Protein Info for Xcc-8004.4065.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Exopolyphosphatase (EC 3.6.1.11)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 TIGR03706: exopolyphosphatase" amino acids 17 to 312 (296 residues), 327.7 bits, see alignment E=3.4e-102 PF02541: Ppx-GppA" amino acids 30 to 313 (284 residues), 224.6 bits, see alignment E=1.8e-70 PF21447: Ppx-GppA_III" amino acids 321 to 490 (170 residues), 150.9 bits, see alignment E=3.4e-48

Best Hits

Swiss-Prot: 40% identical to GPPA_PSEHT: Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (gppA) from Pseudoalteromonas haloplanktis (strain TAC 125)

KEGG orthology group: K01524, exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC: 3.6.1.11 3.6.1.40] (inferred from 100% identity to xca:xccb100_3391)

Predicted SEED Role

"Exopolyphosphatase (EC 3.6.1.11)" in subsystem Phosphate metabolism (EC 3.6.1.11)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.11 or 3.6.1.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2XC02 at UniProt or InterPro

Protein Sequence (508 amino acids)

>Xcc-8004.4065.1 Exopolyphosphatase (EC 3.6.1.11) (Xanthomonas campestris pv. campestris strain 8004)
MPMPSPTIPPLRDGDFLAAIDLGSNSFHMVIARYLMGQLRVVDRLRETVRMADGLDGKGG
ISNEARQRALECLARFGQRIREVPSLRVRALATNTVRQLRSPQAFLMPAETALGHAIEVV
SGREEARLIYLGVAHAQPPKPDQRRLVIDIGGGSTEFIIGRGFQTLERESLQAGCIASTR
RFFPGGKLSKKKWKDALTEIGAEFQQFAGQYKALGWHEAIGSSGTHKAIGEMCAAMKLTK
GAITAEALPALRDELLKAKRIEDIQLPGLAAERRPIIAGGILVLEAAFQALGLEKLMVSK
AAMREGILYDMLGRGGENDPRDSSVASLVQRYGIDEAQAQRVEATACRLFDQVCESWQLD
GDDAQVLRRAARLHELGLMIAHSQYHVHGSYILEHSDIAGFSRQEQQVLAALVRTHRRNV
PKTAFDALPDRLLLPTRRKAALLRLAVLLHRAHETDPIPTLELTADDNRLSLILSQAWID
SRPLLRADLIGEVEGMAGLGIMFRPFVT