Protein Info for TX73_013465 in Rhodopseudomonas palustris CGA009
Annotation: peptidylprolyl isomerase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 54% identical to PPI1_BRUME: Probable peptidyl-prolyl cis-trans isomerase (ppi) from Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
KEGG orthology group: None (inferred from 98% identity to rpx:Rpdx1_2869)MetaCyc: 51% identical to glucuronan lyase (Sinorhizobium meliloti Rm2011)
Glucuronan lyase. [EC: 4.2.2.14]
Predicted SEED Role
"Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)" in subsystem Queuosine-Archaeosine Biosynthesis (EC 5.2.1.8)
Isozymes
Compare fitness of predicted isozymes for: 5.2.1.8
Use Curated BLAST to search for 4.2.2.14 or 5.2.1.8
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (187 amino acids)
>TX73_013465 peptidylprolyl isomerase (Rhodopseudomonas palustris CGA009) MIRLIGIFAALLFALPALAQPLPANLDKQNALVIDTTKGRIVIALRADIAPKHAERLKQL AREGFYNNVPFHRVMGGFMAQTGDGQNFNGTGGSKYPNLKQEFSNVPFTRGVVGMARRGD SVDSANSQFFIMFADGPSLNGQYTVIGNVVSGMDVVDKLKKASPTSPGGAVTDPDKMVKV QVASDVK