Protein Info for Xcc-8004.874.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 794 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF07715: Plug" amino acids 60 to 172 (113 residues), 41.8 bits, see alignment E=1.4e-14 PF00593: TonB_dep_Rec" amino acids 265 to 741 (477 residues), 166.1 bits, see alignment E=2.6e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to xcc:XCC3474)

Predicted SEED Role

"S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284)" in subsystem Glutathione-dependent pathway of formaldehyde detoxification (EC 1.1.1.284)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.284

Use Curated BLAST to search for 1.1.1.284

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X5D2 at UniProt or InterPro

Protein Sequence (794 amino acids)

>Xcc-8004.874.1 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) (Xanthomonas campestris pv. campestris strain 8004)
MAAGKRRAAGVQRKTLAGACAMALLAGPAMGIAAEAPQVTWLDRIEVTATPIPGTTIDAA
QLPYMVQSANRAELSRGRSNNLGDLLQRRFVGVDGNDVQGSAFQNDLTFHGFRASALPGA
SQGVSVYLDGVRFNEPFADIVSWDMLPEAAINAVTLMPGSNPLFGPNTLGGAVVLTTASG
LTAPGAQGELSIGSGARKRLDASYGIAGNDGWHGFVAVTGFDENGWRDASEGRLGTVFGK
VGKQGEQTDWSLSVLHGRSRLIGNGLLPDTSYTDDGSRPGLYRADRRAVYTSPDLTRNRN
TLFTAQLDHRSDADTALHALAYSRVGRRDTVNGDIGEDYEEFVEECASGYAADGTALDAD
CDVARADADTLPTGALNTTQMRQEAQGVAVNVSKQWGAHALSTGATFDRGHVRYQQFARE
GWVQPDRSVAADPDAERAFFSGVRGSTKTLGVFVADTWALDAATHLTAAVRWNHVTVDNI
LSTAEDGDRPRERFVYAKANPSLGLTHRLHEGLTVYGSVAQNSRAPTAIELGCADPTQPC
RLPTGLQADPRLEQIISRTYELGARWAPSQDSDVTLSVYRADNRDDILFLRAPDTQLGYF
DNVGRTRYQGADAAMRFQAGAWQWSAGYSYLDATYRSDGELLSGERVITLRPGLRIAALP
RHNLKLGVEWQGDALTLGAGLRAVSGRVASGNEDGQVDNAEDGEPAPERIDIGTAGYALV
DLQARWQLSERLSLFARIDNVFDRQYATYAAVAEDVFPDGELARPQDAPVETGPARFLAP
GVPRQYLIGVRWAL