Protein Info for Synpcc7942_1308 in Synechococcus elongatus PCC 7942

Name: trpS
Annotation: tryptophanyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 355 TIGR00233: tryptophan--tRNA ligase" amino acids 21 to 350 (330 residues), 381.3 bits, see alignment E=2.1e-118 PF00579: tRNA-synt_1b" amino acids 21 to 305 (285 residues), 280.1 bits, see alignment E=1.1e-87

Best Hits

Swiss-Prot: 76% identical to SYW_SYNY3: Tryptophan--tRNA ligase (trpS) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K01867, tryptophanyl-tRNA synthetase [EC: 6.1.1.2] (inferred from 100% identity to syf:Synpcc7942_1308)

Predicted SEED Role

"Tryptophanyl-tRNA synthetase (EC 6.1.1.2)" (EC 6.1.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31NN1 at UniProt or InterPro

Protein Sequence (355 amino acids)

>Synpcc7942_1308 tryptophanyl-tRNA synthetase (Synechococcus elongatus PCC 7942)
VKSSGTIVLCSHLDSACPMGKPRVLSGVQPTGNLHLGNYLGAIRNWVEGQQQYDNFFCVV
DLHAITVPHEAASLAENTYRTAALYLACGIDLSCSTIFVQSHVPAHSELTWLLNCITPLN
WLEGMIQFKEKALKQGENVSTGLLDYPVLMAADILLYDADRVPVGEDQKQHLELTRDIAV
RINHLFGRDDTPIFKLPEPLIPKAGARVMSLTDGTKKMSKSDPTELSRINLLDPPELIEK
KVKRCKTDPQRGLEFDNPDRPECNNLLSLYAILSGRSRETVAAECADMGWGQFKPLLAEA
AIEALRPIQTKYEEVRSEPGYLDSVLKQGRERASEVANATLRRVQDALGFSRPVA