Protein Info for SMc02428 in Sinorhizobium meliloti 1021

Annotation: oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 506 PF01946: Thi4" amino acids 30 to 67 (38 residues), 27.2 bits, see alignment 7.7e-10 PF00890: FAD_binding_2" amino acids 31 to 211 (181 residues), 29.3 bits, see alignment E=1.8e-10 PF01266: DAO" amino acids 31 to 376 (346 residues), 175.9 bits, see alignment E=6.1e-55 PF12831: FAD_oxidored" amino acids 31 to 85 (55 residues), 27.3 bits, see alignment 8.1e-10 PF13450: NAD_binding_8" amino acids 34 to 69 (36 residues), 31.4 bits, see alignment 6.6e-11 PF00355: Rieske" amino acids 432 to 503 (72 residues), 35.8 bits, see alignment E=2.1e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMc02428)

Predicted SEED Role

"oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92ML0 at UniProt or InterPro

Protein Sequence (506 amino acids)

>SMc02428 oxidoreductase (Sinorhizobium meliloti 1021)
MTAHDERTVSLWAAIKVAPDAAPLRQDDHVDVVVVGSGIAGLSVAYELALAGLKVAVIDR
GRIGGGMTARTTAHLTSICDDYFSKLIDLRGREMARLFHESQSAAIDRIEAIQETEAVAC
DFRRVDGFLFPSTGDQEATLDRELDAARQIGVDAERITGVPFAGFSATPALRYSRQATFH
PLKYLRGLAAGIRARGGMLYSETVVEEVEETKDGVRVATDAGFEVAAMWAVVATNSPIND
RVALHTKQAPYRTYAMSFEIGRGLIPDGLYWDTEDPYHYVRLQRGDNETDFLVVGGEDHK
TGAADDGEERFSALADWTKRLVPNLGVVTHRWSGQVMETIDYAGFIGRNPGNERVFVVTG
DSGEGMTHGVAASLLIRALVLDGDSGWRGLYEPSRKTLRAIGDYLSENSTAIKNFSEYVA
PGEIESIDALRPGEGAIVREGLTKVAAFRDDDGTLYRRSASCTHVGCHVHWNSLERCWDC
PCHGSHFAVDGTVLNGPAVSPLADPG