Protein Info for SMc02345 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 287 transmembrane" amino acids 29 to 51 (23 residues), see Phobius details amino acids 57 to 80 (24 residues), see Phobius details amino acids 95 to 116 (22 residues), see Phobius details amino acids 131 to 149 (19 residues), see Phobius details amino acids 155 to 174 (20 residues), see Phobius details amino acids 194 to 212 (19 residues), see Phobius details amino acids 219 to 238 (20 residues), see Phobius details amino acids 250 to 269 (20 residues), see Phobius details PF00528: BPD_transp_1" amino acids 106 to 274 (169 residues), 87.3 bits, see alignment E=5.4e-29

Best Hits

Swiss-Prot: 34% identical to SSUC_ECOLI: Putative aliphatic sulfonates transport permease protein SsuC (ssuC) from Escherichia coli (strain K12)

KEGG orthology group: K02050, sulfonate/nitrate/taurine transport system permease protein (inferred from 100% identity to smk:Sinme_2624)

MetaCyc: 34% identical to aliphatic sulfonate ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-56-RXN [EC: 7.6.2.14]

Predicted SEED Role

"ABC-type nitrate/sulfonate/bicarbonate transport system, permease component" in subsystem Alkanesulfonate assimilation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92MP0 at UniProt or InterPro

Protein Sequence (287 amino acids)

>SMc02345 ABC transporter permease (Sinorhizobium meliloti 1021)
MSLIADRNPPLRSSLVLRRKRALPKTPTALGRTFTTITLGLPAVIAFALLWEIAPRAGWI
NALFFPPLSQVLAVLWEMIVSGQLADHIGISLERAAIGFLLACVTAVPLGFLMGRYSLFE
KASDFLVQTLRNTSQFALLPVFIIVLGIGEASKIAITFYAAVFFLLINTIVGVKSVDPLL
VKAARSMGTSDWDLFKKVIFPSAIPSIVAGARLGVKTSLFSVIAAEMLAAQSGIGYLIQH
SSLMLETDRMYAGILTLTIIGLLLNYLLVAGERRATRWRGSAESGPN