Protein Info for Synpcc7942_2454 in Synechococcus elongatus PCC 7942

Name: apt
Annotation: adenine phosphoribosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 transmembrane" amino acids 199 to 222 (24 residues), see Phobius details amino acids 243 to 264 (22 residues), see Phobius details amino acids 284 to 303 (20 residues), see Phobius details amino acids 346 to 367 (22 residues), see Phobius details amino acids 387 to 411 (25 residues), see Phobius details TIGR01090: adenine phosphoribosyltransferase" amino acids 3 to 158 (156 residues), 213.5 bits, see alignment E=1e-67 PF00156: Pribosyltran" amino acids 46 to 148 (103 residues), 45.9 bits, see alignment E=3.8e-16 PF00528: BPD_transp_1" amino acids 213 to 419 (207 residues), 137.2 bits, see alignment E=5.6e-44

Best Hits

KEGG orthology group: K00759, adenine phosphoribosyltransferase [EC: 2.4.2.7] (inferred from 100% identity to syf:Synpcc7942_2454)

Predicted SEED Role

"Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.2.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31KD5 at UniProt or InterPro

Protein Sequence (424 amino acids)

>Synpcc7942_2454 adenine phosphoribosyltransferase (Synechococcus elongatus PCC 7942)
MDLKTLIREIPDFPKPGILFRDYTTVLKDPQGWRYSIDRLTELIKPLEPTAIVGIESRGF
ILGAPLAYQLGLGFVPVRKPGKLPADTHSVEYELEYGSDRLEIHQDALAPGDRVVVVDDL
IATGGTASATATLIDRCSATLAGFAFVIELEGLNGRDRPWLEQYGRWLWQVVRYGNFGSS
FVYQRPVADLLWERVPNTLLLAICSLITTWAIALPLGIQAAVAQNQRSDRILQLISYLGQ
GTPSFITALLLLFLAQFLTPLLPIGGMTSLDFEDLTPLQQMADLGRHLILPVLALTLSGF
ASLQRISRGEMLEVLRQDYIRTARAKGLPEQRVIYVHALRNAINPLITLLGFEFATLLSG
AFIAEYFFNWPGLGRLILQAVFAQDLYLVMASLMMGAVMLILGNLLADLLLRWVDPRIRL
DDLN