Protein Info for Synpcc7942_0023 in Synechococcus elongatus PCC 7942

Name: cax
Annotation: calcium/proton exchanger

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 354 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 93 to 113 (21 residues), see Phobius details amino acids 127 to 149 (23 residues), see Phobius details amino acids 162 to 181 (20 residues), see Phobius details amino acids 204 to 221 (18 residues), see Phobius details amino acids 240 to 263 (24 residues), see Phobius details amino acids 273 to 298 (26 residues), see Phobius details amino acids 304 to 325 (22 residues), see Phobius details amino acids 332 to 351 (20 residues), see Phobius details TIGR00378: calcium/proton exchanger" amino acids 11 to 350 (340 residues), 386.8 bits, see alignment E=5e-120 PF01699: Na_Ca_ex" amino acids 30 to 181 (152 residues), 62.3 bits, see alignment E=2.6e-21 amino acids 208 to 346 (139 residues), 83.8 bits, see alignment E=6.4e-28

Best Hits

KEGG orthology group: K07300, Ca2+:H+ antiporter (inferred from 100% identity to syf:Synpcc7942_0023)

Predicted SEED Role

"H+/Ca2+ exchanger"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31SB4 at UniProt or InterPro

Protein Sequence (354 amino acids)

>Synpcc7942_0023 calcium/proton exchanger (Synechococcus elongatus PCC 7942)
MSIKSLISFGLLVFVPISIAAEWLHWGEGAIFVTSALAIVPLAIWLSTATEEIAVVVGPS
IGALLNAVFGNATELIIAVVALRAGLVDIVKASITGTIISNLLLAMGLSMLVGGIGRQEQ
TFKPVVARVNGSAMTLAVLAILLPTLAIATGGETPPSELGFSQFVAWILLAVYGLTLLFS
LKTHRSLYDVGVTEHEHSGDRPNLLLWVGVLAAATLAVAYESEIFVGVVESVTEKVGLSP
LFTGVILLPLLGGAAEYVTAVSVARKDNMDLSVSVALGSTLLVALFVAPLLVLIGPLFGH
PLDLSFNLFELVAVVVAVAVSNLISIDGRSDWLEGCLLLAAYLILGAAFYFQSA