Protein Info for Synpcc7942_0498 in Synechococcus elongatus PCC 7942

Annotation: mannose-1-phosphate guanyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 837 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF00483: NTP_transferase" amino acids 3 to 231 (229 residues), 171.4 bits, see alignment E=8e-54 PF12804: NTP_transf_3" amino acids 3 to 155 (153 residues), 36.7 bits, see alignment E=1.5e-12 PF02878: PGM_PMM_I" amino acids 383 to 513 (131 residues), 72.1 bits, see alignment E=1.1e-23 PF02879: PGM_PMM_II" amino acids 541 to 631 (91 residues), 38.7 bits, see alignment E=3.6e-13

Best Hits

KEGG orthology group: K00966, mannose-1-phosphate guanylyltransferase [EC: 2.7.7.13] K01840, phosphomannomutase [EC: 5.4.2.8] (inferred from 100% identity to syc:syc1022_c)

Predicted SEED Role

"Mannose-1-phosphate guanylyltransferase (EC 2.7.7.13 ) / Phosphomannomutase (EC 5.4.2.8)" in subsystem Mannose Metabolism or Alginate metabolism (EC 5.4.2.8)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.13, 5.4.2.8

Use Curated BLAST to search for 2.7.7.13 or 5.4.2.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31QY9 at UniProt or InterPro

Protein Sequence (837 amino acids)

>Synpcc7942_0498 mannose-1-phosphate guanyltransferase (Synechococcus elongatus PCC 7942)
MRAVLLAGGLGTRLRPLTCDRPKPMVPILNRPIAAHILQLLHRHGYQEILATLYYRPETI
QQYFQEGQDWGVDLRYILEADRPLGTAGSVKNLTSQLQETFLVASGDCLSDFDLTAALAW
HRQQQAIATVILARVDQPLEFGCVVCDRQQRIIRLIEKPDASELISDTVNSGFYILEPEA
LDYLPLDEPSDFATHLLPRLLAAGEVVTGYVDQGYWCDIGNRQAYQRAQLDALLGRVRLQ
ANQMEWRPGIYVGEGTTIASSAQLEPPLWIGQHCYIGEEVQLKAGTVIGDESRIEAGACL
DRAVVWNRVQIGQRSHLEGCVLADGVRLERHVQIHEGAVIGSGCRLQEEAQVQAEVRIWP
RKQIEAGAIVNLNLIWATSARRRLFSDGGVRGIANVDITPEFAVKLGVAYGSTIPPGSSV
TVSRDQRSISQMVTRSLIAGLMSTGITIRNLEAAAVPIARSMLARLPVVGGIHVRLDPLW
PTHVLIEFLDREGLTVDRALERRIEAAFFQEDLRRVPMQDLGTMITVSETLPLYRQLFCD
RLDRDLLLRSPNRIVIDYAYSVSGAVLPLLLSEFGCDAVILNASLRQQPPTENERQSLLE
QMGQVVSAIKANCGVQVAANGERFTLVDEQGMALDHEQLTVLMAEICWLRRPGGTVVVPM
TSSSAVDQTAWRYHGRVHRCRPTPTALMAACRNLPDVILGGSGELGFIFPEMHAGFDAIF
GIARLIEGLDRQSRSLSQWVESLPSIAHRHLTLSCPRNLLGTLMRQLLESHEPDRLNFQE
GLRIQGDRGDQWLLVLPDASYPLIHLYANAQDHQWVEQTLGSYQQQIEQFVATLQSP