Experiment set10H12 for Pseudomonas stutzeri RCH2

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a-Ketoglutaric acid disodium salt hydrate carbon source

200 most important genes:

  gene name fitness t score description  
Psest_3944 -7.9 -5.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0508 -7.1 -9.7 gamma-glutamyl phosphate reductase compare
Psest_3650 -6.7 -13.7 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0279 -6.7 -7.9 methionine biosynthesis protein MetW compare
Psest_3648 -6.4 -9.7 anthranilate phosphoribosyltransferase compare
Psest_2584 -6.4 -4.4 Phosphoribosylanthranilate isomerase compare
Psest_3721 -6.3 -9.6 Malic enzyme compare
Psest_2591 -6.3 -4.3 3-isopropylmalate dehydratase, large subunit compare
Psest_0155 -6.2 -6.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3647 -6.1 -8.4 Indole-3-glycerol phosphate synthase compare
Psest_0062 -6.1 -14.1 tryptophan synthase, alpha subunit compare
Psest_3866 -6.0 -21.3 threonine ammonia-lyase, biosynthetic, long form compare
Psest_2578 -6.0 -15.1 O-succinylhomoserine sulfhydrylase compare
Psest_2590 -5.9 -1.9 3-isopropylmalate dehydratase, small subunit compare
Psest_3298 -5.9 -14.2 histidinol dehydrogenase compare
Psest_0152 -5.8 -8.5 Imidazoleglycerol-phosphate dehydratase compare
Psest_0063 -5.8 -14.0 tryptophan synthase, beta subunit compare
Psest_3299 -5.7 -14.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_3226 -5.7 -1.8 Predicted membrane protein compare
Psest_0153 -5.6 -16.2 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0085 -5.6 -18.5 alpha-ketoglutarate TRAP transporter, solute receptor component (from data) compare
Psest_3864 -5.5 -18.9 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0326 -5.5 -22.9 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0280 -5.4 -19.8 homoserine O-acetyltransferase compare
Psest_3384 -5.3 -12.3 glutamate 5-kinase compare
Psest_0325 -5.2 -13.0 Putative threonine efflux protein compare
Psest_4131 -5.1 -10.8 alpha-ketoglutarate sensor protein (mifS) (from data) conserved
Psest_3649 -4.8 -14.2 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0687 -4.7 -11.8 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0313 -4.7 -9.0 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_1473 -4.7 -9.5 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_2589 -4.4 -12.0 3-isopropylmalate dehydrogenase compare
Psest_0084 -4.3 -21.2 alpha-ketoglutarate TRAP transporter, 4TM/12TM components (from data) compare
Psest_3943 -4.0 -6.2 Phosphoribosyl-AMP cyclohydrolase compare
Psest_1037 -4.0 -3.7 acetolactate synthase, small subunit compare
Psest_2579 -3.6 -4.9 amidophosphoribosyltransferase compare
Psest_4132 -3.5 -9.8 alpha-ketoglutarate DNA-binding response regulator (mifR) (from data) conserved
Psest_3998 -3.3 -10.8 glutamate--cysteine ligase compare
Psest_0327 -3.2 -6.0 Transcriptional regulator compare
Psest_1295 -3.0 -9.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_1772 -2.9 -6.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3297 -2.9 -13.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_2329 -2.9 -16.8 Transcriptional regulator compare
Psest_0489 -2.8 -2.6 phosphoserine phosphatase SerB compare
Psest_2088 -2.7 -3.5 Uncharacterized protein conserved in bacteria compare
Psest_3818 -2.7 -8.5 endoribonuclease L-PSP, putative compare
Psest_1686 -2.6 -7.5 fatty acid/phospholipid synthesis protein PlsX compare
Psest_2651 -2.6 -6.7 DNA topoisomerase I, bacterial compare
Psest_0442 -2.4 -2.3 ATPases of the AAA+ class compare
Psest_2333 -2.4 -1.8 Protein of unknown function (DUF3359). compare
Psest_3322 -2.3 -18.9 TIGR02099 family protein compare
Psest_1474 -2.3 -1.6 phosphoribosylaminoimidazole synthetase compare
Psest_0498 -2.2 -1.6 ribosome small subunit-dependent GTPase A compare
Psest_0999 -2.1 -3.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3159 -2.0 -7.4 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0718 -1.9 -5.8 nicotinate-nucleotide pyrophosphorylase compare
Psest_4044 -1.9 -3.1 type I site-specific deoxyribonuclease, HsdR family compare
Psest_1013 -1.9 -3.6 phosphoribosylamine--glycine ligase compare
Psest_1496 -1.9 -1.6 Holliday junction DNA helicase, RuvA subunit compare
Psest_1167 -1.8 -1.8 hypothetical protein compare
Psest_4191 -1.7 -4.1 Transcriptional regulator compare
Psest_3988 -1.7 -8.5 phosphoenolpyruvate carboxykinase (ATP) compare
Psest_3351 -1.7 -5.5 peptide chain release factor 3 compare
Psest_3810 -1.6 -1.9 orotate phosphoribosyltransferase compare
Psest_0771 -1.6 -10.5 Acyl-CoA hydrolase compare
Psest_2945 -1.6 -1.6 septum site-determining protein MinC compare
Psest_1947 -1.5 -1.0 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_0284 -1.5 -10.4 pyridoxal phosphate enzyme, YggS family compare
Psest_2810 -1.5 -5.2 5'/3'-nucleotidase SurE compare
Psest_3766 -1.5 -2.8 Uncharacterized protein conserved in bacteria compare
Psest_0138 -1.5 -8.7 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_3228 -1.4 -8.8 Zn-dependent protease with chaperone function compare
Psest_0139 -1.4 -5.0 ABC-type histidine transport system, ATPase component compare
Psest_2719 -1.4 -1.9 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_1486 -1.4 -2.9 hypothetical protein compare
Psest_3168 -1.4 -1.9 Molybdopterin converting factor, large subunit compare
Psest_0136 -1.4 -9.8 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_0277 -1.3 -2.0 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Psest_1724 -1.3 -3.8 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_2122 -1.3 -1.4 Parvulin-like peptidyl-prolyl isomerase compare
Psest_3809 -1.3 -6.4 hypothetical protein compare
Psest_0137 -1.3 -6.8 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_3145 -1.3 -1.9 hypothetical protein compare
Psest_1277 -1.3 -8.4 2-isopropylmalate synthase, yeast type compare
Psest_3927 -1.3 -4.8 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_3301 -1.3 -4.2 Predicted transcriptional regulator, BolA superfamily compare
Psest_0722 -1.3 -6.5 Predicted ATPase compare
Psest_0212 -1.3 -1.6 exodeoxyribonuclease V, gamma subunit compare
Psest_2325 -1.2 -7.4 alpha-L-glutamate ligase-related protein compare
Psest_3288 -1.2 -8.4 type IV-A pilus assembly ATPase PilB compare
Psest_0445 -1.2 -9.0 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_0297 -1.2 -4.7 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2285 -1.2 -3.4 ATP-dependent protease La compare
Psest_1509 -1.2 -6.4 quinolinate synthetase complex, A subunit compare
Psest_0292 -1.2 -2.4 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_1643 -1.2 -1.1 hypothetical protein compare
Psest_2324 -1.2 -9.7 hypothetical protein compare
Psest_2101 -1.2 -1.7 hypothetical protein compare
Psest_2809 -1.2 -2.5 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_2304 -1.1 -1.3 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Psest_2442 -1.1 -2.9 hypothetical protein compare
Psest_3720 -1.1 -8.9 penicillin-binding protein, 1A family compare
Psest_0193 -1.1 -1.2 conserved hypothetical protein compare
Psest_0491 -1.1 -7.6 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_1012 -1.1 -3.6 Signal transduction histidine kinase compare
Psest_4270 -1.0 -6.4 TRAP transporter, DctM subunit conserved
Psest_2323 -1.0 -8.4 Uncharacterized protein conserved in archaea compare
Psest_3146 -1.0 -2.0 hypothetical protein compare
Psest_4269 -1.0 -5.6 C4-dicarboxylate transporter, DctQ subunit (from data) conserved
Psest_2862 -1.0 -5.8 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_2650 -1.0 -2.7 hypothetical protein compare
Psest_2786 -1.0 -1.3 Domain of unknown function (DUF3597). compare
Psest_3185 -1.0 -1.3 MoxR-like ATPases compare
Psest_2756 -1.0 -1.4 hypothetical protein compare
Psest_3123 -1.0 -2.3 dihydroorotase, homodimeric type compare
Psest_3543 -1.0 -2.8 hypothetical protein compare
Psest_1957 -0.9 -6.6 outer membrane porin, OprD family. compare
Psest_3782 -0.9 -5.2 Alcohol dehydrogenase, class IV compare
Psest_1516 -0.9 -2.2 Uncharacterized lipoprotein compare
Psest_3860 -0.9 -2.3 Predicted permeases compare
Psest_0154 -0.9 -2.4 Uncharacterized conserved protein compare
Psest_3129 -0.9 -1.2 tyrosine recombinase XerD compare
Psest_0466 -0.9 -3.2 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_2293 -0.8 -1.2 hypothetical protein compare
Psest_3101 -0.8 -6.5 L-aspartate oxidase compare
Psest_0851 -0.8 -5.8 Transcriptional regulators compare
Psest_4098 -0.8 -2.1 Superfamily I DNA and RNA helicases compare
Psest_4097 -0.8 -5.7 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_3816 -0.8 -1.1 DNA-directed RNA polymerase, omega subunit compare
Psest_3148 -0.8 -1.0 hypothetical protein compare
Psest_3806 -0.8 -3.9 Phosphomannomutase compare
Psest_2946 -0.8 -2.5 septum site-determining protein MinD compare
Psest_3178 -0.8 -2.5 formyltetrahydrofolate deformylase compare
Psest_1656 -0.8 -1.4 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_4220 -0.7 -1.6 Protein of unknown function (DUF2782). compare
Psest_0693 -0.7 -6.5 His Kinase A (phosphoacceptor) domain./PAS fold./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_0511 -0.7 -1.3 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_3862 -0.7 -5.9 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0170 -0.7 -3.1 5,10-methenyltetrahydrofolate synthetase compare
Psest_1506 -0.7 -3.0 queuosine biosynthesis protein QueC compare
Psest_0457 -0.7 -2.4 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_4003 -0.7 -2.3 TIGR00153 family protein compare
Psest_3715 -0.7 -5.6 type IV pilus secretin (or competence protein) PilQ compare
Psest_3413 -0.7 -1.9 hypothetical protein compare
Psest_2334 -0.7 -5.6 Uncharacterized protein conserved in bacteria compare
Psest_0449 -0.7 -4.8 Glutamine synthetase adenylyltransferase compare
Psest_3693 -0.7 -1.7 Glycosyltransferases involved in cell wall biogenesis compare
Psest_0248 -0.7 -3.6 Transcriptional regulator compare
Psest_3882 -0.7 -4.6 Opacity protein and related surface antigens compare
Psest_0300 -0.7 -3.8 Methyl-accepting chemotaxis protein compare
Psest_2025 -0.7 -0.9 cold shock domain protein CspD compare
Psest_1054 -0.7 -3.9 Diaminopimelate decarboxylase compare
Psest_3080 -0.7 -1.3 AraC-type DNA-binding domain-containing proteins compare
Psest_3883 -0.7 -3.2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3287 -0.7 -3.2 Type II secretory pathway, component PulF compare
Psest_0697 -0.7 -1.5 ribosomal protein L9 compare
Psest_2327 -0.7 -3.2 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein compare
Psest_1704 -0.7 -0.9 Dehydrogenases (flavoproteins) compare
Psest_4103 -0.7 -1.0 AraC-type DNA-binding domain-containing proteins compare
Psest_1001 -0.7 -1.7 hypothetical protein compare
Psest_4363 -0.7 -4.1 ATPases involved in chromosome partitioning compare
Psest_0060 -0.7 -1.3 Predicted Fe-S protein compare
Psest_4268 -0.7 -4.7 tripartite ATP-independent periplasmic transporter solute receptor, DctP family compare
Psest_2643 -0.7 -1.6 Beta-glucosidase-related glycosidases compare
Psest_0257 -0.7 -0.9 Predicted Zn-dependent peptidases compare
Psest_1204 -0.7 -1.8 Transcriptional regulators compare
Psest_1695 -0.7 -2.2 Tfp pilus assembly protein PilZ compare
Psest_3212 -0.7 -2.4 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_3535 -0.7 -2.1 hypothetical protein compare
Psest_0952 -0.6 -1.5 Uncharacterized conserved protein compare
Psest_0028 -0.6 -2.5 Coproporphyrinogen III oxidase compare
Psest_3323 -0.6 -2.3 ribonuclease, Rne/Rng family compare
Psest_2605 -0.6 -0.9 transcriptional activator RfaH compare
Psest_1000 -0.6 -4.1 PAS domain S-box compare
Psest_1750 -0.6 -2.3 Protein of unknown function (DUF2802). compare
Psest_2282 -0.6 -2.0 Dihydroorotate dehydrogenase compare
Psest_1082 -0.6 -1.2 Enoyl-CoA hydratase/carnithine racemase compare
Psest_0706 -0.6 -4.1 His Kinase A (phosphoacceptor) domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_2626 -0.6 -1.5 Flp pilus assembly protein CpaB compare
Psest_3180 -0.6 -3.5 Exonuclease I compare
Psest_0415 -0.6 -2.8 dethiobiotin synthase compare
Psest_1354 -0.6 -1.5 Uncharacterized protein conserved in bacteria compare
Psest_1597 -0.6 -2.1 Protein of unknown function (DUF2933). compare
Psest_1919 -0.6 -1.4 Uncharacterized membrane protein (homolog of Drosophila rhomboid) compare
Psest_4158 -0.6 -1.0 Flagellar motor protein compare
Psest_0054 -0.6 -2.7 hypothetical protein compare
Psest_1595 -0.6 -1.0 Copper chaperone compare
Psest_0650 -0.6 -2.4 RNA polymerase sigma factor, sigma-70 family compare
Psest_1249 -0.6 -3.3 serine O-acetyltransferase compare
Psest_1665 -0.6 -2.3 hypothetical protein compare
Psest_4088 -0.6 -1.7 Transcriptional regulators compare
Psest_3954 -0.6 -2.1 Small protein A (tmRNA-binding) compare
Psest_2935 -0.6 -1.6 hypothetical protein compare
Psest_0357 -0.6 -1.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_4405 -0.6 -1.1 hypothetical protein compare
Psest_1305 -0.6 -1.4 Heat shock protein compare
Psest_4067 -0.6 -2.0 Predicted membrane protein compare
Psest_0285 -0.6 -3.5 pilus retraction protein PilT compare
Psest_2967 -0.6 -2.4 flagellar basal-body rod protein FlgC compare
Psest_3361 -0.6 -2.6 Uncharacterized protein conserved in bacteria compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source a-Ketoglutaric acid disodium salt hydrate in Pseudomonas stutzeri RCH2

For carbon source a-Ketoglutaric acid disodium salt hydrate across organisms