Protein Info for Synpcc7942_1722 in Synechococcus elongatus PCC 7942

Name: sbpA
Annotation: Thiosulphate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details TIGR00971: sulfate ABC transporter, sulfate-binding protein" amino acids 54 to 358 (305 residues), 295.7 bits, see alignment E=2.1e-92 PF13531: SBP_bac_11" amino acids 59 to 312 (254 residues), 140.3 bits, see alignment E=8.6e-45 PF01547: SBP_bac_1" amino acids 74 to 304 (231 residues), 62 bits, see alignment E=9.8e-21

Best Hits

Swiss-Prot: 53% identical to SUBI_SYNY3: Sulfate-binding protein (sbpA) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K02048, sulfate transport system substrate-binding protein (inferred from 100% identity to syf:Synpcc7942_1722)

MetaCyc: 46% identical to sulfate/thiosulfate ABC transporter periplasmic binding protein Sbp (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate and thiosulfate binding protein CysP" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31MG7 at UniProt or InterPro

Protein Sequence (361 amino acids)

>Synpcc7942_1722 Thiosulphate-binding protein (Synechococcus elongatus PCC 7942)
MAFRSFLPLRPGIKRSLAGGLAAAIAAGSFATTAGARSAQTSAAGATPQQVAQAKQELVL
VSYAVTKAAYDRIIPKFTAKWKKEKGQDVTIRGSYGGSGSQTRAILDGLEADIAALALES
DTARLERAGLIGKNWQRRLPNNSNLSSSVVVICTRKGNPKKIKGWADLAKPGVRIVTANP
KTSGGARWNFLALYGSVAKNGGTDKQAFDFVKKVYDNVPVLAKDARESTDIFYKKNQGDV
LLNYENEVILARLNGEDVGTCITPQVNIAIETPIAVVDKVANKRKTKAIADAFTRFVFTP
EAQEELAKVGFRPANAAVAQKYRKNFPPLTKLYNIKSFGGWAAADKKFFADGGVFDQIQG
R