Protein Info for TX73_005760 in Rhodopseudomonas palustris CGA009

Annotation: EAL domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 776 transmembrane" amino acids 21 to 47 (27 residues), see Phobius details amino acids 53 to 71 (19 residues), see Phobius details amino acids 97 to 115 (19 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 147 to 164 (18 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 260 to 271 (12 residues), see Phobius details PF12860: PAS_7" amino acids 217 to 328 (112 residues), 57.6 bits, see alignment E=2.7e-19 PF08448: PAS_4" amino acids 217 to 325 (109 residues), 24 bits, see alignment E=7.6e-09 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 333 to 494 (162 residues), 131.9 bits, see alignment E=9.6e-43 PF00990: GGDEF" amino acids 335 to 492 (158 residues), 151.8 bits, see alignment E=2.9e-48 PF00563: EAL" amino acids 514 to 744 (231 residues), 234.1 bits, see alignment E=3.1e-73

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpt:Rpal_1312)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (776 amino acids)

>TX73_005760 EAL domain-containing protein (Rhodopseudomonas palustris CGA009)
MQLASQKRNSEQTSPAIRAGLVDSLFMNPAPMIVGAFGPAIAGAVIGLVTGSILNWLCVP
LFVLIGFARAVQMRRYQQRNAPLTVEEADVWERRYRLGAIAHGISLGAWSLVVLLGTDDS
AAHMLCVATVVAYTSAGVGRTFGRPQIFHLQVLLSCGPLIFAMVRVGGVYYLTLALLSAV
FFISIRHLTSSLQRIYLNAWIGREREAALANQFDTALNNMPHGLCMFRADGRLAVMNHRF
AEMMRLRDELVKGSPTATEIVSACVAIGAISAASGRLILSEIESALAGEIVTVGDETIPR
SLCWTFQPMADGGAVVLIEDITERRNAEARIVHLARYDELTALPNRVSFRDEIERILEAE
HGRGKTRLSALLFIDLDQFKQINDTLGHPCGDRLLCSVAERLRDMLRPDDYVARFGGDEF
VVFQQNIASNEDAAALARRIVDRLSDRYLIDHHVVEIGASIGIAMTSPGTKADILLKNAD
MALYRAKADGRGNYCFFREEMAQTVEARRILELDLRKALANEEFELYYQPLVNLKSGKIT
TCEALLRWNHPVRGTVSPVDIIPVAEDMGLIVDLGRWILRKACMECMLWPEPVSVAINFS
PQQFHQRDVLTEVRYALEVSGLPASRLEIEITESSLLRNTQWTHDALQQLHAEGVRISLD
DFGTGYSSLSYLHSFPLQKVKIDRSFLEGIDSDRPLTLLRGVARLSSDLGMSVVVEGIET
NEQLELISADGTVTEAQGYLFSRPVPAQRIRQLLNASQGVRQKDGKVLSLPTRSIA