Protein Info for SMc02065 in Sinorhizobium meliloti 1021

Annotation: SEC-independent translocase transmembrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 transmembrane" amino acids 22 to 41 (20 residues), see Phobius details amino acids 83 to 104 (22 residues), see Phobius details amino acids 116 to 139 (24 residues), see Phobius details amino acids 171 to 197 (27 residues), see Phobius details amino acids 210 to 225 (16 residues), see Phobius details amino acids 231 to 250 (20 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 12 to 241 (230 residues), 205.9 bits, see alignment E=3.7e-65 PF00902: TatC" amino acids 14 to 236 (223 residues), 235.3 bits, see alignment E=3.2e-74

Best Hits

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 100% identity to sme:SMc02065)

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Q23 at UniProt or InterPro

Protein Sequence (280 amino acids)

>SMc02065 SEC-independent translocase transmembrane protein (Sinorhizobium meliloti 1021)
MSRDIEDRPQPLIEHLIELRTRLMWAVGAFFVAFLVCFYFAKQLFNLLVLPFKWAVSWAG
LSHRNVELIYTAPQEFFFTQIKVAMFGALVIAFPVIASQVYRFVAPGLYKNERAAFLPFL
VASPLLFLLGGALVYFFFTPMVMWFFLAMEQGGGEGQVAIQLLPKVSEYLSLIMSLVFAF
GLVFQLPVITTLLARVGFVTSQGLAEKRKYAIVIAFVVAAVLTPPDPVSQIGLALPAILL
YEISIYTARIVERRRAAEALEREAASEQESSSETADPAKG