Protein Info for Xcc-8004.1433.1 in Xanthomonas campestris pv. campestris strain 8004
Annotation: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to xca:xccb100_1168)Predicted SEED Role
"Cob(I)alamin adenosyltransferase (EC 2.5.1.17)" in subsystem Cobalamin synthesis or Coenzyme B12 biosynthesis (EC 2.5.1.17)
MetaCyc Pathways
- superpathway of adenosylcobalamin salvage from cobinamide I (8/8 steps found)
- adenosylcobinamide-GDP biosynthesis from cobyrinate a,c-diamide (6/6 steps found)
- superpathway of adenosylcobalamin salvage from cobinamide II (8/9 steps found)
- adenosylcobalamin salvage from cobalamin (5/5 steps found)
- adenosylcobinamide-GDP salvage from cobinamide I (5/5 steps found)
- adenosylcobinamide-GDP salvage from cobinamide II (5/6 steps found)
- cobalamin salvage (eukaryotic) (4/8 steps found)
- adenosylcobalamin biosynthesis II (aerobic) (21/33 steps found)
- adenosylcobalamin biosynthesis I (anaerobic) (20/36 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.5.1.17
Use Curated BLAST to search for 2.5.1.17
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0H2X6S0 at UniProt or InterPro
Protein Sequence (219 amino acids)
>Xcc-8004.1433.1 Cob(I)alamin adenosyltransferase (EC 2.5.1.17) (Xanthomonas campestris pv. campestris strain 8004) MSGGDDQQTQSGHPEAASADVLLVHGIWNTAHWLLPLARRLRTAGMTPALFGYASVRGGP AQAVPQLIARLRATRAPLLVCHSLGGLMALQALQQAPELPVQRVVCLGSPLCGSAAARGL ARRGGHWAMGRSAALLQRGFTHWDGAAQVGQIAGCVPRGLGRWLAPLQAGSDGTVGLDET GLPGLHDHCVVQASHSGLLRSPAAAQQVLAFLRDGRFTH