Protein Info for Synpcc7942_0513 in Synechococcus elongatus PCC 7942

Annotation: ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 TIGR04406: LPS export ABC transporter ATP-binding protein" amino acids 12 to 249 (238 residues), 333.9 bits, see alignment E=2.3e-104 PF00005: ABC_tran" amino acids 27 to 175 (149 residues), 117.6 bits, see alignment E=3.2e-38

Best Hits

Swiss-Prot: 57% identical to LPTB_ACIFR: Lipopolysaccharide export system ATP-binding protein LptB (lptB) from Acidithiobacillus ferrooxidans

KEGG orthology group: K06861, lipopolysaccharide export system ATP-binding protein [EC: 3.6.3.-] (inferred from 100% identity to syf:Synpcc7942_0513)

MetaCyc: 53% identical to lipopolysaccharide transport system ATP-binding protein LptB (Helicobacter pylori 26695)
RXN-23614 [EC: 7.5.2.5]

Predicted SEED Role

"Lipopolysaccharide ABC transporter, ATP-binding protein LptB" in subsystem KDO2-Lipid A biosynthesis

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.- or 7.5.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31QX4 at UniProt or InterPro

Protein Sequence (250 amino acids)

>Synpcc7942_0513 ATPase (Synechococcus elongatus PCC 7942)
LPSTAAIAVKIRLENVRKSYGKRLIVNRVSLSVAQGEVVGLLGPNGAGKTTTFYMTTGLE
RPDEGHVWLDETELTRLPMTQRARLGIGYLAQEASIFRHLTVVENLLLVLQQTGIRGREQ
RQRVEELLSEFRLEKVAHTQGIRVSGGERRRTEIARALAVGSQGPKFLLLDEPFAGIDPI
AVAEVQEIIARLRAQQMGILITDHNVRETLKITDRAYILRDGEILAAGSAEELASNPLVR
QYYLGEDFVF