Protein Info for Xcc-8004.1117.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00707: transaminase, acetylornithine/succinylornithine family
  • amino acids 27 to 413 (387 residues), 466.9 bits, E=2.2e-144
• PF00202: Aminotran_3
  • amino acids 33 to 412 (380 residues), 394.4 bits, E=5.2e-122
• PF00155: Aminotran_1_2
  • amino acids 186 to 345 (160 residues), 20 bits, E=3.5e-08

Best Hits

Swiss-Prot: 100% identical to ARGD_XANCP: Acetylornithine aminotransferase (argD) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K00821, acetylornithine/N-succinyldiaminopimelate aminotransferase [EC: 2.6.1.11 2.6.1.17] (inferred from 100% identity to xca:xccb100_0902)

MetaCyc: 49% identical to succinylornithine transaminase subunit (Pseudomonas aeruginosa)
Succinylornithine transaminase. [EC: 2.6.1.81]; Ornithine aminotransferase. [EC: 2.6.1.81, 2.6.1.13]; Acetylornithine transaminase. [EC: 2.6.1.81, 2.6.1.13, 2.6.1.11]

Predicted SEED Role

No annotation

MetaCyc Pathways

• superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
• aspartate superpathway (21/25 steps found)
• L-arginine biosynthesis III (via N-acetyl-L-citrulline) (9/9 steps found)
• L-lysine biosynthesis I (9/9 steps found)
• L-arginine biosynthesis I (via L-ornithine) (8/9 steps found)
• L-ornithine biosynthesis I (5/5 steps found)
• L-arginine degradation VI (arginase 2 pathway) (4/4 steps found)
• L-arginine degradation I (arginase pathway) (3/3 steps found)
• L-ornithine biosynthesis II (3/3 steps found)
• L-proline biosynthesis III (from L-ornithine) (3/3 steps found)
• L-arginine biosynthesis II (acetyl cycle) (8/10 steps found)
• L-citrulline biosynthesis (6/8 steps found)
• L-N^δ-acetylornithine biosynthesis (5/7 steps found)
• superpathway of arginine and polyamine biosynthesis (12/17 steps found)
• L-arginine degradation XIII (reductive Stickland reaction) (3/5 steps found)
• superpathway of L-citrulline metabolism (8/12 steps found)
• L-arginine degradation II (AST pathway) (1/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Lysine biosynthesis
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.11, 2.6.1.13, 2.6.1.17, 2.6.1.81

Use Curated BLAST to search for 2.6.1.11 or 2.6.1.13 or 2.6.1.17 or 2.6.1.81

Sequence Analysis Tools

See A0A0H2X665 at UniProt or InterPro

Protein Sequence (420 amino acids)

>Xcc-8004.1117.1 hypothetical protein (Xanthomonas campestris pv. campestris strain 8004)
MPVSLRFRDPAIMSTAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDQGREYLDLSSG
IAVSGLGHNDPDLMAALTEQAGKLWHTSNVFFSAPPLKLAEELVTASRFAQKVFLCNSGT
EANEAAIKLVRKWASSQGRPADKRVIVTFRGSFHGRTLASVTATAQPKYQEGYEPLPGGF
RYVDFNDVPALESAMASGDVAAVMLEPIQGEGGVMPAAPGFLARVRALCDQHDALLVLDE
IQCGMGRTGSLFAHWQEQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGG
NPLAAAVARVALRKLASPQIAENVARQSAALRAGLEALNAEFGVFAQIRGRGLMLGAVLA
PAHAGQAGAILDLAAAHGLLLLQAGPDVLRFVPALNLTDAELADGLARLRLAIAAYVAQH