Protein Info for TX73_014680 in Rhodopseudomonas palustris CGA009

Annotation: isoprenylcysteine carboxylmethyltransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 49 to 67 (19 residues), see Phobius details amino acids 88 to 105 (18 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 194 to 213 (20 residues), see Phobius details PF07298: NnrU" amino acids 57 to 192 (136 residues), 29 bits, see alignment E=4.1e-11

Best Hits

Swiss-Prot: 70% identical to MDDA2_BRADU: Methanethiol S-methyltransferase 2 (mddA2) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: None (inferred from 100% identity to rpa:RPA2835)

MetaCyc: 51% identical to methanethiol S-methyltransferase (Pseudomonas deceptionensis)
RXN-17813 [EC: 2.1.1.334]

Predicted SEED Role

"FIG01009173: hypothetical protein"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.334

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (266 amino acids)

>TX73_014680 isoprenylcysteine carboxylmethyltransferase family protein (Rhodopseudomonas palustris CGA009)
MIKRLLIPTYGLLSYAVFLVSMIYAPGFFGNTLVSKSIDVGAASSPGQAFLINLQLIGLF
AIQHSIMARQRFKQWWARHLPAPCQRSTYVLLTSLLLLLLFWQWRPIPVVVWSTSGIAAW
LLVGLYWMGWVLVLASTHMIDHLDLFGLRQSFSAMRGTEPLRPAFRTPLLYRLVRHPLML
GFLIVFWATPEMTAGHLLFAVVITIYILIALQFEERDLIAEFGATYQQYRERVPMLLPRV
LRRTAAGRGGAVPDESRATASPPSGG