Protein Info for Xcc-8004.4105.1 in Xanthomonas campestris pv. campestris strain 8004
Annotation: Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 56% identical to PPIA_HELPY: Peptidyl-prolyl cis-trans isomerase (ppiA) from Helicobacter pylori (strain ATCC 700392 / 26695)
KEGG orthology group: K03768, peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC: 5.2.1.8] (inferred from 98% identity to xom:XOO_0887)Predicted SEED Role
"Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)" in subsystem Queuosine-Archaeosine Biosynthesis (EC 5.2.1.8)
Isozymes
Compare fitness of predicted isozymes for: 5.2.1.8
Use Curated BLAST to search for 5.2.1.8
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0H2XC30 at UniProt or InterPro
Protein Sequence (164 amino acids)
>Xcc-8004.4105.1 Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (Xanthomonas campestris pv. campestris strain 8004) MSLIATFDTSRGPIVVELYPEKAPLTVANFVNLARRGFYNGLSFHRVIADFMIQGGCPEG SGRGGPGYRFEDEANNGVGHERGVLSMANAGPNTNGSQFFITHTATPWLDGKHTVFGKVT QGLDVVDSVAQGDTINTLTIEGDTDAVLAAKADRVAEWNKILAA