Protein Info for Xcc-8004.2182.1 in Xanthomonas campestris pv. campestris strain 8004
Annotation: NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form" in subsystem Glutamate dehydrogenases or Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 1.4.1.2)
MetaCyc Pathways
- L-alanine degradation II (to D-lactate) (3/3 steps found)
- L-glutamate degradation I (1/1 steps found)
- ethene biosynthesis IV (engineered) (1/3 steps found)
- L-glutamate degradation V (via hydroxyglutarate) (6/10 steps found)
- L-glutamate degradation XI (reductive Stickland reaction) (3/7 steps found)
- methylaspartate cycle (10/19 steps found)
- 4-aminobutanoate degradation V (1/7 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.4.1.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0H2X6K5 at UniProt or InterPro
Protein Sequence (1669 amino acids)
>Xcc-8004.2182.1 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form (Xanthomonas campestris pv. campestris strain 8004) MTAKKAASNSSTTSAKPVAERAVPVVATAPQAITLEPVFAALRKRYPAARQSEVQLFAAD FYRRMEEDEFPNHPPEQWAALAADMLEFARTRKAGTVNVRVFNPTLKSHGYESPHTLLQI VNDDMPFLVDSVSMTLSELGIGVHVLGHPVLRIARDKGGKLTAVGEGKSESLMVLEIDRQ PADEMPKVEAAIRKVLAEVRAIVHDWAAMREKMVMLADDLATRRLPMDDISRHEAQEFLR WAASDHFTFFGYREYRVEKQDGQEMLAPVEESGLGLMRGHDISPARPVTSLAAHGLNTSA KLKDALILTKTNARSRVHRVGYMDYIGILEFDAKGRIVGEQRFLGLFTSSAYNRRPWEIP LVRQRYEYVMSKSGLTPSSHSGKALRHILEKLPREELFQSNQDELYRTAIGILGLQERVR SRMFLRRDKYSRFISALVYIPRERFNTDVRLRIEALLKDALHGEYIDSSVVLGESPLAQL HLIVRAKSGEALEFDTTALEARLAHVLRNWHDALREALVARHGEAHGLRMAANFGRALPA GYIEDSSIESAVADVEHLAALDGPNDLHLSLQEVRRDSAVRLDTGDGLRLKLYRQLDDIP LSDAMPMMENMGLRVISERPYRLQVSDTPVYIQDFEVESTAGHIDASSADAAFGEAFERI WNGDAENDGFNRLILAAGLHWRQVALLRGYCKYLLQTATPFSQAYVEATFTRYPLLARLL VELFEARFDPSTGGETKAQILAGQERLREQLSVLADGDEATLKALEPVLQARGSDRAAQQ EATRATLLKLMDRVSSLDEDRILRSFIDVIDATLRTNYYQTSKDGKHGHCISFKLDSSLV PDLPKPRPYREIFVYGPRVEGVHLRFGAVARGGLRWSDRREDFRTEVLGLVKAQMVKNTV IVPVGAKGGFYVKRSPVGGDRDAIQAEGIACYKLFIQSLLDITDNIVGGKIVPPTQVVRH DQDDPYLVVAADKGTATFSDIANGLALDHGFWMGDAFASGGSVGYDHKGMGITARGAWES VKRHFRALGRDCQSQDFSVVGIGDMSGDVFGNGMLLSRHIRLLAAFDHRHIFLDPNPDAA VSFAERERLFALPRSSWADYDAKLISAGGGIYPRTLKSIELSAPVREALGLDASVKQLSP NELMNAILKAPVDLFWNGGIGTYVKASSESHGDVGDRANNGLRVNGGELRCKVVGEGGNL GLTQLGRIEAAQTGVLLNTDFIDNSAGVDTSDHEVNIKILLNDVVQAKKLTYDARNKLLA SMTNEVADLVLWDNYRQNQAISLMERMSVKRLGSKQHFIRTLELQGLLDRQIEYLPSDAE LSARKARGQGMTRPELSVLLSYSKLVAFQQLLESDIPEDPYLSKELQRYFPQPLQKKYAD AMERHRLKREIIATAVTNTTINRMGATFLMRMQEDTGRSIAEVAKAYTISRETLDARALW TQIDALDGKVPESVQIDALEVIWRLQRSFVRWLLSRPGQMPGITAAVERYHGPFNDIRVA SGVLPDSQRPVYEASVQEWQEKGLTPELAQQLCELRYLEPAFDIIELARTRKLKPVEVSK VHFRLGEALRLPWLFEQIDALEVNGRWHAVARGVLRDELAAHQRTLAGQVLSMPGASAED KVANWLARDDSSLRFTLAMLSDVAEQKTLDYPTVSVAVQRLGQLAAHGV