Protein Info for TX73_008355 in Rhodopseudomonas palustris CGA009

Annotation: histidine phosphotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 PF10090: HPTransfase" amino acids 92 to 211 (120 residues), 128.9 bits, see alignment E=4.7e-42

Best Hits

Swiss-Prot: 51% identical to CHPT_BRUA2: Protein phosphotransferase ChpT (chpT) from Brucella abortus (strain 2308)

KEGG orthology group: K13588, histidine phosphotransferase ChpT (inferred from 100% identity to rpa:RPA1626)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>TX73_008355 histidine phosphotransferase family protein (Rhodopseudomonas palustris CGA009)
MSDTQSPAVQAPAPDALELAALLCSRVCHDLISPVGAIVNGLEVLDDSSKQEDRDFALEL
IRKSAKTASARLQFCRLAFGAAGSAGAQIDLGDAQNMARGHLEDDKTKLTWNLPRLLLAK
NRVKLLLNMLVIAQQTIPRGGTLTIDPIGEGDNLSFRIVAAGINARTPHNIVDLLNGTQS
GPIESHGVQPYYTRLLAQACGLTVSLAPEGDTMVVTAS