Protein Info for Xcc-8004.4909.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Biosynthetic arginine decarboxylase (EC 4.1.1.19)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01273: arginine decarboxylase
  • amino acids 51 to 670 (620 residues), 864.5 bits, E=2.4e-264
• PF02784: Orn_Arg_deC_N
  • amino acids 126 to 386 (261 residues), 134.1 bits, E=8.6e-43
• PF17810: Arg_decarb_HB
  • amino acids 411 to 493 (83 residues), 72 bits, E=6.3e-24
• PF17944: Arg_decarbox_C
  • amino acids 622 to 669 (48 residues), 46.5 bits, 6.5e-16

Best Hits

Swiss-Prot: 100% identical to SPEA_XANCP: Biosynthetic arginine decarboxylase (speA) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K01585, arginine decarboxylase [EC: 4.1.1.19] (inferred from 100% identity to xca:xccb100_4055)

Predicted SEED Role

"Biosynthetic arginine decarboxylase (EC 4.1.1.19)" in subsystem Acid resistance mechanisms or Arginine and Ornithine Degradation or Polyamine Metabolism (EC 4.1.1.19)

MetaCyc Pathways

• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (3/3 steps found)
• putrescine biosynthesis II (3/3 steps found)
• arginine dependent acid resistance (1/1 steps found)
• superpathway of polyamine biosynthesis II (6/8 steps found)
• superpathway of arginine and polyamine biosynthesis (12/17 steps found)
• L-arginine degradation III (arginine decarboxylase/agmatinase pathway) (1/2 steps found)
• putrescine biosynthesis I (1/2 steps found)
• spermidine biosynthesis III (2/4 steps found)
• superpathway of putrescine biosynthesis (2/4 steps found)
• superpathway of polyamine biosynthesis I (4/8 steps found)
• superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (3/11 steps found)
• superpathway of L-arginine and L-ornithine degradation (4/13 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.19

Sequence Analysis Tools

See A0A0H2XBP1 at UniProt or InterPro

Protein Sequence (675 amino acids)

>Xcc-8004.4909.1 Biosynthetic arginine decarboxylase (EC 4.1.1.19) (Xanthomonas campestris pv. campestris strain 8004)
MRLTARSEPSSAPFPSGTGRQIGADCNGPSACQALQFTPFCPSRDNEMSDWSLDQARKTY
SIPHWADGYFDVNDAGHVVVRPTADGPAVSLPEVVDAARAAGAKLPLLVRFPDILGQRLG
KLQAAFAQAQADWDYAGGYTAVYPIKVNQHRGVAGTLASHHGEGFGLEAGSKPELMAVLA
LSRPGGLIVCNGYKDREYIRLALIGRKLGLQTFIVIEKPSELNLVLEEARALDVKPGLGV
RMRLASLGAGKWQNSGGDKAKFGLSPRQVLDLWKSLRDTEYADSLNLLHFHMGSQISNVR
DIANGMREATRYFVELSRLGAKISHVDVGGGLGIDYEGTRSRSYCSINYGLHSYASNIVQ
PLASACEEHGLPPPRIVTECGRAMTAHHAVLIANVSEVEQAPEGRVPDAHDDEPAAIRHL
REIHDELDVRPAVELFQEAQHFHAEGLSAYALGQIDLTHRARIDDLFYAIAHGVRARLSF
DEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAIDQVFPIVPIERLNEAPQRRGIIAD
MTCDSDGMVKTYVENESLDSSLPLHGLNPGESYRIGFFLVGAYQEILGDIHNLFGDTDAV
EVAVDGTGYRIAQQRRGDTTDVMLDYVGYQLDTLRATYAERIAAAQLPPERAQELHDALE
AGLTGYTYLSDEPLG