Protein Info for SMc02940 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02432: tRNA(Ile)-lysidine synthetase
  • amino acids 21 to 215 (195 residues), 152 bits, E=9e-49
• PF01171: ATP_bind_3
  • amino acids 22 to 213 (192 residues), 144.9 bits, E=1.1e-46

Best Hits

Swiss-Prot: 100% identical to TILS_RHIME: tRNA(Ile)-lysidine synthase (tilS) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K04075, tRNA(Ile)-lysidine synthase [EC: 6.3.4.-] (inferred from 100% identity to smk:Sinme_2791)

Predicted SEED Role

"tRNA(Ile)-lysidine synthetase (EC 6.3.4.19)" (EC 6.3.4.19)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.4.- or 6.3.4.19

Sequence Analysis Tools

See Q92JY3 at UniProt or InterPro

Protein Sequence (453 amino acids)

>SMc02940 hypothetical protein (Sinorhizobium meliloti 1021)
MPHAVLDTARNFLRSFITPRRILVAVSGGSDSMGLLVALHSAIAADERRGFSLAACTVDH
ALRPQSACEAEDVAAFCAALGIAHRICRWEGAKPSTGIQAAARNKRYELLAEAADALGAD
CIAIGHTRDDQQETVAMRIARGKGDGAGDGQGEGHGGAGMAASMLYGRRIWVLRPFLGLA
RAEIRSFLQARGVSWIDDPSNANPAFERVRVRARIATSGGMPTPLGNGRQRAASSARAAA
LIEKRIRVHEALVAEVSARHAGEIDDPDWRRALLTVASVLGGREHMPAFATVQRLSQFLR
SGEPGRMTAGRVVFDRRASGLYLYREARNLPVLAVGPGRQGAWDGRFTVKSRGPAVTVAA
DASGRLWTKRLIDAGLPAGIAKRGSTVAPEIASTDGAGLAFGEAPAQVEYHIGLYDTFLP
GFDRIMADAVAVSFGRDRYPAPPVHDVLIEMET