Protein Info for Xcc-8004.3295.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Imidazolonepropionase (EC 3.5.2.7)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01224: imidazolonepropionase
  • amino acids 26 to 398 (373 residues), 461.7 bits, E=8.4e-143
• PF01979: Amidohydro_1
  • amino acids 62 to 383 (322 residues), 47.9 bits, E=1.2e-16
• PF07969: Amidohydro_3
  • amino acids 213 to 378 (166 residues), 44.7 bits, E=1.4e-15

Best Hits

Swiss-Prot: 100% identical to HUTI_XANCP: Imidazolonepropionase (hutI) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K01468, imidazolonepropionase [EC: 3.5.2.7] (inferred from 100% identity to xcb:XC_2653)

MetaCyc: 53% identical to imidazolonepropionase (Pseudomonas fluorescens)
Imidazolonepropionase. [EC: 3.5.2.7]

Predicted SEED Role

"Imidazolonepropionase (EC 3.5.2.7)" in subsystem Histidine Degradation (EC 3.5.2.7)

MetaCyc Pathways

• L-histidine degradation II (5/5 steps found)
• L-histidine degradation VI (7/8 steps found)
• L-histidine degradation I (4/4 steps found)
• L-histidine degradation III (4/6 steps found)

KEGG Metabolic Maps

• Histidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.7

Sequence Analysis Tools

See Q4UTC0 at UniProt or InterPro

Protein Sequence (401 amino acids)

>Xcc-8004.3295.1 Imidazolonepropionase (EC 3.5.2.7) (Xanthomonas campestris pv. campestris strain 8004)
MHCDVLWHNARLMTLDAGDGGLGSVDDGVVACQDGTIVYAGPAADAPPLQASHVHDCQRR
WISPGLIDCHTHLVYAGNRANEFEQRLRGASYAQIAAAGGGIVATVRATRAADDAALLAA
SLPRLDALLAEGVTTLEIKSGYGLTLEDEIKQLRVARQLATLRQVEVVPTFLGAHAVPPG
AQGQTYIDAVCQEMIPAVAAQGLAEAVDVFCEHLAFSPAQAEQVFVAARAHGLQIKIHAE
QLSNQHGAALAARYGALSADHIEYLDQAGIDAMANAGTVAVLLPGAFYFTRDTQLPPIPA
LRAAGVPLALATDCNPGTSPLTSPLLAMNMAATLFRMTVDGCITGFTREAARALGRGNRL
GRLRAGMQCDLAIWDIDAPADLVYRMGFNPLHTRVWRGHPC