Protein Info for Xcc-8004.625.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03331: S-adenosylmethionine decarboxylase proenzyme
  • amino acids 7 to 262 (256 residues), 468.9 bits, E=2e-145
• PF02675: AdoMet_dc
  • amino acids 48 to 170 (123 residues), 53.4 bits, E=1.5e-18

Best Hits

Swiss-Prot: 100% identical to SPED_XANCP: S-adenosylmethionine decarboxylase proenzyme (speD) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K01611, S-adenosylmethionine decarboxylase [EC: 4.1.1.50] (inferred from 98% identity to xom:XOO_3932)

MetaCyc: 64% identical to S-adenosylmethionine decarboxylase proenzyme (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1A" in subsystem Polyamine Metabolism (EC 4.1.1.50)

MetaCyc Pathways

• L-methionine salvage cycle III (9/11 steps found)
• spermidine biosynthesis I (2/2 steps found)
• superpathway of polyamine biosynthesis II (6/8 steps found)
• superpathway of arginine and polyamine biosynthesis (12/17 steps found)
• spermine biosynthesis (1/2 steps found)
• L-methionine salvage cycle I (bacteria and plants) (8/12 steps found)
• spermidine biosynthesis III (2/4 steps found)
• aminopropylcadaverine biosynthesis (1/3 steps found)
• superpathway of polyamine biosynthesis I (4/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Methionine metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.50

Sequence Analysis Tools

See Q4UZF5 at UniProt or InterPro

Protein Sequence (264 amino acids)

>Xcc-8004.625.1 S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1A (Xanthomonas campestris pv. campestris strain 8004)
VVKPLPRLRLQGFNNLTKALSFNIYDVCYARTEEERQRYIEYIDEQYDADRLTQILTDVA
EIIGANILNIARQDYDPQGASVTILISEEPVIDKKQAGKELISDAVVAHMDKSHITVHTY
PETHPQEGIATFRADIDVATCGVISPLKALNYLIESLESDIVIMDYRVRGFTRDVKGKKH
YIDHKINSIQHFLAKNVKSRYEMFDVNVYQENIFHTKMHLKDFDLDQYLFEERAKNLSFK
ERMKIETLLKREIEELFHGRNLSE