Protein Info for Xcc-8004.1209.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: D-galactarate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 transmembrane" amino acids 12 to 28 (17 residues), see Phobius details amino acids 49 to 72 (24 residues), see Phobius details amino acids 81 to 99 (19 residues), see Phobius details amino acids 105 to 123 (19 residues), see Phobius details amino acids 144 to 166 (23 residues), see Phobius details amino acids 173 to 191 (19 residues), see Phobius details amino acids 248 to 270 (23 residues), see Phobius details amino acids 283 to 304 (22 residues), see Phobius details amino acids 323 to 341 (19 residues), see Phobius details amino acids 347 to 368 (22 residues), see Phobius details amino acids 380 to 402 (23 residues), see Phobius details amino acids 408 to 429 (22 residues), see Phobius details signal peptide" amino acids 29 to 29 (1 residues), see Phobius details PF07690: MFS_1" amino acids 19 to 312 (294 residues), 179.4 bits, see alignment E=1e-56 TIGR00893: D-galactonate transporter" amino acids 21 to 430 (410 residues), 484.7 bits, see alignment E=1e-149 PF00083: Sugar_tr" amino acids 22 to 430 (409 residues), 37.5 bits, see alignment E=1.4e-13

Best Hits

Swiss-Prot: 65% identical to GUDP_BACSU: Probable glucarate transporter (gudP) from Bacillus subtilis (strain 168)

KEGG orthology group: K03535, MFS transporter, ACS family, glucarate transporter (inferred from 100% identity to xca:xccb100_0942)

MetaCyc: 66% identical to galactarate/D-glucarate transporter GudP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-203; TRANS-RXN0-204; TRANS-RXN0-523

Predicted SEED Role

"D-galactarate permease" in subsystem D-galactarate, D-glucarate and D-glycerate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X6C7 at UniProt or InterPro

Protein Sequence (453 amino acids)

>Xcc-8004.1209.1 D-galactarate permease (Xanthomonas campestris pv. campestris strain 8004)
MAPDSKTVPRRRYLILLMLFVVTTINYADRATLSIAGSAVQDSLGIDALQMGFIFSAFGW
AYVAGQIPGGWLLDRFGSRRVYGLSLLTWSLFTVLQGFIGWVPVAWAVTTLFVLRFLVGI
AEAPSFPGNSRIVAAWFPTAERGLAASIFNSAQYFATVAFAPLMGWLVHAWGWEHVFLVM
GAAGVLLAALWRKTIYAPREHPRLSAQELDYIQRNGALVDMEQRNTPSQHVKGAQWHYAK
QLLGNRMLLGVYIGQYCITTLTYFFLTWFPVYLVKERGMSILEAGFVASLPAVCGFIGGV
LGGYVSDRMVRRGYSLTVARKTPIVVGMLMSVTMIGCNYVQAEWMVVGLMALAFFGKGIG
ALGWAVVADTSPKEIAGLSGGLFNTFGNMAGITTPIVIGYIVSNTGTFEWALVFVGFNAL
LAVVSYLVVVGQIKRVELKAPPGGPSMPLPAAL