Protein Info for Synpcc7942_1858 in Synechococcus elongatus PCC 7942
Name: ho1
Annotation: Heme oxygenase (decyclizing)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 72% identical to HO1_SYNY3: Heme oxygenase 1 (pbsA1) from Synechocystis sp. (strain PCC 6803 / Kazusa)
KEGG orthology group: K00510, heme oxygenase [EC: 1.14.99.3] (inferred from 100% identity to syc:syc2236_c)MetaCyc: 72% identical to heme oxygenase 1 (Synechocystis sp. PCC 6803)
RXN-17523 [EC: 1.14.15.20]
Predicted SEED Role
"Heme oxygenase (EC 1.14.99.3)" in subsystem Bilin Biosynthesis or Heme, hemin uptake and utilization systems in GramPositives or Oxygen and light sensor PpaA-PpsR (EC 1.14.99.3)
MetaCyc Pathways
- phycocyanobilin biosynthesis (3/3 steps found)
- heme degradation II (1/1 steps found)
- phycoviolobilin biosynthesis (3/4 steps found)
- phycoerythrobilin biosynthesis II (2/3 steps found)
- phycoerythrobilin biosynthesis I (2/4 steps found)
- phytochromobilin biosynthesis (1/3 steps found)
- phycourobilin biosynthesis (2/5 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.14.15.20 or 1.14.99.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q9Z3G6 at UniProt or InterPro
Protein Sequence (238 amino acids)
>Synpcc7942_1858 Heme oxygenase (decyclizing) (Synechococcus elongatus PCC 7942) MGANLATKLREGTKKAHTMAENVGFVKCFLKGVVEKNSYRKLVANLYFVYSAMEEELERH RDNDKIAGIYFPVLNRKTSLERDLAFYYGEDWRQQIQPSKAAQSYVARIREVSNTAPELL VGHAYTRYLGDLSGGQILKTIAQRGMNLDGAGTAFYEFEAIEDEKAFKQTYRQAMDTLPV DEATADRIVEEANDAFGMNMAMFQELEGNLVAAIGKMFFNSLTRRFVRGSTELATAAE