Protein Info for TX73_015220 in Rhodopseudomonas palustris CGA009

Annotation: NADH-quinone oxidoreductase subunit NuoN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01770: proton-translocating NADH-quinone oxidoreductase, chain N
  • amino acids 11 to 467 (457 residues), 482.8 bits, E=6.6e-149
• PF00361: Proton_antipo_M
  • amino acids 127 to 418 (292 residues), 285.9 bits, E=3.6e-89

Best Hits

Swiss-Prot: 64% identical to NUON_AZOC5: NADH-quinone oxidoreductase subunit N (nuoN) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K00343, NADH dehydrogenase I subunit N [EC: 1.6.5.3] (inferred from 100% identity to rpt:Rpal_3285)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

• aerobic respiration III (alternative oxidase pathway) (3/3 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (1/2 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Protein Sequence (479 amino acids)

>TX73_015220 NADH-quinone oxidoreductase subunit NuoN (Rhodopseudomonas palustris CGA009)
MNFETAGYPLLPILPELVLVVGAMLLLMLGAYRGPKATGTVTVLAILLLLATGALELFAL
PAGKLVTFGGSFIVDDFARFLKVLALIGSAVTLILSLEVLTDPSRRMFEYAILVLLSSAG
MLLLISAGDLIMLYLGLELMSLALYVVAASNRQDAKSNEAGMKYFVLGALSSGMLLYGAS
LIYGFTGTVQFSGIAAAAKDGNVGLVFGLVFLLAGLCFKVSAVPFHMWTPDVYEGAPTPV
TAFFASAPKVAGIAIFTRVTLTAFPSIAPQWQQIVIFVAIASMALGSFAAIGQKNIKRLM
AYSAIANIGFALVGLSAGTVEGAQGVIVYISIYVAMTLGAFAVILAMRRNGMHVENISDF
AGLSRTNPPLAFFFAMLLFSFAGIPPLAGFFAKFYVFMAAIKAGMFVLAVIGVVTSVVGA
YYYLAIVKVMYFDEPAPGVDPVRPELRGVLMVAGLFNMLFFVYPAPLVNAATAAAKSLF