Protein Info for Synpcc7942_2202 in Synechococcus elongatus PCC 7942

Name: mcrA
Annotation: HNH nuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 PF14279: HNH_5" amino acids 79 to 131 (53 residues), 56.3 bits, see alignment E=3.6e-19 PF01844: HNH" amino acids 79 to 122 (44 residues), 59.3 bits, see alignment E=5e-20 PF13395: HNH_4" amino acids 87 to 124 (38 residues), 29.3 bits, see alignment 1e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to syf:Synpcc7942_2202)

Predicted SEED Role

"HNH endonuclease family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31L37 at UniProt or InterPro

Protein Sequence (165 amino acids)

>Synpcc7942_2202 HNH nuclease (Synechococcus elongatus PCC 7942)
MGKVLVLNASYEPLNITSWRRAVILLLKDKAESLEHNGRMILPDLPLPTVIRLRQYVRIP
YNEIPLTRRNVLHRDGHSCQYCGYHGENLTLDHILPRSRGGADTWENVITACMRCNVHKG
NRTPKEAGMPLMSTPRQPVSSLYFEISRYLNQGSHQEWRKYVIGA