Protein Info for TX73_024710 in Rhodopseudomonas palustris CGA009

Annotation: DNA-3-methyladenine glycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 239 PF00730: HhH-GPD" amino acids 49 to 190 (142 residues), 42.8 bits, see alignment E=3e-15

Best Hits

KEGG orthology group: K01247, DNA-3-methyladenine glycosylase II [EC: 3.2.2.21] (inferred from 100% identity to rpa:RPA4755)

Predicted SEED Role

"DNA-3-methyladenine glycosylase II (EC 3.2.2.21)" in subsystem DNA Repair Base Excision (EC 3.2.2.21)

Isozymes

Compare fitness of predicted isozymes for: 3.2.2.21

Use Curated BLAST to search for 3.2.2.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (239 amino acids)

>TX73_024710 DNA-3-methyladenine glycosylase (Rhodopseudomonas palustris CGA009)
MTIHLDSQADLEDAITTLVKRDPRLKPVLQVAGMPALRRREPGFAGLAAIVCGQQLSTAS
AAAIWGRVSAAFEPFEHDAIKRARADRLARLGLSTAKIKTLKALAKELAAERLNLDVLAE
EDADAAHATLTALHGIGPWTADIYLLFCLGHGDAWPAGDLAVQEAMRIGLGLKARPTVKQ
MAPLAEPWRPLRGAAAHLWWAYYHAVKRREGVIGDDKAAKVVAKKVTAKTPRARKSPSR