1643 +0.6 1.1 hypothetical protein compare
Psest_0956 +0.6 4.4 Transcriptional regulators compare
Psest_1721 +0.6 3.4 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_1999 +0.6 0.9 pseudouridine synthase compare
Psest_2899 +0.6 1.1 hypothetical protein compare
Psest_0708 +0.6 1.0 outer membrane assembly lipoprotein YfiO compare
Psest_3056 +0.6 2.2 hypothetical protein compare
Psest_0349 +0.6 2.8 DNA polymerase III, alpha subunit (gram-positive type) compare
Psest_3415 +0.6 5.2 hypothetical protein compare
Psest_1122 +0.6 5.0 putative adhesin (DUF1302) (from data) compare
Psest_1809 +0.6 4.1 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_1661 +0.6 1.4 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_4051 +0.6 1.6 molybdenum-pterin binding domain compare
Psest_1720 +0.6 4.0 flagellar motor switch protein FliG compare
Psest_2383 +0.6 3.5 Predicted transcriptional regulators compare
Psest_2001 +0.6 1.1 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_1986 +0.6 1.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_1740 +0.6 3.8 RNA polymerase sigma factor, FliA/WhiG family compare
Psest_1655 +0.6 2.6 NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit compare
Psest_2594 +0.6 1.4 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_3745 +0.5 1.9 Uncharacterized enzyme of heme biosynthesis compare
Psest_0061 +0.5 2.4 hypothetical protein compare
Psest_3554 +0.5 1.3 Uncharacterized protein conserved in bacteria compare
Psest_3449 +0.5 0.8 DJ-1 family protein compare
Psest_3803 +0.5 1.1 DNA repair protein radc compare
Psest_1923 +0.5 2.2 adhesin-associated BNR repeat protein (from data) compare
Psest_1179 +0.5 1.4 2-hydroxy-3-oxopropionate reductase compare
Psest_4064 +0.5 1.6 Lactate dehydrogenase and related dehydrogenases compare
Psest_4315 +0.5 1.7 ABC-type metal ion transport system, permease component compare
Psest_2885 +0.5 1.4 Acyl carrier protein compare
Psest_1660 +0.5 1.0 NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit compare
Psest_4128 +0.5 1.3 Universal stress protein UspA and related nucleotide-binding proteins compare
Psest_4201 +0.5 0.9 general secretion pathway protein F compare
Psest_1315 +0.5 1.3 hypothetical protein compare
Psest_2762 +0.5 2.8 hypothetical protein compare
Psest_2520 +0.5 1.0 Predicted SAM-dependent methyltransferase compare
Psest_1805 +0.5 1.3 integration host factor, beta subunit compare
Psest_1729 +0.5 3.2 flagellar motor switch protein FliM compare
Psest_1734 +0.5 2.3 flagellar biosynthetic protein FliR compare
Psest_1719 +0.5 3.2 flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) compare
Psest_0511 +0.5 0.5 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_0311 +0.5 2.2 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_1065 +0.5 1.1 hypothetical protein compare
Psest_0799 +0.5 1.8 Uncharacterized protein involved in response to NO compare
Psest_2965 +0.5 4.3 fagellar hook-basal body proteins compare
Psest_1994 +0.5 1.7 Amidases related to nicotinamidase compare
Psest_1924 +0.5 4.0 adhesin-associated MmpL efflux pump (from data) compare
Psest_3222 +0.5 1.5 Putative threonine efflux protein compare
Psest_2906 +0.5 1.5 tRNA_Thr_CGT compare
Psest_0993 +0.5 3.1 Glucose-6-phosphate isomerase compare
Psest_3536 +0.4 1.0 hypothetical protein compare
Psest_4142 +0.4 0.7 hypothetical protein compare
Psest_0872 +0.4 0.8 Helix-turn-helix. compare
Psest_1910 +0.4 1.7 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase compare
Psest_3080 +0.4 1.1 AraC-type DNA-binding domain-containing proteins compare
Psest_1718 +0.4 1.6 flagellar hook-basal body complex protein FliE compare
Psest_1901 +0.4 2.1 hypothetical protein compare
Psest_4247 +0.4 1.6 Serine/threonine protein phosphatase compare
Psest_2961 +0.4 1.7 Flagellar basal-body P-ring protein compare
Psest_4103 +0.4 0.7 AraC-type DNA-binding domain-containing proteins compare
Psest_3045 +0.4 0.6 Cold shock proteins compare
Psest_0303 +0.4 2.1 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain compare
Psest_2794 +0.4 1.4 Predicted permease, DMT superfamily compare
Psest_2119 +0.4 2.1 Glycine/D-amino acid oxidases (deaminating) compare
Psest_1313 +0.4 0.6 Uncharacterized conserved small protein compare
Psest_0088 +0.4 2.6 phosphonate metabolism protein PhnP compare
Psest_1722 +0.4 2.9 flagellar protein export ATPase FliI compare
Psest_3371 +0.4 3.0 type IV pilus modification protein PilV compare
Psest_2048 +0.4 1.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_1723 +0.4 2.3 flagellar export protein FliJ compare
Psest_3700 +0.4 0.8 hypothetical protein compare
Psest_2437 +0.4 1.6 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data) compare
Psest_0299 +0.4 1.4 Chemotaxis signal transduction protein compare
Psest_4382 +0.4 3.5 hypothetical protein compare
Psest_2489 +0.4 2.5 branched-chain amino acid uptake carrier compare
Psest_4126 +0.4 1.1 Predicted peroxiredoxins compare
Psest_4252 +0.4 1.1 Uncharacterized protein conserved in bacteria compare
Psest_2066 +0.4 0.7 ABC-type uncharacterized transport system, permease component compare
Psest_1964 +0.4 2.1 hypothetical protein compare
Psest_0908 +0.4 2.2 hypothetical protein compare
Psest_2966 +0.4 2.1 Flagellar hook capping protein compare
Psest_0440 +0.4 1.0 hypothetical protein compare
Psest_2384 +0.4 1.2 Uncharacterized protein conserved in bacteria compare
Psest_3784 +0.4 1.0 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_1872 +0.4 1.4 selT/selW/selH selenoprotein domain compare
Psest_0199 +0.4 2.3 PAS domain S-box compare
Psest_1029 +0.4 1.5 Regulator of competence-specific genes compare
Psest_3365 +0.4 1.5 Predicted membrane protein compare
Psest_1625 +0.4 1.4 hypothetical protein compare
Psest_1134 +0.4 1.1 alkyl hydroperoxide reductase, F subunit compare
Psest_3215 +0.4 1.4 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
Psest_3020 +0.4 2.1 Cell wall-associated hydrolases (invasion-associated proteins) compare
Psest_1612 +0.4 2.2 ABC-type multidrug transport system, ATPase component compare
Psest_3961 +0.4 2.0 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Psest_2971 +0.4 2.5 flagella basal body P-ring formation protein FlgA compare
Psest_2715 +0.4 2.1 ABC-type polysaccharide/polyol phosphate export systems, permease component compare
Psest_0114 +0.4 1.1 RNA polymerase sigma factor, sigma-70 family compare
Psest_1738 +0.4 1.6 flagellar biosynthetic protein FlhF compare
Psest_3753 +0.4 1.9 Acetyltransferases compare
Psest_0692 +0.4 0.7 rRNA methylase, putative, group 3 compare
Psest_0417 +0.4 1.0 Acyl-CoA dehydrogenases compare
Psest_1167 +0.4 0.6 hypothetical protein compare
Psest_1417 +0.4 0.7 hypothetical protein compare
Psest_1863 +0.4 1.0 hypothetical protein compare
Psest_2846 +0.4 1.4 monovalent cation/proton antiporter, MnhG/PhaG subunit compare
Psest_4231 +0.4 1.7 Predicted alpha/beta hydrolase compare
Psest_3813 +0.4 1.9 ribonuclease PH compare
Psest_0348 +0.4 1.4 hypothetical protein compare
Psest_4335 +0.4 0.7 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems compare
Psest_2711 +0.3 1.2 PilZ domain. compare
Psest_3370 +0.3 2.4 prepilin-type N-terminal cleavage/methylation domain compare
Psest_4113 +0.3 2.3 hypothetical protein compare
Psest_2268 +0.3 0.9 Alcohol dehydrogenase, class IV compare
Psest_1819 +0.3 3.1 Nucleoside-diphosphate-sugar epimerases compare
Psest_0231 +0.3 1.7 phosphoesterase, MJ0936 family compare
Psest_3426 +0.3 1.3 Uncharacterized protein conserved in bacteria compare
Psest_2723 +0.3 1.6 Uncharacterized conserved protein compare
Psest_2138 +0.3 1.7 RND family efflux transporter, MFP subunit compare
Psest_2458 +0.3 0.7 MoxR-like ATPases compare
Psest_1681 +0.3 1.7 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E compare
Psest_4273 +0.3 2.1 Lysophospholipase compare
Psest_0181 +0.3 1.7 glycine cleavage system T protein compare
Psest_2404 +0.3 1.7 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases compare
Psest_3198 +0.3 2.1 Putative hemolysin compare
Psest_0165 +0.3 0.9 protein-export chaperone SecB compare
Psest_3024 +0.3 1.3 cytochrome d oxidase, subunit II (cydB) compare
Psest_2360 +0.3 1.2 Uncharacterized protein, putative amidase compare
Psest_0192 +0.3 1.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3295 +0.3 0.9 dinuclear metal center protein, YbgI/SA1388 family compare
Psest_2757 +0.3 0.5 hypothetical protein compare
Psest_3270 +0.3 1.2 probable S-adenosylmethionine-dependent methyltransferase, YraL family compare
Psest_0606 +0.3 2.2 Predicted hydrolase (HAD superfamily) compare
Psest_3938 +0.3 1.3 Uncharacterized protein conserved in bacteria compare
Psest_0796 +0.3 1.2 ABC-type transport system involved in multi-copper enzyme maturation, permease component compare
Psest_2405 +0.3 0.7 NAD-dependent protein deacetylases, SIR2 family compare
Psest_2942 +0.3 2.0 Surface lipoprotein compare
Psest_2136 +0.3 2.3 Predicted homoserine dehydrogenase compare
Psest_2487 +0.3 1.3 uncharacterized domain 1 compare
Psest_2293 +0.3 0.6 hypothetical protein compare
Psest_4241 +0.3 1.5 hypothetical protein compare
Psest_3913 +0.3 0.8 hypothetical protein compare
Psest_0257 +0.3 0.6 Predicted Zn-dependent peptidases compare
Psest_4087 +0.3 2.1 hypothetical protein compare
Psest_3373 +0.3 1.9 Tfp pilus assembly protein PilX compare
Psest_2229 +0.3 1.1 Uncharacterized protein conserved in bacteria compare
Psest_3244 +0.3 0.9 Protein of unknown function (DUF2726). compare
Psest_0637 +0.3 1.6 Short-chain dehydrogenases of various substrate specificities compare
Psest_1659 +0.3 1.0 NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit compare
Psest_3100 +0.3 1.2 RNA polymerase sigma factor RpoE compare
Psest_0848 +0.3 1.0 hypothetical protein compare
Psest_2123 +0.3 0.7 fusion of gluconokinase (EC 2.7.1.12) and the small permease component of the D-gluconate TRAP transporter (from data) compare
Psest_1016 +0.3 1.4 putative TIM-barrel protein, nifR3 family compare
Psest_1518 +0.3 0.8 tRNA_Ser_CGA compare
Psest_4221 +0.3 1.0 homoserine kinase, Neisseria type compare
Psest_3250 +0.3 1.2 Rho termination factor, N-terminal domain. compare
Psest_2667 +0.3 1.1 Uncharacterized protein involved in propionate catabolism compare
Psest_1173 +0.3 1.0 hypothetical protein compare
Psest_1837 +0.3 1.9 Endoglucanase compare
Psest_1728 +0.3 1.4 Flagellar basal body-associated protein compare
Psest_1511 +0.3 2.1 Predicted redox protein, regulator of disulfide bond formation compare
Psest_1408 +0.3 1.4 Predicted unusual protein kinase compare
Psest_0584 +0.3 1.4 hypothetical protein compare
Psest_3736 +0.3 0.7 Uncharacterized protein conserved in bacteria compare
Psest_0406 +0.3 2.0 Fatty acid hydroxylase superfamily. compare
Psest_2959 +0.3 2.4 flagellar hook-associated protein FlgK compare
Psest_2773 +0.3 1.8 glycerol kinase compare
Psest_2724 +0.3 0.6 hypothetical protein compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium D-Lactate in Pseudomonas stutzeri RCH2

For carbon source Sodium D-Lactate across organisms