Protein Info for Xcc-8004.4439.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1347 TIGR01735: phosphoribosylformylglycinamidine synthase" amino acids 3 to 814 (812 residues), 1172.7 bits, see alignment E=0 PF18076: FGAR-AT_N" amino acids 35 to 146 (112 residues), 100.7 bits, see alignment E=1.1e-32 PF18072: FGAR-AT_linker" amino acids 162 to 211 (50 residues), 78 bits, see alignment (E = 1.2e-25) PF02769: AIRS_C" amino acids 420 to 578 (159 residues), 128.2 bits, see alignment E=6.7e-41 amino acids 877 to 1022 (146 residues), 48.7 bits, see alignment E=2e-16 PF13507: GATase_5" amino acids 1095 to 1346 (252 residues), 336.4 bits, see alignment E=1.9e-104

Best Hits

Predicted SEED Role

"Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)" in subsystem De Novo Purine Biosynthesis (EC 6.3.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2XCL1 at UniProt or InterPro

Protein Sequence (1347 amino acids)

>Xcc-8004.4439.1 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) (Xanthomonas campestris pv. campestris strain 8004)
MVLEGASALSPFRRARLETRLQTLVPALRLTGAWHVYFIRADAGRTPDQATLQRILQAEP
APAPRDEAASSRYVVPRLGTLSPWSSKATELMRGAGQPIQRVERGTRIDLAGWPEGEADQ
AAVAKLLHDPMTQSLLGSAAAAEALFNVPDPGQLERIPLDALEQANGDLGLALAQDEIDY
LRERFAALGRDPADVELMMFAQANSEHCRHKIFNASWTIDGKPQERSLFRMIKHTHQQTP
QHTLSAYSDNAAVVEGVPAARFRPDPATGEYRSEAVVPSAFAIKVETHNHPTAIAPFPGA
ATGAGGEIRDEGATGRGGKPKAGLTGFSVSHLRIPTLPQPWEAPRALNPRMAPALDIMLD
GPLGGAAFNNEFGRPNLLGYFRSFELAEGQGLTRAYDKPIMLAGGLGAIDRNQVEKLRLQ
PGDAVIVLGGPAMLIGLGGGAASSVAAGDSAEALDFASVQRENPEMERRCQEVIDHCVAL
GTDNPIRWFHDVGAGGLSNAIPELLHDSGVGGVIDLARVPSDDPSLSPLELWCNESQERY
VLGVPQARLDEFAAICARERCPFAAVGVATAEERLVVGYGVFDAANRESGIGNRNSALPA
AEAASAHSLFPTPDSPLPINLPMDVLFGKAPKMHRDAVHPAAPQWPVLQTGALDLQEAGL
RVLAHPTVASKSFLVTIGDRSVGGLTAREQMIGPWQLPLADCAITLAGFETFDGEAMSIG
ERTPLALLNAAASARMAVGEAITNLCAAPVQTLDSIKLSANWMAAAGHAGEDALLYDAVR
AVGMELCPALELSIPVGKDSLSMQAQWQVGNGESGIGNGETPAPSASAIPDSRLPIPGET
LKSVSPVSLIISAFAPVSDVRTQLTPLLQREDESELWLIGLGGGKQRLGGSVLAQVYADD
SALPAFGGETPDLDDPQRLRQFFELIRDAREGGLLLAYHDRSDGGAFAALCEMAFASRQG
LDITLDAWGDDAFRSLFNEELGAVVQIANEDRAAFADLVERHALTECAQRIARPTGTPRV
RVSGQGRVLAEWRWEALFDAWWSVTHAMQKLRDNPDSADEERAVARNFQAPGLRPKLVFD
PSEDVAAPFVATGARPKVAILREQGVNGQIEMAYNFERAGFRAFDVHMSDLIEGRVDLAQ
FAGFAACGGFSYGDVLGAGRGWATSILERAALRDAFAAFFARSDTFALGVCNGCQMLSQL
KDIIPGAEHWPRFLRNRSEQFEARTALLEVVESPSILLRGMAGSRIPVAVAHGEGRAEFD
TAVDQAAARVALRFIDGDGAVASQYPLNPNGSPDGITGLTSTDGRATILMPHPERTPRSV
NLSWHPAGWGEDSPWLRMFRNARVWCG