Protein Info for SMc04247 in Sinorhizobium meliloti 1021

Annotation: beta-xylosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 541 PF04616: Glyco_hydro_43" amino acids 5 to 303 (299 residues), 350.3 bits, see alignment E=8.5e-109 PF17851: GH43_C2" amino acids 333 to 537 (205 residues), 183.7 bits, see alignment E=3.7e-58

Best Hits

Swiss-Prot: 52% identical to XYNB_BACSU: Beta-xylosidase (xynB) from Bacillus subtilis (strain 168)

KEGG orthology group: K01198, xylan 1,4-beta-xylosidase [EC: 3.2.1.37] (inferred from 100% identity to sme:SMc04247)

Predicted SEED Role

"Beta-xylosidase (EC 3.2.1.37)" in subsystem Xylose utilization (EC 3.2.1.37)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.37

Use Curated BLAST to search for 3.2.1.37

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92P74 at UniProt or InterPro

Protein Sequence (541 amino acids)

>SMc04247 beta-xylosidase (Sinorhizobium meliloti 1021)
MTATIRNPILPGFNPDPSICRVGEDYYIATSTFEWYPGVQIHHSRDLVNWRLVRRPLERA
SQLDMRGNPDSCGVWAPCLSYCDGLFWLVYTDVKRLDGNFKDAHNYIVTAEAVEATWSDP
VYVNSSGFDPSLFHDDDGRKWFLNMQWNHRSESFAGSPKSPAFDGILLQEWDERTRKLVG
PVKNIFAGSPLGLVEGPHLFKRDGWYYLTVAEGGTGYDHAVGMARSRTIDGPYEMHPNVH
LITSKDHPEAALQRAGHGQYVETPDGQAYHTHLCGRPLPPQRRCTLGRETALQKCVWRED
GWLYLENGGPVPGVTVPAPGAAGTVAERVLFETDFDEQVLPPEFQWLRTPVPERIFSLAA
RTGHLRLFGRESIGSWFEQALVARRQEHHSFRAEAVVDFAPDTYQQVAGLTHYYNRHKFH
ALGVTRHETLGRVLTILSCPGDFPNGRLTYPVGSGFAVPDGPVQLAMEVRDNDLQFFWRG
AAQAEWLTIGPVLDAGVISDEGGRGEHGSFTGAFAGIFAFDISGCATPADFDRFRYQALS
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