Protein Info for Synpcc7942_0131 in Synechococcus elongatus PCC 7942

Annotation: cyclic nucleotide-binding domain (cNMP-BD) protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 941 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 71 to 90 (20 residues), see Phobius details amino acids 142 to 160 (19 residues), see Phobius details amino acids 166 to 186 (21 residues), see Phobius details amino acids 268 to 287 (20 residues), see Phobius details amino acids 326 to 347 (22 residues), see Phobius details amino acids 368 to 388 (21 residues), see Phobius details amino acids 398 to 416 (19 residues), see Phobius details PF00027: cNMP_binding" amino acids 830 to 915 (86 residues), 46.5 bits, see alignment E=1.5e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to syf:Synpcc7942_0131)

Predicted SEED Role

"cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31S06 at UniProt or InterPro

Protein Sequence (941 amino acids)

>Synpcc7942_0131 cyclic nucleotide-binding domain (cNMP-BD) protein (Synechococcus elongatus PCC 7942)
MLSQLPEQRMHWIRWILTVGWLLIIASLFYDPWTAKLTTPDHPWSPLRLSESCIQVQGNC
LSEQPYPLGTTLFWGAIVPASIFILLVFGHELWRRICPLSFLSQIPRSLGWQRQFRRENK
KTGKVRYELAKVRSDSWLGRNYPYVQFSWLFIGLCGRILFFNADRLVLAGWLLSTVAAAI
AVGYWYGGKSWCQYFCPMAPVQSIYSEPGGLLGSKAHTSEQLITQSMCRTFLPDGQEQSA
CVACQNPCIDIDAERNYWNSLSKPETGFIRYGYVGLVIGYFGYYYLYAGNWNYYFSGAWL
RQTDQLTSLFDPGIYLFGQAINVPKIIAVPLILGICTAIAYGGGRWLEKRAKSYYRRHPK
ELSLETIRHRIFTLCTFGIFNFFFIFGGRPLIQLFPWAVQYLYDLGLVTLSTLWLYKTWR
RSPDLYSRENLANRFRKQLEKLQLNVSQFLEGRTLNDLNTHEVYILAKVLPGFTREKRHQ
AYKGVVREALEEGYINYSSSLEVLQQMRQELGITDDEHRIVLEEVGIEDPSLLNPDRQRS
LENQIRLSGYRKSLERLLLLQSKQVAQGSLDPGSLQDSATIRSLRRQYSITSQDEEWILS
GLAGNASSVKRAEFLLAQLSQLIDCYRVLNQPVLYDHKAVLTLLRENISHKKELIVRSIL
ETLELLQSDPAALGLAQRLQQASPAILGEVLDQGHWSDRLPAAILQCLTQPGEMPVFCSL
EFSAQATLGHLETLLLDQNPMIQAAALYVIAQLDPERSQAIARDQRHPFNSPLVKATLEQ
LLALPSNASAHPSLTDFPMLERVVYLFNSDFFHRMQSETLIALADRAEVRTYSKGDLITE
AGDTCRELLLLIEGHANVHYQTGAEVRIEQLHPGQTLDELEVLAHSKSENTIVADSERTR
ILAISVDAFDDFLDHDPDFARRVLELESRQLQRFVRSMQSI