Protein Info for Xcc-8004.2114.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: histidine kinase/response regulator hybrid protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1002 PF08448: PAS_4" amino acids 102 to 212 (111 residues), 27.5 bits, see alignment E=9.3e-10 amino acids 228 to 340 (113 residues), 30.9 bits, see alignment E=8.6e-11 amino acids 380 to 468 (89 residues), 25.6 bits, see alignment E=3.7e-09 amino acids 498 to 610 (113 residues), 62.7 bits, see alignment E=1.1e-20 TIGR00229: PAS domain S-box protein" amino acids 348 to 473 (126 residues), 32.8 bits, see alignment E=3.3e-12 PF00512: HisKA" amino acids 633 to 697 (65 residues), 33.2 bits, see alignment 1.3e-11 PF02518: HATPase_c" amino acids 741 to 860 (120 residues), 75.6 bits, see alignment E=1.3e-24 PF00072: Response_reg" amino acids 886 to 998 (113 residues), 56.7 bits, see alignment E=7.7e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to xcb:XC_1686)

Predicted SEED Role

"histidine kinase/response regulator hybrid protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X842 at UniProt or InterPro

Protein Sequence (1002 amino acids)

>Xcc-8004.2114.1 histidine kinase/response regulator hybrid protein (Xanthomonas campestris pv. campestris strain 8004)
MPHAGSLHGESLTPWSMHDAVDRPPFDGKTHRARLPYFRQWSTPTTSDAMPVDPSGDSFS
FLAGGGEMGARMRAHDWSGSALGLPSQWPQSLRSALSICLNSPVLATVLWGPDLVMLYND
AYIPSMADRHPWALGQPVSEVWGASWEQVAPPFRRCLQTGEGFEQRHVELPMVRRGVPET
TYWNFSAAPIRGEDGSIVGLFNQGIEITETVRADRLRAAEAERQRRLFEQAPGFTAILHG
PEHVFAFVNAAYLRLVGGRDMLGMSVRAGLPELEGQGFYELLDSVYSTGERFVASAVSIQ
LQRTGTGAEQRFVDFVYEPVKDDAGRVTGIFVQGFDTTDAQQAQQALRESEKRYRMLFEN
IDAGFCIAEVKFDAQGQAIDHRMLAVNPAFERHTGLTDVVGKWSSQLLPGIEQEWHEAYG
RVARSGEPLRFEREAARLGRWYDAHLFPAGTHDNHVAMLIVDITPRRRVEQQLRDLNETL
EQRVVEALAERRLFADFVDSTDAAVLACDMDFTILALNTASAEALRLAYGVSAHVGDNLL
GLLDGLPEHRAQVARHWGRALSGDEFLVLEEFGDPARALRHYEVRFSQLRDRHGGRVGAF
QVAQDVTDRVQTEASLEVAREALRQSQKMEAVGQLTGGLAHDFNNLLTGISGSLELMQTR
MGQGRFDDVECYIAVAQKAAGRAAALTHRLLAFSRRQTLAPKPTDVNALIAGMEDLIRRT
VGPSIELTTVAEQALWPALVDPSQLENALLNLCLNARDAMPDGVRITIETSNSWLNHSAT
QQNEVPDGEYLSLCVSDTGTGMPEDVIARVFEPFFTTKPIGEGTGLGLSMIYGFAQQSGG
QVRVSSTVGEGTTVCIHLPRHLGDATGDAQARTLPAMPRSQQGETVLVVDDEPSVRMLVA
DILEELGYTALQAVDGASGLSVLQSDVRIDLLITDVGLPGGMNGRQMADAARIARPRLSV
LFITGYAETAVLGAGQLAPGMAVLTKPFGIDAMAARIREMIR