Protein Info for Synpcc7942_2258 in Synechococcus elongatus PCC 7942

Name: avtA
Annotation: valine--pyruvate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00155: Aminotran_1_2
  • amino acids 38 to 412 (375 residues), 104.5 bits, E=3.6e-34

Best Hits

KEGG orthology group: K00835, valine--pyruvate aminotransferase [EC: 2.6.1.66] (inferred from 100% identity to syf:Synpcc7942_2258)

Predicted SEED Role

"Valine--pyruvate aminotransferase (EC 2.6.1.66)" in subsystem Alanine biosynthesis or Branched-Chain Amino Acid Biosynthesis or Pyruvate Alanine Serine Interconversions (EC 2.6.1.66)

MetaCyc Pathways

• superpathway of L-alanine biosynthesis (4/4 steps found)
• L-alanine biosynthesis I (2/2 steps found)

KEGG Metabolic Maps

• Valine, leucine and isoleucine biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.66

Sequence Analysis Tools

See Q31KY1 at UniProt or InterPro

Protein Sequence (427 amino acids)

>Synpcc7942_2258 valine--pyruvate transaminase (Synechococcus elongatus PCC 7942)
MSLESLSRYGRQMSQLTGVRAIMKDIIETLRSGQGQTFINLSAGNPVVLPEVEQLWRDCT
ADLLGSAEYGQVVGRYGTSQGYEPLIAAIIQEFNQRYGWSISDRNILITPGSQSLYFLAA
NAFGGWAEDGSLRKILLPLSPDYTGYGGVCLEPQAVVAARPQIERIGDHRFKYRPDFEQL
QIGADTGMLLFSRPCNPTGNVISDAELERLATLAAAQNVPVFVDSAYAPPFPGLNFTEMT
PFFGDNIVHCLSLSKAGLPGERLGIAIGPEPVIQVLEAFQTNLCIHSSRYGQAIAARAIA
SGQLTAIAETVIRPYYAAKFARVERQLDALLPDSLPWRLHQGEGGIFAWLWLEEAPLDDW
QIYQQLKQAGVIVVPGSSFFPGLREDWVHTRQCLRISLAAEDHELETGMERLATTVQQIY
RQAPIPA