Protein Info for TX73_004175 in Rhodopseudomonas palustris CGA009

Annotation: DMT family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 45 to 65 (21 residues), see Phobius details amino acids 77 to 98 (22 residues), see Phobius details amino acids 104 to 126 (23 residues), see Phobius details amino acids 135 to 153 (19 residues), see Phobius details amino acids 159 to 180 (22 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details amino acids 221 to 242 (22 residues), see Phobius details amino acids 250 to 273 (24 residues), see Phobius details amino acids 282 to 297 (16 residues), see Phobius details PF00892: EamA" amino acids 21 to 149 (129 residues), 87.1 bits, see alignment E=5.9e-29 amino acids 162 to 296 (135 residues), 52.6 bits, see alignment E=2.8e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA0810)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>TX73_004175 DMT family transporter (Rhodopseudomonas palustris CGA009)
MSLTPAVPLASPLFNPRALQIVLFCALWSFAFVAGKVGVSDCPPLILLAARFSLAGILIL
GISALRREPWTLRPRDVAICALLGLANNALYLGLGYVGLQTVSAGIGGLIVSANPVFTAV
AAALLLHEALTWRKIAGLVLGVAGVAFIVWHRVAIGAEAWTGLGFTLASLASIVAGTILF
KRLAPRGSLWIGNGIQNLAAGLALTPLAMSLSSVSDIVPSWRLAGAFAFLVLGGSIVAYW
LWFRLLTLYGATAASAWHFVMPPLAMLFAWLVLGESIDGRDLLGVIPVAIGIYLVTRPAR
IAAPAS