Protein Info for Xcc-8004.1440.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: 4-hydroxybenzoyl-CoA thioesterase family active site

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 152 TIGR02799: tol-pal system-associated acyl-CoA thioesterase" amino acids 16 to 140 (125 residues), 171.3 bits, see alignment E=1e-54 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family" amino acids 19 to 122 (104 residues), 109.4 bits, see alignment E=1.3e-35 PF13279: 4HBT_2" amino acids 22 to 122 (101 residues), 53.2 bits, see alignment E=4.3e-18 PF03061: 4HBT" amino acids 30 to 114 (85 residues), 59.1 bits, see alignment E=4.5e-20

Best Hits

Swiss-Prot: 45% identical to YBGC_ECOLI: Acyl-CoA thioester hydrolase YbgC (ybgC) from Escherichia coli (strain K12)

KEGG orthology group: K07107, acyl-CoA thioester hydrolase [EC: 3.1.2.-] (inferred from 100% identity to xcb:XC_1137)

Predicted SEED Role

"4-hydroxybenzoyl-CoA thioesterase family active site" in subsystem Ton and Tol transport systems

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.2.-

Use Curated BLAST to search for 3.1.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X6N6 at UniProt or InterPro

Protein Sequence (152 amino acids)

>Xcc-8004.1440.1 4-hydroxybenzoyl-CoA thioesterase family active site (Xanthomonas campestris pv. campestris strain 8004)
MTADSRLPIPQSPPVFSWPTRVYWEDTDAGGVVYHARYVAFMERARTEWMRALGFGQERL
RQQHDLVFAVRSMQLDFLKPARLDDALSVSAVLTRCKRASLIFAQSVRREGEVLLTAEVR
IAALGGSDFRPRGMDDALFDALKALETTESDY